| Compound ID |
Compound Name |
Compound Formula |
|
CP0508585
|
7-(2-chloro-4-methoxyphenyl)-N,N-bis(cyclopropylmethyl)-2-ethylpyrazolo[1,5-a]pyridin-3-amine
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|
C24H28ClN3O
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0424518
|
N,N-bis(cyclopropylmethyl)-2-ethyl-7-(2-methoxy-4-methylphenyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C25H31N3O
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0424519
|
N,N-bis(cyclopropylmethyl)-2-ethyl-7-(4-methoxy-2,6-dimethylphenyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C26H33N3O
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 90 nM
|
|
|
|
CP0424477
|
7-(2-chloro-4-methoxyphenyl)-2-ethyl-N,N-dipropylpyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C22H28ClN3O
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0424517
|
N,N-bis(cyclopropylmethyl)-2-ethyl-7-(4-methoxy-2-methylphenyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C25H31N3O
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0283841
|
Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine
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|
C24H34N4
|
1
|
| 1 |
IC50 = 18.62 nM
|
|
|
|
CP0535889
|
N-(cyclopropylmethyl)-7-(2,6-dimethoxy-4-methylphenyl)-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O3
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0527012
|
N-(cyclopropylmethyl)-2-ethyl-N-(3-fluoropropyl)-7-(2-methoxy-4,6-dimethylphenyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C25H32FN3O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0424479
|
N-(cyclopropylmethyl)-2-ethyl-7-(2-methoxy-4,6-dimethylphenyl)-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0408559
|
2-[2-chloro-6-methoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine
Show/Hide
|
C24H29ClN2O3
|
2
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
IC50 = 67 nM
|
|
|
|
CP0428957
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-ethyl-N-(2-methoxyethyl)-3,8-dimethylquinolin-5-amine
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|
C26H34N2O4
|
2
|
| 1 |
IC50 = 23 nM
|
|
|
| 2 |
IC50 = 109 nM
|
|
|
|
CP0521864
|
N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C29H39N3O4
|
2
|
| 1 |
IC50 = 23 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0481401
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3,8-dimethylquinolin-5-amine
Show/Hide
|
C25H32N2O3
|
2
|
| 1 |
IC50 = 24 nM
|
|
|
| 2 |
IC50 = 79 nM
|
|
|
|
CP0424476
|
N,N-bis(cyclopropylmethyl)-2-ethyl-7-(2-methoxy-4,6-dimethylphenyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C26H33N3O
|
2
|
| 1 |
IC50 = 24 nM
|
|
|
| 2 |
IC50 = 59 nM
|
|
|
|
CP0462426
|
N-(cyclopropylmethyl)-7-(2,6-dimethoxy-4-methylphenyl)-2-methoxy-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H35N3O4
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
|
CP0375845
|
N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-(1,4-dioxan-2-ylmethyl)-2-methylsulfanylpyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H35N3O5S
|
2
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
|
CP0514100
|
8-chloro-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3-methylquinolin-5-amine
Show/Hide
|
C24H29ClN2O3
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
IC50 = 62 nM
|
|
|
|
CP0512441
|
N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-methylsulfanyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O4S
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0449917
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N,3-triethyl-8-methoxyquinolin-5-amine
Show/Hide
|
C26H34N2O4
|
2
|
| 1 |
IC50 = 32 nM
|
|
|
| 2 |
IC50 = 108 nM
|
|
|
|
CP0512444
|
7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-(2-methoxyethyl)-2-methylsulfanyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H37N3O5S
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 124 nM
|
|
|
|
CP0525269
|
N-(cyclopropylmethyl)-2-ethyl-7-(2-methoxy-4,6-dimethylphenyl)-N-(oxolan-2-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H35N3O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0446318
|
5-(diethylamino)-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3-methylquinoline-8-carbonitrile
Show/Hide
|
C25H29N3O3
|
2
|
| 1 |
IC50 = 36 nM
|
|
|
| 2 |
IC50 = 102 nM
|
|
|
|
CP0424478
|
N-(cyclopropylmethyl)-2-ethyl-7-(2-methoxy-4,6-dimethylphenyl)-N-(oxolan-3-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H35N3O2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0512443
|
N-(cyclopropylmethyl)-7-(2,6-dimethoxy-4-methylphenyl)-2-methylsulfanyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H35N3O3S
|
2
|
| 1 |
IC50 = 39 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0424520
|
7-(2,6-dimethoxy-4-methylphenyl)-2-ethyl-N-(oxan-4-ylmethyl)-N-propylpyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0526971
|
N-(cyclopropylmethyl)-7-(2,4-dimethoxy-6-methylphenyl)-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0398027
|
N-(cyclopropylmethyl)-2-ethyl-7-(2-methoxy-4,6-dimethylphenyl)-N-(2-methoxyethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0462424
|
N-(cyclopropylmethyl)-2-ethyl-N-(oxan-4-ylmethyl)-7-(2,4,6-trimethoxyphenyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O4
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0376551
|
2-(2,6-dimethoxy-4-methylphenyl)-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine
Show/Hide
|
C24H30N2O3
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 99 nM
|
|
|
|
CP0388821
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxolan-2-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C25H33N3O5S
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0412577
|
3-chloro-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methylquinolin-5-amine
Show/Hide
|
C24H29ClN2O3
|
2
|
| 1 |
IC50 = 45 nM
|
|
|
| 2 |
IC50 = 81 nM
|
|
|
|
CP0383194
|
N,N-bis(cyclopropylmethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3,8-dimethylquinolin-5-amine
Show/Hide
|
C29H36N2O3
|
2
|
| 1 |
IC50 = 46 nM
|
|
|
| 2 |
IC50 = 88 nM
|
|
|
|
CP0324234
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methyl-N-(oxan-4-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C26H35N3O4S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0500921
|
4-[7-[butyl(oxan-4-yl)amino]-6-methoxypyrazolo[5,1-b][1,3]thiazol-3-yl]-3,5-dimethoxybenzonitrile
Show/Hide
|
C24H30N4O4S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0227068
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(2-methoxyethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C23H31N3O5S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0520732
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxolan-3-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C25H33N3O5S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0530389
|
N-(cyclopropylmethyl)-7-[4-(ethoxymethyl)-2,6-dimethoxyphenyl]-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C30H41N3O4
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0526974
|
N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-methyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O4
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0511245
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-3-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C26H35N3O5S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0425422
|
N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-methoxy-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H37N3O5
|
2
|
| 1 |
IC50 = 51 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0512442
|
3-[cyclopropylmethyl(oxan-4-ylmethyl)amino]-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]pyrazolo[1,5-a]pyridine-2-carbonitrile
Show/Hide
|
C28H34N4O4
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0465391
|
N-butyl-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-yl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C25H35N3O5S
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0512454
|
2-ethyl-7-(4-methoxy-2-methylphenyl)-N,N-dipropylpyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C23H31N3O
|
2
|
| 1 |
IC50 = 57 nM
|
|
|
| 2 |
IC50 = 480 nM
|
|
|
|
CP0514099
|
3-chloro-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxyquinolin-5-amine
Show/Hide
|
C24H29ClN2O4
|
2
|
| 1 |
IC50 = 57 nM
|
|
|
| 2 |
IC50 = 144 nM
|
|
|
|
CP0328875
|
US850504, 91
Show/Hide
|
C26H34FN3O5S
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0553480
|
4-[5-(diethylamino)-8-methoxy-3-methylquinolin-2-yl]-3,5-dimethoxybenzonitrile
Show/Hide
|
C24H27N3O3
|
2
|
| 1 |
IC50 = 63 nM
|
|
|
| 2 |
IC50 = 132 nM
|
|
|
|
CP0520729
|
3-[2-chloro-6-methoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-yl)-N-propylpyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C23H30ClN3O4S
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0523467
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-8-methoxy-N-(2-methoxyethyl)-3-methyl-N-(2-methylpropyl)quinolin-5-amine
Show/Hide
|
C28H38N2O5
|
2
|
| 1 |
IC50 = 65 nM
|
|
|
| 2 |
IC50 = 156 nM
|
|
|
|
CP0391275
|
3-[4-(ethoxymethyl)-2,6-dimethoxyphenyl]-6-methoxy-N-(oxan-4-yl)-N-propylpyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C25H35N3O5S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0377471
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-fluoro-3-methylquinolin-5-amine
Show/Hide
|
C24H29FN2O3
|
2
|
| 1 |
IC50 = 67 nM
|
|
|
| 2 |
IC50 = 226 nM
|
|
|
|
CP0391276
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C26H35N3O5S
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0438378
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-N,N-diethyl-3-methylquinolin-5-amine
Show/Hide
|
C24H30N2O4
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
IC50 = 167 nM
|
|
|
|
CP0497737
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3,8-dimethyl-N,N-dipropylquinolin-5-amine
Show/Hide
|
C27H36N2O3
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
IC50 = 88 nM
|
|
|
|
CP0388820
|
N-butyl-3-[4-(ethoxymethyl)-2,6-dimethoxyphenyl]-6-methoxy-N-(oxan-4-yl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C26H37N3O5S
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0437817
|
5-N,5-N-bis(cyclopropylmethyl)-3-methyl-2-N-(2,4,6-trimethylphenyl)quinoline-2,5-diamine
Show/Hide
|
C27H33N3
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0507253
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3-fluoro-8-methoxyquinolin-5-amine
Show/Hide
|
C24H29FN2O4
|
2
|
| 1 |
IC50 = 75 nM
|
|
|
| 2 |
IC50 = 118 nM
|
|
|
|
CP0465392
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-2-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C26H35N3O5S
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0218317
|
N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2,6-dimethyl-N-(oxan-4-ylmethyl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C27H37N3O4S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0511054
|
3-methyl-N,N-dipropyl-2-(2,4,6-trimethylphenoxy)quinolin-5-amine
Show/Hide
|
C25H32N2O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0405100
|
N-(2-cyclopropylethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-yl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C26H35N3O5S
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0459314
|
3-methyl-5-N,5-N-dipropyl-2-N-(2,4,6-trimethylphenyl)quinoline-2,5-diamine
Show/Hide
|
C25H33N3
|
2
|
| 1 |
IC50 = 88 nM
|
|
|
| 2 |
IC50 = 372 nM
|
|
|
|
CP0481598
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-(2-methoxyethyl)-N,3,8-trimethylquinolin-5-amine
Show/Hide
|
C25H32N2O4
|
2
|
| 1 |
IC50 = 89 nM
|
|
|
| 2 |
IC50 = 174 nM
|
|
|
|
CP0433589
|
5-N-(cyclopropylmethyl)-3-methyl-5-N-(oxan-4-yl)-2-N-(2,4,6-trimethylphenyl)quinoline-2,5-diamine
Show/Hide
|
C28H35N3O
|
2
|
| 1 |
IC50 = 90 nM
|
|
|
| 2 |
IC50 = 255 nM
|
|
|
|
CP0513012
|
7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-ethyl-N-(oxan-4-ylmethyl)-N-propylpyrazolo[1,5-a]pyridin-3-amine
Show/Hide
|
C28H39N3O4
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0376563
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine
Show/Hide
|
C25H32N2O4
|
2
|
| 1 |
IC50 = 91 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0520730
|
3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(2-methylpropyl)-N-(oxan-4-yl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
|
C25H35N3O5S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0514859
|
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3-methyl-N,N-dipropylquinolin-5-amine
Show/Hide
|
C26H34N2O3
|
2
|
| 1 |
IC50 = 97 nM
|
|
|
| 2 |
IC50 = 276 nM
|
|
|
|
CP0425433
|
1-[[[7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-methylsulfanylpyrazolo[1,5-a]pyridin-3-yl]-(oxan-4-ylmethyl)amino]methyl]cyclopropan-1-ol
Show/Hide
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C28H37N3O5S
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1
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| 1 |
IC50 = 98 nM
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CP0408775
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3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-yl)-N-propylpyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
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C24H33N3O5S
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1
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| 1 |
IC50 = 98 nM
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CP0377469
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-8-methoxy-3-methyl-N,N-dipropylquinolin-5-amine
Show/Hide
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C27H36N2O4
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2
|
| 1 |
IC50 = 99 nM
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| 2 |
IC50 = 105 nM
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CP0504853
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8-(dipropylamino)-3-(2,4,6-trimethylanilino)-1H-quinoxalin-2-one
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C23H30N4O
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2
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| 1 |
IC50 = 100 nM
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| 2 |
IC50 = 469 nM
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CP0520731
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N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-yl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
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C25H33N3O5S
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1
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| 1 |
IC50 = 101 nM
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CP0524110
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N-(cyclopropylmethyl)-7-(2,6-dimethoxyphenyl)-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
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C27H35N3O3
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1
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| 1 |
IC50 = 105 nM
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CP0424521
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N-(cyclopropylmethyl)-7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-(1,3-dioxan-2-ylmethyl)-2-methylsulfanylpyrazolo[1,5-a]pyridin-3-amine
Show/Hide
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C27H35N3O5S
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1
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| 1 |
IC50 = 113 nM
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CP0481399
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-8-ethyl-3-methyl-N,N-dipropylquinolin-5-amine
Show/Hide
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C28H38N2O3
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2
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| 1 |
IC50 = 115 nM
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| 2 |
IC50 = 375 nM
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CP0545272
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N-(cyclopropylmethyl)-7-[2,4-dimethoxy-6-(methoxymethyl)phenyl]-2-ethyl-N-(oxan-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
Show/Hide
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C29H39N3O4
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1
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| 1 |
IC50 = 120 nM
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CP0448930
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3,5-dimethoxy-4-[6-methoxy-7-[oxan-4-yl(propyl)amino]pyrazolo[5,1-b][1,3]thiazol-3-yl]benzonitrile
Show/Hide
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C23H28N4O4S
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1
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| 1 |
IC50 = 126 nM
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CP0533387
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N-(cyclopropylmethyl)-2-ethyl-N-(oxan-4-ylmethyl)-7-(2,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyridin-3-amine
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C28H37N3O4
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1
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| 1 |
IC50 = 130 nM
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CP0446317
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3-fluoro-8-methylquinolin-5-amine
Show/Hide
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C24H29FN2O3
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2
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| 1 |
IC50 = 131 nM
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| 2 |
IC50 = 144 nM
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CP0511244
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3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(oxan-4-yl)-N-propan-2-ylpyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
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C24H33N3O5S
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1
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| 1 |
IC50 = 136 nM
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CP0450501
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2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-3-methyl-N,N-dipropylquinolin-5-amine
Show/Hide
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C26H34N2O4
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2
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| 1 |
IC50 = 138 nM
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| 2 |
IC50 = 163 nM
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CP0500280
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3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-ethyl-6-methoxy-N-(oxan-4-yl)pyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
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C23H31N3O5S
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1
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| 1 |
IC50 = 147 nM
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CP0523128
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3-methyl-5-N,5-N-dipropyl-2-N-(2,4,6-trimethylphenyl)quinoxaline-2,5-diamine
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C24H32N4
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2
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| 1 |
IC50 = 155 nM
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| 2 |
IC50 = 563 nM
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CP0453644
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N-(cyclopropylmethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-3-methyl-N-(oxan-4-yl)quinolin-5-amine
Show/Hide
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C29H36N2O5
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1
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| 1 |
IC50 = 157 nM
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CP0446316
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methylquinolin-5-amine
Show/Hide
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C24H30N2O3
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2
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| 1 |
IC50 = 184 nM
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| 2 |
IC50 = 381 nM
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CP0504767
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1-[[[7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-methylsulfanylpyrazolo[1,5-a]pyridin-3-yl]-(oxan-4-ylmethyl)amino]methyl]cyclopropane-1-carbonitrile
Show/Hide
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C29H36N4O4S
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1
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| 1 |
IC50 = 194 nM
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CP0514756
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5-N-heptan-4-yl-3-methyl-2-N-(2,4,6-trimethylphenyl)quinoxaline-2,5-diamine
Show/Hide
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C25H34N4
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1
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| 1 |
IC50 = 197 nM
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CP0533388
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[4-[3-[cyclopropylmethyl(oxan-4-ylmethyl)amino]-2-ethylpyrazolo[1,5-a]pyridin-7-yl]-3,5-dimethoxyphenyl]methanol
Show/Hide
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C28H37N3O4
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1
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| 1 |
IC50 = 200 nM
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CP0452226
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxyquinolin-5-amine
Show/Hide
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C24H30N2O4
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2
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| 1 |
IC50 = 202 nM
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| 2 |
IC50 = 332 nM
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CP0438943
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N,3,8-tetramethylquinolin-5-amine
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C23H28N2O3
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2
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| 1 |
IC50 = 212 nM
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| 2 |
IC50 > 1000 nM
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CP0511247
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4-[[cyclopropylmethyl-[3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxypyrazolo[5,1-b][1,3]thiazol-7-yl]amino]methyl]oxan-4-ol
Show/Hide
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C26H35N3O6S
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1
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| 1 |
IC50 = 223 nM
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CP0482639
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4-N-(cyclopropylmethyl)-5-ethylsulfanyl-2-methyl-4-N-propyl-6-N-(2,4,6-trimethylphenyl)pyrimidine-4,6-diamine
Show/Hide
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C23H34N4S
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1
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| 1 |
IC50 = 245.47 nM
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CP0445319
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N-(cyclopropylmethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3,8-dimethyl-N-(oxan-4-yl)quinolin-5-amine
Show/Hide
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C30H38N2O4
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1
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| 1 |
IC50 = 246 nM
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CP0500279
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6-methoxy-3-[2-methoxy-4-(methoxymethyl)phenyl]-N-(oxan-4-yl)-N-propylpyrazolo[5,1-b][1,3]thiazol-7-amine
Show/Hide
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C23H31N3O4S
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1
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| 1 |
IC50 = 254 nM
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CP0446319
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3-methyl-8-(trifluoromethyl)quinolin-5-amine
Show/Hide
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C25H29F3N2O3
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2
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| 1 |
IC50 = 259 nM
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| 2 |
IC50 = 288 nM
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CP0526460
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4-N,4-N-bis(2-methoxyethyl)-2-methyl-5-methylsulfanyl-6-N-(2,4,6-trimethylphenyl)pyrimidine-4,6-diamine
Show/Hide
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C21H32N4O2S
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1
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| 1 |
IC50 = 275.42 nM
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CP0481400
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N-(cyclopropylmethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3,8-dimethyl-N-(oxan-4-ylmethyl)quinolin-5-amine
Show/Hide
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C31H40N2O4
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1
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| 1 |
IC50 = 286 nM
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CP0526931
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2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-N-ethyl-3-methyl-N-(oxan-4-yl)quinolin-5-amine
Show/Hide
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C27H34N2O5
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1
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| 1 |
IC50 = 323 nM
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CP0447856
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-ethyl-8-methoxy-N-(2-methoxyethyl)-3-methylquinolin-5-amine
Show/Hide
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C26H34N2O5
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1
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| 1 |
IC50 = 392 nM
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CP0446320
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8-(difluoromethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3-methylquinolin-5-amine
Show/Hide
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C25H30F2N2O3
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1
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| 1 |
IC50 = 414 nM
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CP0526930
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2-N-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3-methyl-5-N,5-N-dipropylquinoline-2,5-diamine
Show/Hide
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C26H35N3O3
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1
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| 1 |
IC50 = 472 nM
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CP0411729
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5-ethylsulfanyl-2-methyl-4-N,4-N-dipropyl-6-N-(2,4,6-trimethylphenyl)pyrimidine-4,6-diamine
Show/Hide
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C22H34N4S
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1
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| 1 |
IC50 = 537.03 nM
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CP0382345
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5-ethylsulfanyl-4-N,4-N-bis(2-methoxyethyl)-2-methyl-6-N-(2,4,6-trimethylphenyl)pyrimidine-4,6-diamine
Show/Hide
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C22H34N4O2S
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1
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| 1 |
IC50 = 588.84 nM
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CP0437819
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2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-N-ethyl-3-methyl-N-(oxan-4-ylmethyl)quinolin-5-amine
Show/Hide
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C28H36N2O5
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1
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| 1 |
IC50 = 646 nM
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CP0514860
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8-(dipropylamino)-1-methyl-3-(2,4,6-trimethylanilino)quinoxalin-2-one
Show/Hide
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C24H32N4O
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1
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| 1 |
IC50 = 672 nM
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CP0438376
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5-N-(cyclopropylmethyl)-3-methyl-5-N-(oxan-4-ylmethyl)-2-N-(2,4,6-trimethylphenyl)quinoline-2,5-diamine
Show/Hide
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C29H37N3O
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1
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| 1 |
IC50 = 742 nM
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CP0509769
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N-(cyclopropylmethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-3-methyl-N-(oxan-4-ylmethyl)quinolin-5-amine
Show/Hide
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C30H38N2O5
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1
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| 1 |
IC50 = 762 nM
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CP0437818
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3-methyl-5-N,5-N-dipropyl-2-N-(2,4,6-trimethoxyphenyl)quinoline-2,5-diamine
Show/Hide
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C25H33N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0438377
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2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-3-methyl-N-pentan-3-ylquinolin-5-amine
Show/Hide
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C25H32N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0467395
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N-cyclohexyl-2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-3-methylquinolin-5-amine
Show/Hide
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C26H32N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0484732
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8-(dipropylamino)-1-methyl-3-(N,2,4,6-tetramethylanilino)quinoxalin-2-one
Show/Hide
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C25H34N4O
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1
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| 1 |
IC50 > 1000 nM
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CP0484733
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2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-N-ethyl-3-methyl-N-(pyridin-4-ylmethyl)quinolin-5-amine
Show/Hide
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C28H31N3O4
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1
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| 1 |
IC50 > 1000 nM
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CP0412576
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2-[2,6-dimethoxy-4-(methoxymethyl)phenoxy]-3,8-dimethyl-N,N-dipropylquinolin-5-amine
Show/Hide
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C27H36N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0450502
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3,8-dimethyl-N-pentan-3-ylquinolin-5-amine
Show/Hide
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C26H34N2O3
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1
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| 1 |
IC50 > 1000 nM
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CP0481402
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-(2-methoxyethyl)-3,8-dimethylquinolin-5-amine
Show/Hide
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C24H30N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0377470
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2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-(methoxymethyl)-3-methylquinolin-5-amine
Show/Hide
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C26H34N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0384222
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N,N-dibutyl-3-(2,4-dichlorophenyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C22H28Cl2N4
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1
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| 1 |
Ki = 0.62 nM
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CP0541373
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-pentyl-amine
Show/Hide
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C23H30Cl2N4
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1
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| 1 |
Ki = 0.9 nM
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CP0467983
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N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-N-hexyl-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C24H30Cl2N4
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1
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| 1 |
Ki = 1 nM
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CP0507239
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3-(2,4-dichlorophenyl)-1,5-dimethyl-N-pentyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C22H28Cl2N4
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1
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| 1 |
Ki = 1.2 nM
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CP0443768
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Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-amine
Show/Hide
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C22H26Cl2N4
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1
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| 1 |
Ki = 1.3 nM
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CP0534357
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3-(2,4-dichlorophenyl)-N-ethyl-1,5-dimethyl-N-pentylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C21H26Cl2N4
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1
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| 1 |
Ki = 1.3 nM
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CP0534363
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(2-methylsulfanyl-ethyl)-amine
Show/Hide
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C21H26Cl2N4S
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1
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| 1 |
Ki = 1.4 nM
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CP0467132
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9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-8-methoxy-2-methylpurin-6-amine
Show/Hide
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C22H30BrN5O
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1
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| 1 |
Ki = 1.5 nM
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CP0510349
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9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-8-chloro-N-ethyl-2-methylpurin-6-amine
Show/Hide
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C21H27BrClN5
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1
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| 1 |
Ki = 1.5 nM
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CP0452981
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N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-1,5-dimethyl-N-pentylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C23H28Cl2N4
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1
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| 1 |
Ki = 1.5 nM
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CP0507461
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N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-1,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C21H24Cl2N4
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1
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| 1 |
Ki = 1.7 nM
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CP0377837
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine
Show/Hide
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C20H24Cl2N4
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1
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| 1 |
Ki = 2 nM
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CP0407409
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N,N-dibutyl-3-(2-chloro-4,6-dimethylphenyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C24H33ClN4
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1
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| 1 |
Ki = 2.1 nM
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CP0534364
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N,N-dibutyl-3-(2-chloro-4-methylphenyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C23H31ClN4
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1
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| 1 |
Ki = 2.8 nM
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CP0562197
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7-(Butyl-ethyl-amino)-1,5-dimethyl-3-phenyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one
Show/Hide
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C23H31BrN4O
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1
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| 1 |
Ki = 3 nM
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CP0452935
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3-(2,4-dichlorophenyl)-N-ethyl-N-(2-methoxyethyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C19H22Cl2N4O
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1
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| 1 |
Ki = 3.2 nM
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CP0453628
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3-(2,4-dichlorophenyl)-1,5-dimethyl-N,N-dipropylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C20H24Cl2N4
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1
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| 1 |
Ki = 3.3 nM
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CP0463300
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N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-1,5-dimethyl-N-(2-methylpropyl)pyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C22H26Cl2N4
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1
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| 1 |
Ki = 3.7 nM
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CP0374629
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3-(2,4-dichlorophenyl)-N-hexyl-N-(2-methoxyethyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C23H30Cl2N4O
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1
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| 1 |
Ki = 4 nM
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CP0310325
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3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione
Show/Hide
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C19H23BrN4S2
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1
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| 1 |
Ki = 4.1 nM
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CP0512446
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3-(2-Bromo-4-isopropyl-phenyl)-7-(cyclopropylmethyl-propyl-amino)-5-methyl-3H-thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
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C22H27BrN4OS
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1
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| 1 |
Ki = 4.1 nM
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CP0511096
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3-(2,4-dichlorophenyl)-N-ethyl-1,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C19H22Cl2N4
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1
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| 1 |
Ki = 4.1 nM
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CP0409186
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6-(Butyl-ethyl-amino)-2,7-dimethyl-9-(2,4,6-trimethyl-phenyl)-7,9-dihydro-purin-8-one
Show/Hide
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C22H31N5O
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1
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| 1 |
Ki = 4.4 nM
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CP0470963
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2-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-propyl-amino}-ethanol
Show/Hide
|
C19H22Cl2N4O
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1
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| 1 |
Ki = 4.4 nM
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CP0496312
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N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-N-ethyl-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
|
C20H22Cl2N4
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1
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| 1 |
Ki = 4.4 nM
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CP0377803
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N,N-dibutyl-3-(2-chloro-4-methoxyphenyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
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C23H31ClN4O
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1
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| 1 |
Ki = 4.8 nM
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CP0274618
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9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amino)-2,7-dimethyl-7,9-dihydro-purin-8-one
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C22H30BrN5O
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1
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| 1 |
Ki = 5 nM
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CP0418870
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7-[Bis-(2-methoxy-ethyl)-amino]-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidin-2-one
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C21H28N4O3S
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1
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| 1 |
Ki = 5 nM
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CP0509981
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3-(2,4-dichlorophenyl)-N-(2-methoxyethyl)-1,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
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C20H24Cl2N4O
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1
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| 1 |
Ki = 5.1 nM
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CP0554900
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N,N-dibutyl-1,5-dimethyl-3-(2,4,6-trimethylphenyl)pyrazolo[4,3-b]pyridin-7-amine
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C25H36N4
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1
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| 1 |
Ki = 5.1 nM
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CP0536613
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9-(2-Bromo-4-isopropyl-phenyl)-6-(cyclopropylmethyl-propyl-amino)-2,7-dimethyl-7,9-dihydro-purin-8-one
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C23H30BrN5O
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1
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| 1 |
Ki = 5.7 nM
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CP0449655
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6-(Cyclopropylmethyl-propyl-amino)-2,7-dimethyl-9-(2,4,6-trimethyl-phenyl)-7,9-dihydro-purin-8-one
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C23H31N5O
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1
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| 1 |
Ki = 6.1 nM
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CP0431132
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7-[Bis-(2-methoxy-ethyl)-amino]-3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione
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C21H27BrN4O2S2
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1
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| 1 |
Ki = 6.6 nM
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CP0461462
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3-(2,4-dichlorophenyl)-N-(2-methoxyethyl)-1,5-dimethyl-N-pentylpyrazolo[4,3-b]pyridin-7-amine
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C22H28Cl2N4O
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1
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| 1 |
Ki = 6.7 nM
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CP0511402
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N-butyl-3-(2,4-dichlorophenyl)-1,5-dimethyl-N-pentan-3-ylpyrazolo[4,3-b]pyridin-7-amine
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C23H30Cl2N4
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1
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| 1 |
Ki = 7 nM
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CP0409405
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9-(2-Bromo-4-isopropyl-phenyl)-6-dipropylamino-2,7-dimethyl-7,9-dihydro-purin-8-one
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C22H30BrN5O
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1
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| 1 |
Ki = 7.6 nM
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CP0463539
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3-(2,4-dichlorophenyl)-N,N-bis(2-methoxyethyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
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C20H24Cl2N4O2
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1
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| 1 |
Ki = 8.2 nM
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CP0506157
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7-[Bis-(2-methoxy-ethyl)-amino]-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidine-2-thione
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C21H28N4O2S2
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1
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| 1 |
Ki = 8.6 nM
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CP0442058
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7-Diethylamino-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidine-2-thione
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C19H24N4S2
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1
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| 1 |
Ki = 9.2 nM
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CP0182111
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3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-methyl-3H-thiazolo[4,5-d]pyrimidin-2-one
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C19H23BrN4OS
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1
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| 1 |
Ki = 9.4 nM
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CP0476938
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3-(2,4-dichlorophenyl)-N-(2-methoxyethyl)-1,5-dimethyl-N-propan-2-ylpyrazolo[4,3-b]pyridin-7-amine
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C20H24Cl2N4O
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1
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| 1 |
Ki = 9.7 nM
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CP0463540
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3-(2,4-dichlorophenyl)-N-(3-methoxypropyl)-1,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
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C21H26Cl2N4O
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1
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| 1 |
Ki = 9.8 nM
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CP0448283
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(2-methoxy-ethyl)-amine
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C21H26Cl2N4O
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1
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| 1 |
Ki = 10.4 nM
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CP0507555
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3-(2,4-dichlorophenyl)-N-(2-methoxyethyl)-1,5-dimethyl-N-(2-methylpropyl)pyrazolo[4,3-b]pyridin-7-amine
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C21H26Cl2N4O
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1
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| 1 |
Ki = 10.5 nM
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CP0448563
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(tetrahydro-furan-2-ylmethyl)-amine
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C23H28Cl2N4O
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1
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| 1 |
Ki = 11.2 nM
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CP0409692
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9-(2-Bromo-4-isopropyl-phenyl)-6-[cyclopropylmethyl-(2-methoxy-ethyl)-amino]-2,7-dimethyl-7,9-dihydro-purin-8-one
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C23H30BrN5O2
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1
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| 1 |
Ki = 12.2 nM
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CP0463109
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3-(2,4-dichlorophenyl)-N-ethyl-N-(3-methoxypropyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
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C20H24Cl2N4O
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1
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| 1 |
Ki = 12.5 nM
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CP0503034
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3-(2-Bromo-4-isopropyl-phenyl)-7-(cyclopropylmethyl-propyl-amino)-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione
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C22H27BrN4S2
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1
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| 1 |
Ki = 12.6 nM
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CP0460744
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(2-pyridin-2-yl-ethyl)-amine
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C25H27Cl2N5
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1
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| 1 |
Ki = 13 nM
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CP0463340
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4-({[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-propyl-amino}-methyl)-phenol
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C24H24Cl2N4O
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1
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| 1 |
Ki = 13 nM
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CP0439562
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7-(Cyclopropylmethyl-propyl-amino)-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidine-2-thione
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C22H28N4S2
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1
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| 1 |
Ki = 13.1 nM
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CP0496327
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7-Diethylamino-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidin-2-one
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C19H24N4OS
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1
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| 1 |
Ki = 14.5 nM
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CP0498148
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7-[Bis-(2-methoxy-ethyl)-amino]-3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
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C21H27BrN4O3S
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1
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| 1 |
Ki = 14.5 nM
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CP0391253
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9-(2-Bromo-4-isopropyl-phenyl)-6-(1-ethyl-pentylamino)-2,7-dimethyl-7,9-dihydro-purin-8-one
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C23H32BrN5O
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1
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| 1 |
Ki = 15.1 nM
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CP0405335
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7-(Cyclopropylmethyl-propyl-amino)-5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-thiazolo[4,5-d]pyrimidin-2-one
Show/Hide
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C22H28N4OS
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1
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| 1 |
Ki = 16.2 nM
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CP0437432
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6-(1-Ethyl-pentylamino)-2,7-dimethyl-9-(2,4,6-trimethyl-phenyl)-7,9-dihydro-purin-8-one
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C23H33N5O
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1
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| 1 |
Ki = 17.4 nM
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CP0449134
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(3-methoxy-propyl)-amine
Show/Hide
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C22H28Cl2N4O
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1
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| 1 |
Ki = 18 nM
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CP0492136
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3-(2-Bromo-4-isopropyl-phenyl)-7-(butyl-ethyl-amino)-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione
Show/Hide
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C21H27BrN4S2
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1
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| 1 |
Ki = 23.9 nM
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CP0460332
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3-(2,4-dichlorophenyl)-N,1,5-trimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
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C18H20Cl2N4
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1
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| 1 |
Ki = 24 nM
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CP0497778
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6-[Benzyl-(2-methoxy-ethyl)-amino]-9-(2-bromo-4-isopropyl-phenyl)-2,7-dimethyl-7,9-dihydro-purin-8-one
Show/Hide
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C26H30BrN5O2
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1
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| 1 |
Ki = 26.2 nM
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CP0528762
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9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-8-(cyclopropylmethoxy)-N-ethyl-2-methylpurin-6-amine
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C25H34BrN5O
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1
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| 1 |
Ki = 31.1 nM
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CP0507355
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3-(2,4-dichlorophenyl)-N-(2-methoxyethyl)-N,1,5-trimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C18H20Cl2N4O
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1
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| 1 |
Ki = 32 nM
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CP0407106
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(2-pyridin-4-yl-ethyl)-amine
Show/Hide
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C25H27Cl2N5
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1
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| 1 |
Ki = 34 nM
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CP0391254
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9-(2-Bromo-4-isopropyl-phenyl)-6-(1-methoxymethyl-propylamino)-2,7-dimethyl-7,9-dihydro-purin-8-one
Show/Hide
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C21H28BrN5O2
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1
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| 1 |
Ki = 42.8 nM
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CP0509178
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3-(2-Bromo-4-isopropyl-phenyl)-7-(di-sec-butyl-amino)-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione
Show/Hide
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C23H31BrN4S2
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1
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| 1 |
Ki = 45.4 nM
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CP0494144
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9-(2-Bromo-4-isopropyl-phenyl)-6-[ethyl-(2-methoxy-ethyl)-amino]-2,7-dimethyl-7,9-dihydro-purin-8-one
Show/Hide
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C21H28BrN5O2
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1
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| 1 |
Ki = 47.9 nM
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CP0461463
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2-[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-ylamino]-pentan-1-ol
Show/Hide
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C19H22Cl2N4O
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1
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| 1 |
Ki = 62 nM
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CP0503442
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-pyridin-4-ylmethyl-amine
Show/Hide
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C24H25Cl2N5
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1
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| 1 |
Ki = 68 nM
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CP0527693
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6-(Cyclopropylmethyl-propyl-amino)-2,7-dimethyl-9-(2,4,6-trimethyl-pyridin-3-yl)-7,9-dihydro-purin-8-one
Show/Hide
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C22H30N6O
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1
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| 1 |
Ki = 113 nM
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CP0432912
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9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amino)-7-cyclopropylmethyl-2-methyl-7,9-dihydro-purin-8-one
Show/Hide
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C25H34BrN5O
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1
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| 1 |
Ki = 117 nM
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CP0530246
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3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-7-morpholin-4-yl-3H-thiazolo[4,5-d]pyrimidine-2-thione
Show/Hide
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C19H21BrN4OS2
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1
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| 1 |
Ki = 122 nM
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CP0496989
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6-(Butyl-ethyl-amino)-2,7-dimethyl-9-(2,4,6-trimethyl-pyridin-3-yl)-7,9-dihydro-purin-8-one
Show/Hide
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C21H30N6O
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1
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| 1 |
Ki = 124 nM
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CP0508550
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6-[Bis-(2-methoxy-ethyl)-amino]-9-(2-bromo-4-isopropyl-phenyl)-2,7-dimethyl-7,9-dihydro-purin-8-one
Show/Hide
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C22H30BrN5O3
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1
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| 1 |
Ki = 130 nM
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CP0534459
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-amine
Show/Hide
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C18H20Cl2N4
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1
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| 1 |
Ki = 170 nM
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CP0536913
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6-Dipropylamino-2,7-dimethyl-9-(2,4,6-trimethyl-pyridin-3-yl)-7,9-dihydro-purin-8-one
Show/Hide
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C21H30N6O
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1
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| 1 |
Ki = 259 nM
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CP0463336
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N,N-dibutyl-3-(4-chlorophenyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
Show/Hide
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C22H29ClN4
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1
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| 1 |
Ki = 340 nM
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CP0479721
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9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-2-methyl-8-morpholin-4-ylpurin-6-amine
Show/Hide
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C25H35BrN6O
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1
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| 1 |
Ki = 345 nM
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CP0438478
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Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-(1-methyl-pyrrolidin-2-ylmethyl)-amine
Show/Hide
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C24H31Cl2N5
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1
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| 1 |
Ki = 380 nM
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CP0453544
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4-(Butyl-ethyl-amino)-3,6-dimethyl-1-phenyl-1,3-dihydro-imidazo[4,5-c]pyridin-2-one
Show/Hide
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C23H31BrN4O
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1
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| 1 |
Ki = 463 nM
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CP0419734
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6-[Bis-(2-methoxy-ethyl)-amino]-2,7-dimethyl-9-(2,4,6-trimethyl-phenyl)-7,9-dihydro-purin-8-one
Show/Hide
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C22H31N5O3
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1
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| 1 |
Ki = 698 nM
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CP0529583
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9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amino)-2-methyl-7,9-dihydro-purin-8-one
Show/Hide
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C21H28BrN5O
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1
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| 1 |
Ki = 890 nM
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CP0412216
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9-(2-Bromo-4-isopropyl-phenyl)-6-(2-methoxy-ethylamino)-2,7-dimethyl-7,9-dihydro-purin-8-one
Show/Hide
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C19H24BrN5O2
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1
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| 1 |
Ki = 1179 nM
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CP0402875
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4-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-ylamino]-methyl}-phenol
Show/Hide
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C21H18Cl2N4O
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1
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| 1 |
Ki > 10000 nM
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