Brief Information of the Compound and Protein
Compound Name
2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N,3,8-tetramethylquinolin-5-amine
    Show/Hide
PubChem ID
CID: 70690703
SID: 163453412
Canonical SMILES
COCc1cc(OC)c(c(OC)c1)-c1nc2c(C)ccc(N(C)C)c2cc1C
    Show/Hide
Compound Formula C23H28N2O3
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 212 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS