General Information of the Compound
Compound ID
CP0572043
Compound Name
CHEMBL4846489
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Formula
C22H33F3N4O5S
Molecular Weight
522.59
Canonical SMILES
CC(C)(C)OC(=O)N1CCC(CC1)N(c1cc(O[C@H]2CC[C@@H](CC2)S(C)(=O)=O)ncn1)C(F)(F)F
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InChI
InChI=1S/C22H33F3N4O5S/c1-21(2,3)34-20(30)28-11-9-15(10-12-28)29(22(23,24)25)18-13-19(27-14-26-18)33-16-5-7-17(8-6-16)35(4,31)32/h13-17H,5-12H2,1-4H3/t16-,17-
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InChIKey
BXEUHEQRTPFPIO-QAQDUYKDSA-N
Physicochemical Property
logP
3.9369
Rotatable Bonds
5
Heavy Atom Count
35
Polar Areas
101.93
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4846489
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 270 nM
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