Brief Information of the Compound and Protein
Compound Name
N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-1,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
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PubChem ID
CID: 9952997
SID: 14928403
Canonical SMILES
CCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl
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Compound Formula C21H24Cl2N4
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000809 HEK273 Homo sapiens (Human)  1
1
Ki = 1.7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1.7 nM
   TI
   LI
   LO
   TS
CL000041 LTK- Mus musculus (Mouse)  1
1
Ki = 1.585 nM
   TI
   LI
   LO
   TS