Brief Information of the Compound and Protein
Compound Name
4-[5-(diethylamino)-8-methoxy-3-methylquinolin-2-yl]-3,5-dimethoxybenzonitrile
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PubChem ID
CID: 71451515
SID: 163447732
Canonical SMILES
CCN(CC)c1ccc(OC)c2nc(c(C)cc12)-c1c(OC)cc(cc1OC)C#N
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Compound Formula C24H27N3O3
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 63 nM
   TI
   LI
   LO
   TS
2
IC50 = 132 nM
   TI
   LI
   LO
   TS