Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-N-(cyclopropylmethyl)-3-methyl-5-N-(oxan-4-yl)-2-N-(2,4,6-trimethylphenyl)quinoline-2,5-diamine
    Show/Hide
 PubChem ID
CID: 70690481
SID: 163441224
Canonical SMILES
Cc1cc(C)c(Nc2nc3cccc(N(CC4CC4)C4CCOCC4)c3cc2C)c(C)c1
    Show/Hide
Compound Formula C28H35N3O
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
2
IC50 = 255 nM
   TI
   LI
   LO
   TS