Brief Information of the Compound and Protein
Compound Name
2-[4-[4-[(7-pyrazin-2-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)amino]phenyl]piperidin-1-yl]acetamide
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PubChem ID
CID: 46852510
SID: 99241571
Canonical SMILES
NC(=O)CN1CCC(CC1)c1ccc(Nc2ncc3ccc(-c4cnccn4)n3n2)cc1
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Compound Formula C23H24N8O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 282 nM
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