Brief Information of the Compound and Protein
Compound Name
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N-(2-methoxyethyl)-N,3,8-trimethylquinolin-5-amine
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PubChem ID
CID: 70684375
SID: 163453415
Canonical SMILES
COCCN(C)c1ccc(C)c2nc(c(C)cc12)-c1c(OC)cc(COC)cc1OC
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Compound Formula C25H32N2O4
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 89 nM
   TI
   LI
   LO
   TS
2
IC50 = 174 nM
   TI
   LI
   LO
   TS