Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BDBM50249542
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 PubChem ID
CID: 11213558
SID: 16296087
Canonical SMILES
COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)cc(OC)c1OC
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Compound Formula C22H23FN6O5
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM
2 Kd = 3.5 nM