Brief Information of the Compound and Protein
Compound Name
5-ethylsulfanyl-4-N,4-N-bis(2-methoxyethyl)-2-methyl-6-N-(2,4,6-trimethylphenyl)pyrimidine-4,6-diamine
    Show/Hide
PubChem ID
CID: 90654668
Canonical SMILES
CCSc1c(Nc2c(C)cc(C)cc2C)nc(C)nc1N(CCOC)CCOC
    Show/Hide
Compound Formula C22H34N4O2S
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 588.84 nM
   TI
   LI
   LO
   TS