Brief Information of the Compound and Protein
Compound Name
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-ethyl-N-(2-methoxyethyl)-3,8-dimethylquinolin-5-amine
    Show/Hide
PubChem ID
CID: 70690704
SID: 163453416
Canonical SMILES
CCN(CCOC)c1ccc(C)c2nc(c(C)cc12)-c1c(OC)cc(COC)cc1OC
    Show/Hide
Compound Formula C26H34N2O4
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
2
IC50 = 109 nM
   TI
   LI
   LO
   TS