Brief Information of the Compound and Protein
Compound Name
5-ethylsulfanyl-2-methyl-4-N,4-N-dipropyl-6-N-(2,4,6-trimethylphenyl)pyrimidine-4,6-diamine
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PubChem ID
CID: 90654667
Canonical SMILES
CCCN(CCC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SCC
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Compound Formula C22H34N4S
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 537.03 nM
   TI
   LI
   LO
   TS