General Information of the Compound
Compound ID
CP0432263
Compound Name
2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]ethyl 6-methoxy-5-methylsulfonyl-2,3-dihydroindole-1-carboxylate
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Structure
Formula
C23H34N2O7S
Molecular Weight
482.599
Canonical SMILES
COc1cc2N(CCc2cc1S(C)(=O)=O)C(=O)OCCC1CCN(CC1)C(=O)OC(C)(C)C
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InChI
InChI=1S/C23H34N2O7S/c1-23(2,3)32-21(26)24-10-6-16(7-11-24)9-13-31-22(27)25-12-8-17-14-20(33(5,28)29)19(30-4)15-18(17)25/h14-16H,6-13H2,1-5H3
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InChIKey
ZTJCTJJPHSUKRV-UHFFFAOYSA-N
Physicochemical Property
logP
3.635
Rotatable Bonds
5
Heavy Atom Count
33
Polar Areas
102.45
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76317666
ChEMBL ID
CHEMBL3113635
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 4800 nM
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