Brief Information of the Compound and Protein
Compound Name
N,N-bis(cyclopropylmethyl)-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-3,8-dimethylquinolin-5-amine
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PubChem ID
CID: 70692846
SID: 163453414
Canonical SMILES
COCc1cc(OC)c(c(OC)c1)-c1nc2c(C)ccc(N(CC3CC3)CC3CC3)c2cc1C
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Compound Formula C29H36N2O3
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
2
IC50 = 88 nM
   TI
   LI
   LO
   TS