General Information of the Compound
Compound ID
CP0447280
Compound Name
ethyl 3-benzyl-10-(4-phenoxyphenyl)-1,8,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),7,9,11-tetraene-3-carboxylate
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Structure
Formula
C31H27N3O3
Molecular Weight
489.575
Canonical SMILES
CCOC(=O)C1(Cc2ccccc2)CCc2cnc3c(cnn3c12)-c1ccc(Oc2ccccc2)cc1
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InChI
InChI=1S/C31H27N3O3/c1-2-36-30(35)31(19-22-9-5-3-6-10-22)18-17-24-20-32-29-27(21-33-34(29)28(24)31)23-13-15-26(16-14-23)37-25-11-7-4-8-12-25/h3-16,20-21H,2,17-19H2,1H3
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InChIKey
JXQXSHWFIWWHOS-UHFFFAOYSA-N
Physicochemical Property
logP
6.1784
Rotatable Bonds
7
Heavy Atom Count
37
Polar Areas
65.72
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118720415
ChEMBL ID
CHEMBL3354787
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 20 nM
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