4-[3-[2-[3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propyl]cyclopropyl]propoxy]-N-cyclopropyl-2-fluorobenzamide

ethyl (3R)-3-benzyl-10-[4-(trifluoromethyl)phenyl]-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

5-[4-[(1R,2R)-2-[(4-ethylsulfonyl-2-fluorophenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole

tert-butyl 4-[1-(2-cyano-6-methylpyrimidin-4-yl)piperidin-4-yl]piperidine-1-carboxylate

N-(2-methoxyethyl)-N,2-dimethyl-3-phenyl-2-[3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]propanamide

ethyl (2R)-2-methyl-2-[6-methyl-3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]-3-phenylpropanoate

2-[4-[(1R,2R)-2-[[3-fluoro-4-(tetrazol-1-yl)phenyl]methoxymethyl]cyclopropyl]piperidin-1-yl]-5-(methoxymethyl)pyrimidine

5-ethyl-2-[4-[(1R,2R)-2-[(5-methylsulfonylpyridin-2-yl)methoxymethyl]cyclopropyl]piperidin-1-yl]pyrimidine

5-ethoxy-2-[4-[(1R,2R)-2-[(3-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]pyrimidine

5-[4-[(1R,2S)-2-[2-(4-ethylsulfonyl-2-fluorophenoxy)ethyl]cyclopropyl]piperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole

5-[4-[(1R,2R)-2-[[2-fluoro-4-(tetrazol-1-yl)phenyl]methoxymethyl]cyclopropyl]piperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole

4-(1'-(5-chloropyrimidin-2-yl)-4,4'-bipiperidin-1-yl)-6-methylpyrimidine-2-carbonitrile

6-methyl-2-(2-((1S,2R)-2-(1-(5-methylpyrimidin-2-yl)piperidin-4-yl)cyclopropyl)ethoxy)pyrimidine-4-carbonitrile

tert-butyl 4-[1-(6-cyano-2-methylpyrimidin-4-yl)piperidin-4-yl]piperidine-1-carboxylate

2-(4-((1R,2S)-2-(2-(5-(1H-1,2,3-triazol-1-yl)pyridin-2-yloxy)ethyl)cyclopropyl)piperidin-1-yl)-5-chloropyrimidine

methyl 3-benzyl-10-[4-(trifluoromethyl)phenyl]-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

[(3R)-3-cyclopropyl-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraen-11-yl]methanol

(3S)-3-[(3-fluorophenyl)methyl]-N-(2-methoxyethyl)-N-methyl-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxamide

[2H]-(S)-methyl 8-(3-fluorobenzyl)-2-(hydroxymethyl)-3-(4-(trifluoromethyl)phenyl)-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[3,4-e]pyrimidine-8-carboxylate

2-[4-[(1R,2R)-2-[(2-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-5-(methoxymethyl)pyrimidine

2-[4-[[(1R,2R)-2-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]cyclopropyl]methoxymethyl]-3-fluorophenyl]sulfonylethanol

5-fluoro-2-[4-[(1R,2R)-2-[(3-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]pyrimidine

5-ethyl-2-[4-[(1R,2R)-2-[(3-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]pyrimidine

tert-butyl 4-[[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]-(trifluoromethyl)amino]piperidine-1-carboxylate

6-(1-methylsulfonylpiperidin-4-yl)oxy-N-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]-N-(trifluoromethyl)pyrimidin-4-amine

6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)-N-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]-N-(trifluoromethyl)pyrimidin-4-amine

ethyl (2R)-2-[6-chloro-3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

ethyl (3R)-3-benzyl-10-(4-chlorophenyl)-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

methyl (3S)-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

methyl (3R)-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

2-[3-fluoro-4-[[(1R,2R)-2-[1-[5-(methoxymethyl)pyrimidin-2-yl]piperidin-4-yl]cyclopropyl]methoxymethyl]phenyl]-1-morpholin-4-ylethanone

S-propan-2-yl 4-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]oxypiperidine-1-carbothioate

2-[4-[(1R,2R)-2-[(3-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-5-(methoxymethyl)pyrimidine

tert-butyl 4-[[6-(1-methylsulfonylpiperidin-4-yl)oxypyrimidin-4-yl]-(trifluoromethyl)amino]piperidine-1-carboxylate

2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]propyl 7-fluoro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

5-chloro-2-(4-((1R,2S)-2-(2-(5-(methylsulfonyl)pyridin-2-yloxy)ethyl)cyclopropyl)piperidin-1-yl)pyrimidine

2-(4-((1R,2S)-2-(2-(4-(1H-1,2,3-triazol-1-yl)phenoxy)ethyl)cyclopropyl)piperidin-1-yl)-5-chloropyrimidine

2-methoxyethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

5-[4-[(1R,2R)-2-[(2-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole

2-[4-[(1R,2R)-2-[(2-fluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-5-methoxypyrimidine

2-[4-[(1R,2R)-2-[(3,5-difluoro-4-methylsulfonylphenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-5-(methoxymethyl)pyrimidine

N-[1-[3-(2-fluoropropan-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-4-yl]-6-(1-methylsulfonylpiperidin-4-yl)oxy-N-(trifluoromethyl)pyrimidin-4-amine

(1-methylcyclopropyl) 4-[(1R,2R)-2-[[2-fluoro-4-(tetrazol-1-yl)phenyl]methoxymethyl]cyclopropyl]piperidine-1-carboxylate

1-(5-chloropyrimidin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine

methyl (3S)-3-[(3-fluorophenyl)methyl]-11-(hydroxymethyl)-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

N-[1-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]-6-(1-methylsulfonylpiperidin-4-yl)oxy-N-(trifluoromethyl)pyrimidin-4-amine

tert-butyl 4-[1-(6-cyanopyrimidin-4-yl)piperidin-4-yl]piperidine-1-carboxylate

tert-butyl 4-[1-(2-cyanopyrimidin-4-yl)piperidin-4-yl]piperidine-1-carboxylate

[(3R)-3-cyclopropyl-3-[(3-fluorophenyl)methyl]-10-[6-(trifluoromethyl)pyridin-3-yl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraen-11-yl]methanol

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]propyl 7-fluoro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

methyl 3-benzyl-10-(4-cyanophenyl)-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

2-[4-[(1R,2R)-2-[(4-ethylsulfonyl-2-fluorophenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-5-(methoxymethyl)pyrimidine

5-[4-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]oxypiperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole

2-methyl-6-(1'-(5-methylpyrimidin-2-yl)-4,4'-bipiperidin-1-yl)pyrimidine-4-carbonitrile

ethyl (9R)-9-benzyl-3-[4-(trifluoromethyl)phenyl]-7,8-dihydro-6H-pyrazolo[1,5-a]quinazoline-9-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]propyl 5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

5-chloro-2-[4-[(1R,2R)-2-[(5-methylsulfonylpyridin-2-yl)methoxymethyl]cyclopropyl]piperidin-1-yl]pyrimidine

2-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]-1,2-thiazolidine 1,1-dioxide

ethyl (2R)-2-methyl-3-phenyl-2-[3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]propanoate

tert-butyl 4-[1-(4-methylsulfinylphenyl)piperidin-4-yl]piperidine-1-carboxylate

1-[6-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]oxypyrimidin-4-yl]-5-methylsulfonyl-2,3-dihydroindole

ethyl 2-methyl-3-phenyl-2-[3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]propanoate

methyl 3-benzyl-10-[4-(trifluoromethyl)phenyl]-5-oxa-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

1-(4-(methylsulfonyl)phenyl)-1'-(5-(trifluoromethyl)pyridin-2-yl)-4,4'-bipiperidine

tert-butyl 4-[ethyl-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate

methyl (3S)-3-[(3-fluorophenyl)methyl]-11-(hydroxymethyl)-10-[6-(trifluoromethyl)pyridin-3-yl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

4-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]morpholin-3-one

tert-butyl 4-[4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]piperidine-1-carboxylate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-3-phenylpropanoate

(3S)-3-hydroxy-1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperidin-2-one

propan-2-yl 4-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]oxypiperidine-1-carboxylate

ethyl (2R)-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperidin-2-one

3-hydroxy-1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperidin-2-one

1-(5-methylpyridin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine

tert-butyl 4-[[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]-propylamino]piperidine-1-carboxylate

4-methyl-6-(1'-(5-methylpyrazin-2-yl)-4,4'-bipiperidin-1-yl)pyrimidine-2-carbonitrile

1-(5-fluoropyridin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine

ethyl (2R)-2-methyl-3-phenyl-2-[8-[4-(trifluoromethyl)phenyl]pyrazolo[5,1-c][1,2,4]triazin-4-yl]propanoate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

methyl (3S)-11-carbamoyl-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

ethyl 3-benzyl-10-(4-phenoxyphenyl)-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 7-chloro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

3-cyclopropyl-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene

tert-butyl 4-[methyl-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate

tert-butyl 4-[1-(4-methylsulfonylphenyl)piperidin-4-yl]piperidine-1-carboxylate

ethyl (2R)-2-methyl-2-[2-methyl-3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]-3-phenylpropanoate

2-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]-1,2,6-thiadiazinane 1,1-dioxide

tert-butyl 4-[1-(4-acetylphenyl)piperidin-4-yl]piperidine-1-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 4-fluoro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 7-fluoro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

ethyl (3S)-3-benzyl-10-[4-(trifluoromethyl)phenyl]-1,5,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

(3R)-3-hydroxy-1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperidin-2-one

tert-butyl 4-[2-methoxyethyl-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate

2-methyl-6-(1'-(5-methylpyrazin-2-yl)-4,4'-bipiperidin-1-yl)pyrimidine-4-carbonitrile

1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]pyrrolidin-2-one

methyl 3-benzyl-10-[4-(trifluoromethyl)phenyl]-4-oxa-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

[2H]-(S)-methyl 8-(3-fluorobenzyl)-2-(hydroxymethyl)-3-(6-(trifluoromethyl)pyridin-3-yl)-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[3,4-e]pyrimidine-8-carboxylate

1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperazin-2-one;hydrochloride

ethyl (3S)-3-benzyl-10-[4-(trifluoromethyl)phenyl]-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

1-(4-(methylsulfonyl)phenyl)-1'-(pyridin-2-yl)-4,4'-bipiperidine

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-(3-methylphenyl)propanoate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-(1,3-thiazol-4-yl)propanoate

2-[[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]sulfonyl]ethanol

tert-butyl 4-[[6-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-4-yl]-(trifluoromethyl)amino]piperidine-1-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 7-methyl-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

1-(5-chloropyridin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine

2-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]cyclohexan-1-one

2-[[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]sulfinyl]ethanol

tert-butyl 4-[cyclopropylmethyl-[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate

ethyl 2-[7-(4-chlorophenyl)pyrazolo[5,1-b][1,3]thiazol-3-yl]-2-methyl-3-phenylpropanoate

1-(5-methylpyrimidin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine

ethyl 2-[3-(6-chloropyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

6-(1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidin-1-yl)nicotinonitrile

ethyl 2-[8-(4-chlorophenyl)imidazo[1,5-a]pyrimidin-4-yl]-2-methyl-3-phenylpropanoate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-(oxan-4-yl)propanoate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-pyridin-3-ylpropanoate

methyl (3S)-3-[(3-fluorophenyl)methyl]-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-3-carboxylate

methyl 14-benzyl-5-[4-(trifluoromethyl)phenyl]-2,3,7-triazatricyclo[7.5.0.02,6]tetradeca-1(9),3,5,7-tetraene-14-carboxylate

N-methyl-N-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]acetamide

tert-butyl 4-[1-(4-carbamoylphenyl)piperidin-4-yl]piperidine-1-carboxylate

N-[1-phenyl-2-[3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]propan-2-yl]acetamide

propan-2-yl 4-[2-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyridin-4-yl]oxypiperidine-1-carboxylate

4-hydroxy-1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperidin-2-one

5-hydroxy-1-[1-[6-[1-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-4-yl]oxypyrimidin-4-yl]-2,3-dihydroindol-5-yl]piperidin-2-one

1-(4-(methylsulfonyl)phenyl)-1'-(pyrimidin-2-yl)-4,4'-bipiperidine

ethyl 15-benzyl-5-[4-(trifluoromethyl)phenyl]-2,3,7-triazatricyclo[7.6.0.02,6]pentadeca-1(9),3,5,7-tetraene-15-carboxylate

tert-butyl 4-(1-pyrazin-2-ylpiperidin-4-yl)piperidine-1-carboxylate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-(2-methylphenyl)propanoate

tert-butyl 4-(1-pyrimidin-4-ylpiperidin-4-yl)piperidine-1-carboxylate

tert-butyl 4-[4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)-4-oxobutyl]piperidine-1-carboxylate

methyl 3-benzyl-10-(4-methylsulfonylphenyl)-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

ethyl 2-[3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-(4-methylphenyl)propanoate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 6-fluoro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

5-methyl-2-[1-phenyl-2-[3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]propan-2-yl]-1,3-oxazole

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2,4-dimethylpentanoate

ethyl 2-[3-(2-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-phenylpropanoate

ethyl 2-benzyl-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]pentanoate

ethyl 3-phenyl-2-(3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)propanoate

ethyl 3-(2-chloro-6-fluorophenyl)-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]propanoate

1-(4-(methylsulfonyl)phenyl)-1'-(pyrazin-2-yl)-4,4'-bipiperidine

ethyl 3-benzyl-4-methyl-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

7-(2-methylsulfonyl-1-phenylpropan-2-yl)-3-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine

tert-butyl 4-[[6-(4-methylsulfonylcyclohexyl)oxypyrimidin-4-yl]-(trifluoromethyl)amino]piperidine-1-carboxylate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-phenylacetate

ethyl 3-[(3-fluorophenyl)methyl]-5-oxo-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

tert-butyl 4-[[6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate

tert-butyl 4-[1-(4-methylphenyl)piperidin-4-yl]piperidine-1-carboxylate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-2-methyl-3-(1-methylsulfonylpiperidin-4-yl)propanoate

3-[(3-fluorophenyl)methyl]-3-methyl-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene

propan-2-yl 4-[3-(5-methylsulfonyl-2,3-dihydroindol-1-yl)phenoxy]piperidine-1-carboxylate

tert-butyl 4-[1-(3-methylphenyl)piperidin-4-yl]piperidine-1-carboxylate

propan-2-yl 4-[[4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)-1,3,5-triazin-2-yl]oxy]piperidine-1-carboxylate

tert-butyl 4-(1-pyrimidin-2-ylpiperidin-4-yl)piperidine-1-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 4-chloro-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

methyl (3S)-3-[(3-fluorophenyl)methyl]-11-(2-hydroxypropan-2-yl)-10-[4-(trifluoromethyl)phenyl]-1,4,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate

tert-butyl 4-[7-(1-ethoxy-2-methyl-1-oxo-3-phenylpropan-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]piperidine-1-carboxylate

tert-butyl 4-[1-(4-methylsulfanylphenyl)piperidin-4-yl]piperidine-1-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 4-methyl-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

tert-butyl 4-(1-pyridin-2-ylpiperidin-4-yl)piperidine-1-carboxylate

ethyl 2-methyl-3-phenyl-2-[3-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-yl]propanoate

tert-butyl 4-[[6-[(1-methylsulfonylazetidin-3-yl)methoxy]pyrimidin-4-yl]-(trifluoromethyl)amino]piperidine-1-carboxylate

ethyl 3-phenyl-2-[9-[4-(trifluoromethoxy)phenyl]-4,5-dihydropurin-6-yl]propanoate

ethyl 2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]propanoate

ethyl 3-(2-chloro-6-fluorophenyl)-2-[3-(4-methylsulfonylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]propanoate

tert-butyl 4-(1-phenylpiperidin-4-yl)piperidine-1-carboxylate

tert-butyl 4-[4-(5-methylsulfonyl-2,3-dihydroindol-1-yl)butyl]piperidine-1-carboxylate

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 7-methoxy-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate

tert-butyl 4-[1-(3-methylsulfonylphenyl)piperidin-4-yl]piperidine-1-carboxylate

[2-hydroxy-2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl] 5-methylsulfonyl-2,3-dihydroindole-1-carboxylate