| Compound ID |
Compound Name |
Compound Formula |
|
CP0015142
|
[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]-4-(naphthalene-1-carbonyloxy)oxolan-3-yl] naphthalene-1-carboxylate
Show/Hide
|
C32H28N5O15P3
|
3
|
| 1 |
EC50 = 16595.87 nM
|
|
|
| 2 |
EC50 = 22387.21 nM
|
|
|
| 3 |
IC50 > 100000 nM
|
|
|
|
CP0015141
|
[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-benzoyloxy-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-yl] benzoate
Show/Hide
|
C24H24N5O15P3
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0389792
|
[4-[3-[1-[4-(dimethylamino)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H31N5O4S
|
1
|
| 1 |
IC50 = 0.11 nM
|
|
|
|
CP0189544
|
N-(1-adamantylmethyl)-2-chloro-5-[3-(3-hydroxypropylamino)propyl]benzamide;hydrochloride
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|
C24H36Cl2N2O2
|
1
|
| 1 |
IC50 = 0.23 nM
|
|
|
|
CP0455718
|
[4-[3-[1-[4-(dimethylamino)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-(cyclopropylcarbamoyl)benzenesulfonate
Show/Hide
|
C33H35N5O5S
|
1
|
| 1 |
IC50 = 0.49 nM
|
|
|
|
CP0874960
|
(S)-5-(1-(3-amino-2-hydroxypropyl)-5-methyl-1H-pyrazol-3-yl)-2-chloro-N-((1-hydroxycycloheptyl)methyl)benzamide hydrochloride
Show/Hide
|
C22H32Cl2N4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0373635
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-1,3-dimethyl-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C14H15ClF3N3O2
|
1
|
| 1 |
IC50 = 0.631 nM
|
|
|
|
CP0136276
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-[4-[(2R)-2-hydroxy-3-methoxypropyl]-3,5-dioxo-1,2,4-triazin-2-yl]benzamide
Show/Hide
|
C22H29ClN4O6
|
2
|
| 1 |
IC50 = 0.76 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0468749
|
[4-[3-[1-(4-nitrobenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C30H25N5O6S
|
1
|
| 1 |
IC50 = 1.49 nM
|
|
|
|
CP0413634
|
US9409917, 22
Show/Hide
|
C17H16Cl2N2O2
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0865073
|
N-Adamantan-2-ylmethyl-2-chloro-5-[3-(3-hydroxy-propylamino)-propyl]-benzamide hydrochloride
Show/Hide
|
C24H36Cl2N2O2
|
2
|
| 1 |
IC50 = 1.5 nM
|
|
|
| 2 |
IC50 = 2 nM
|
|
|
|
CP0451123
|
[4-[[6-[4-[4-(dimethylamino)benzoyl]piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H32N6O6S
|
1
|
| 1 |
IC50 = 1.53 nM
|
|
|
|
CP0526472
|
(4S)-N-[(2,4-dichlorophenyl)methyl]-1,3-dimethyl-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C13H15Cl2N3O2
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0388229
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(1-methylimidazol-4-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C17H17ClF3N5O2
|
1
|
| 1 |
IC50 = 2.512 nM
|
|
|
|
CP0545003
|
US9409917, 40
Show/Hide
|
C17H14ClF3N2O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0468602
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-(5-methyl-1H-pyrazol-3-yl)benzamide
Show/Hide
|
C19H24ClN3O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0915351
|
(R)-5-(1-(3-amino-2-hydroxypropyl)-5-methyl-1H-pyrazol-3-yl)-2-chloro-N-((1-hydroxycycloheptyl)methyl)benzamide hydrochloride
Show/Hide
|
C22H32Cl2N4O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0457961
|
2-(1-adamantyl)-N-[2-[4-(hydroxymethyl)phenyl]quinolin-5-yl]acetamide
Show/Hide
|
C28H30N2O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0379792
|
US9409917, 12
Show/Hide
|
C17H15Cl2FN2O2
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0231462
|
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-1-methyl-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C14H14ClF3N2O2
|
5
|
| 1 |
IC50 = 3.162 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
| 3 |
IC50 = 119.3 nM
|
|
|
| 4 |
IC50 = 332.4 nM
|
|
|
| 5 |
Ki = 68 nM
|
|
|
|
CP0543669
|
AZD-9056
Show/Hide
|
C24H35ClN2O2
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0356358
|
6-chloro-2-[3-(dimethylamino)pyrrolidin-1-yl]-N-[[(1S,3R)-1-hydroxy-3-methylcyclohexyl]methyl]quinoline-5-carboxamide
Show/Hide
|
C24H33ClN4O2
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0386140
|
(3S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-4-methyl-5-oxomorpholine-3-carboxamide
Show/Hide
|
C14H14ClF3N2O3
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0472720
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C13H13ClF3N3O2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0509557
|
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-4,4-difluoro-1-methyl-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C14H12ClF5N2O2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0526471
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(1-methylimidazol-2-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C17H17ClF3N5O2
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0392863
|
2-(1-adamantyl)-N-(2-chloroquinolin-5-yl)acetamide
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0177578
|
6-chloro-2-[(3R)-3-fluoropyrrolidin-1-yl]-N-[[(1S,3S)-1-hydroxy-3-methylcyclohexyl]methyl]quinoline-5-carboxamide
Show/Hide
|
C22H27ClFN3O2
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0513060
|
US9409917, 11
Show/Hide
|
C16H13Cl2FN2O2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0399443
|
4-bromo-N'-(3,5-dichloropyridin-4-yl)adamantane-2-carbohydrazide
Show/Hide
|
C16H18BrCl2N3O
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0249336
|
6-chloro-N-[(3,3-difluorocyclohexyl)methyl]-2-[(3R)-3-fluoropyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C21H23ClF3N3O
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0479123
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(2-methylpyridin-3-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C19H18ClF3N4O2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0123319
|
1-(4-chlorophenyl)-4-(ethoxymethyl)triazole
Show/Hide
|
C11H12ClN3O
|
2
|
| 1 |
IC50 = 5.3 nM
|
|
|
| 2 |
IC50 = 67 nM
|
|
|
|
CP0520236
|
BDBM199009
Show/Hide
|
C16H12ClF3N2O2
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0495551
|
US9409917, 51
Show/Hide
|
C17H16Cl2N2O3
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0498821
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-(2-methyl-1,3-thiazol-4-yl)benzamide
Show/Hide
|
C19H23ClN2O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0577860
|
US9409917, 19
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0389813
|
methyl 4-[5-[[2-(1-adamantyl)acetyl]amino]quinolin-2-yl]benzoate
Show/Hide
|
C29H30N2O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0451124
|
[2-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]-3H-benzimidazol-5-yl] isoquinoline-5-sulfonate
Show/Hide
|
C29H26N4O6S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0493196
|
US9409917, 67
Show/Hide
|
C21H22ClF2N3O2
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0269198
|
N-[(2,4-dichlorophenyl)methyl]-2-(3,5-dimethyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C14H15Cl2N3O
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0528340
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-methylpyrimidin-2-yl)benzamide
Show/Hide
|
C20H24ClN3O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0389818
|
4-[5-[[2-(1-adamantyl)acetyl]amino]quinolin-2-yl]benzoic acid
Show/Hide
|
C28H28N2O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0426452
|
2-(1-adamantyl)-N-[2-(4-hydroxyphenyl)quinolin-5-yl]acetamide
Show/Hide
|
C27H28N2O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0145465
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-[(3S)-3-fluoropyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C21H23ClF3N3O
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0435266
|
N-[1-[[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
Show/Hide
|
C26H28N6O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0445443
|
N-[1-[(Z)-[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(4-methylsulfanylphenyl)acetamide
Show/Hide
|
C25H28N6OS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0537882
|
2-(4-chlorophenyl)-N-[1-[[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]acetamide
Show/Hide
|
C24H25ClN6O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0409280
|
(4S)-N-[(2,4-dichlorophenyl)methyl]-3-methyl-1-(2-methylpyridin-3-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C18H18Cl2N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0428280
|
(4S)-N-[(2,4-dichlorophenyl)methyl]-3-methyl-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C12H13Cl2N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0509556
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(2-methylpyridin-4-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C19H18ClF3N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0511733
|
(4S)-N-[(2,3-dichlorophenyl)methyl]-1,3-dimethyl-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C13H15Cl2N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0206765
|
(2,3-dichlorophenyl)-(3-pyrazin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C16H12Cl2N6O
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0253003
|
[2-chloro-3-(trifluoromethyl)phenyl]-[3-(4-fluorophenyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C19H13ClF4N4O
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0541481
|
2-(1-adamantyl)-N-[2-(4-aminophenyl)quinolin-5-yl]acetamide
Show/Hide
|
C27H29N3O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0557985
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-[3-(2-hydroxyethylamino)pyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C23H29ClF2N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0517251
|
US9409917, 34
Show/Hide
|
C16H14Cl2N2O2
|
1
|
| 1 |
IC50 = 10.7 nM
|
|
|
|
CP0451524
|
US9409917, 93
Show/Hide
|
C18H18Cl2N2O4
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
|
CP0509555
|
1-(2,3-dichlorophenyl)-N-[(2-methylsulfonylphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5O2S
|
1
|
| 1 |
IC50 = 11.48 nM
|
|
|
|
CP0490247
|
US9409917, 39
Show/Hide
|
C16H14Cl2N2O2
|
1
|
| 1 |
IC50 = 11.8 nM
|
|
|
|
CP0468600
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-(1H-pyrazol-5-yl)benzamide
Show/Hide
|
C18H22ClN3O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0542887
|
N-[(2S)-2-(4-chlorophenyl)-2-morpholin-4-ylethyl]-2-pyrimidin-2-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C21H19ClF3N5O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0422191
|
N-[2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C21H21FN4O3S
|
1
|
| 1 |
IC50 = 12.1 nM
|
|
|
|
CP0490245
|
US9409917, 23
Show/Hide
|
C17H14Cl2N2O2
|
1
|
| 1 |
IC50 = 12.2 nM
|
|
|
|
CP0409247
|
US9409917, 114
Show/Hide
|
C15H11Cl3N2O2
|
1
|
| 1 |
IC50 = 12.5 nM
|
|
|
|
CP0544917
|
US9409917, 16
Show/Hide
|
C16H12ClF3N2O2
|
1
|
| 1 |
IC50 = 12.6 nM
|
|
|
|
CP0507326
|
US9409917, 21
Show/Hide
|
C18H16Cl2N2O2
|
1
|
| 1 |
IC50 = 12.9 nM
|
|
|
|
CP0378096
|
N'-(3,5-dichloropyridin-4-yl)-3,5-dimethyladamantane-1-carbohydrazide
Show/Hide
|
C18H23Cl2N3O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0451119
|
[2-[1-(4-nitrobenzoyl)piperidin-4-yl]-3H-benzimidazol-5-yl] isoquinoline-5-sulfonate
Show/Hide
|
C28H23N5O6S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0509276
|
1-(2,3-dichlorophenyl)-N-[(2-methoxyphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5O
|
1
|
| 1 |
IC50 = 13.8 nM
|
|
|
|
CP0428806
|
US9409917, 68
Show/Hide
|
C16H11Cl2F3N2O2
|
1
|
| 1 |
IC50 = 13.8 nM
|
|
|
|
CP0391492
|
[4-[[6-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H37N5O6S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0537517
|
6-chloro-N-[[(1S,3R)-1-hydroxy-3-methylcyclohexyl]methyl]-2-[(3R)-3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C25H34ClN3O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0441353
|
N-benzyl-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C14H11Cl2N5
|
1
|
| 1 |
IC50 = 14.45 nM
|
|
|
|
CP0539966
|
US9409917, 72
Show/Hide
|
C17H16Cl2N2O3
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0422018
|
1-(2,3-dichlorophenyl)-N-[(2,3-dimethoxyphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C16H15Cl2N5O2
|
1
|
| 1 |
IC50 = 14.79 nM
|
|
|
|
CP0470271
|
N-(1,3-benzodioxol-4-ylmethyl)-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C15H11Cl2N5O2
|
1
|
| 1 |
IC50 = 14.79 nM
|
|
|
|
CP0526470
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-2-oxo-1,3-oxazolidine-4-carboxamide
Show/Hide
|
C13H12ClF3N2O3
|
2
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0460705
|
1-(2,3-dichlorophenyl)-N-[(1R)-2,3-dihydro-1H-inden-1-yl]tetrazol-5-amine
Show/Hide
|
C16H13Cl2N5
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0153595
|
N-[[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methyl]-2-phenylsulfanylpyridine-3-carboxamide
Show/Hide
|
C28H32N4O2S
|
2
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0377020
|
2-chloro-5-(5-fluoropyrimidin-2-yl)-N-((1-hydroxycycloheptyl)methyl)benzamide
Show/Hide
|
C19H21ClFN3O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0409308
|
US9409917, 31
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0409309
|
US9409917, 41
Show/Hide
|
C17H16Cl2N2O3
|
1
|
| 1 |
IC50 = 16.3 nM
|
|
|
|
CP0494400
|
1-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5
|
1
|
| 1 |
IC50 = 16.6 nM
|
|
|
|
CP0502619
|
1-(2,3-dichlorophenyl)-N-(2-methylphenyl)tetrazol-5-amine
Show/Hide
|
C14H11Cl2N5
|
1
|
| 1 |
IC50 = 16.6 nM
|
|
|
|
CP0502310
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-(hydroxymethyl)pyridin-2-yl)benzamide
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0514138
|
2-chloro-N-((2-fluoro-1-hydroxycycloheptyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide
Show/Hide
|
C19H20ClF2N3O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0404877
|
5-(2,3-dichlorophenyl)-1-[(2-methylphenyl)methyl]tetrazole
Show/Hide
|
C15H12Cl2N4
|
1
|
| 1 |
IC50 = 17.78 nM
|
|
|
|
CP0528339
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(6-methylpyridazin-3-yl)benzamide
Show/Hide
|
C20H24ClN3O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0466664
|
2-(1-adamantyl)-N-[2-(4-methoxyphenyl)quinolin-5-yl]acetamide
Show/Hide
|
C28H30N2O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0145467
|
6-chloro-N-[(3,3-difluoro-1-hydroxycyclohexyl)methyl]-2-[(3S)-3-fluoropyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C21H23ClF3N3O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0476845
|
2-[[[1-(2,3-dichlorophenyl)tetrazol-5-yl]amino]methyl]benzonitrile
Show/Hide
|
C15H10Cl2N6
|
1
|
| 1 |
IC50 = 18.2 nM
|
|
|
|
CP0494399
|
1-(2,3-dichlorophenyl)-N-[(2-fluorophenyl)methyl]tetrazol-5-amine
Show/Hide
|
C14H10Cl2FN5
|
1
|
| 1 |
IC50 = 18.2 nM
|
|
|
|
CP0202741
|
6-chloro-N-[[(1S)-3,3-difluoro-1-hydroxycyclohexyl]methyl]-2-[(3R)-3-fluoropyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C21H23ClF3N3O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0482752
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-[(3R)-3-fluoropyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C21H23ClF3N3O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0435264
|
N-[1-[[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-2-(4-methylsulfanylphenyl)acetamide
Show/Hide
|
C22H28N6OS
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0501478
|
1-(2,3-dichlorophenyl)-N-(2,3-dihydro-1-benzofuran-4-ylmethyl)tetrazol-5-amine
Show/Hide
|
C16H13Cl2N5O
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0504368
|
1-(2,3-dichlorophenyl)-N-(2,3-dihydro-1-benzofuran-3-yl)tetrazol-5-amine
Show/Hide
|
C15H11Cl2N5O
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0451498
|
US9409917, 73
Show/Hide
|
C16H12ClF3N2O2
|
1
|
| 1 |
IC50 = 20.2 nM
|
|
|
|
CP0470270
|
2-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]-1,2,4-triazol-3-amine
Show/Hide
|
C16H14Cl2N4
|
1
|
| 1 |
IC50 = 20.89 nM
|
|
|
|
CP0476759
|
1-(2,3-dichlorophenyl)-N-[(1R)-1-phenylethyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5
|
1
|
| 1 |
IC50 = 20.89 nM
|
|
|
|
CP0468294
|
[4-[[6-[4-[2-(1-adamantyl)acetyl]piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C36H39N5O6S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0502311
|
2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide
Show/Hide
|
C18H17ClF3N3O2
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
IC50 = 27 nM
|
|
|
|
CP0374105
|
N-[2-[4-(4-nitrophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C21H21N5O5S
|
1
|
| 1 |
IC50 = 21.1 nM
|
|
|
|
CP0529836
|
1-(2,3-dichlorophenyl)-N-[(3-fluorophenyl)methyl]tetrazol-5-amine
Show/Hide
|
C14H10Cl2FN5
|
1
|
| 1 |
IC50 = 21.88 nM
|
|
|
|
CP0377019
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-methylpyrazin-2-yl)benzamide
Show/Hide
|
C20H24ClN3O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0219388
|
CHEMBL4281588
Show/Hide
|
C16H10O3
|
1
|
| 1 |
IC50 = 22.4 nM
|
|
|
|
CP0398041
|
[4-[[3-[1-(adamantane-1-carbonyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H38N4O6S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0441354
|
1-(2,3-dichlorophenyl)-N-[[2-(dimethylamino)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C16H16Cl2N6
|
1
|
| 1 |
IC50 = 23.99 nM
|
|
|
|
CP0504372
|
1-(2,3-dichlorophenyl)-N-[(2-methylsulfanylphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5S
|
1
|
| 1 |
IC50 = 23.99 nM
|
|
|
|
CP0528245
|
N-(4-tert-butylphenyl)-4-[3,4-dioxo-2-(quinolin-5-ylamino)cyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C28H29N5O3
|
1
|
| 1 |
IC50 = 23.99 nM
|
|
|
|
CP0549125
|
[4-[[2,4-dioxo-6-[4-(tricyclo[3.3.1.03,7]nonane-3-carbonyl)piperazin-1-yl]pyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C34H35N5O6S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0518781
|
US9409917, 32
Show/Hide
|
C16H14ClFN2O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0531961
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-(2-methoxyethoxy)quinoline-5-carboxamide
Show/Hide
|
C20H23ClF2N2O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0451114
|
[4-[3-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H28N4O6S2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0468747
|
[4-[3-[1-[4-(dimethylamino)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-(methylcarbamoyl)benzenesulfonate
Show/Hide
|
C31H33N5O5S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0526469
|
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-1,4,4-trimethyl-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C16H18ClF3N2O2
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 25.12 nM
|
|
|
|
CP0500017
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(2-morpholin-4-ylethyl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C19H24ClF3N4O3
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0533309
|
(4S)-N-[(2,3-dichlorophenyl)methyl]-3-methyl-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C12H13Cl2N3O2
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0465869
|
US9409917, 26
Show/Hide
|
C16H14Cl2N2O3
|
1
|
| 1 |
IC50 = 25.6 nM
|
|
|
|
CP0549407
|
US9409917, 54
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 = 25.8 nM
|
|
|
|
CP0483451
|
1-(2,3-dichlorophenyl)-N-(2-phenylpropan-2-yl)tetrazol-5-amine
Show/Hide
|
C16H15Cl2N5
|
1
|
| 1 |
IC50 = 26.92 nM
|
|
|
|
CP0474567
|
[4-[[6-[4-[4-chloro-3-(trifluoromethyl)benzoyl]piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H25ClF3N5O6S
|
2
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0561887
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C23H29ClF2N4O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0451117
|
[4-[[6-[4-(4-nitrobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26N6O8S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0459177
|
1-(2,3-dichlorophenyl)-N-[[2-[2-(diethylamino)ethoxy]phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C20H24Cl2N6O
|
1
|
| 1 |
IC50 = 27.54 nM
|
|
|
|
CP0397844
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-(6-methoxypyridazin-3-yl)benzamide
Show/Hide
|
C20H24ClN3O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0441357
|
1-(2,3-dichlorophenyl)-N-[(2-morpholin-4-ylphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C18H18Cl2N6O
|
1
|
| 1 |
IC50 = 28.18 nM
|
|
|
|
CP0467678
|
1-(2,3-dichlorophenyl)-N-[(2,3-dimethylphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C16H15Cl2N5
|
1
|
| 1 |
IC50 = 28.18 nM
|
|
|
|
CP0498949
|
1-(2,3-dichlorophenyl)-N-[(1S)-2,3-dihydro-1H-inden-1-yl]tetrazol-5-amine
Show/Hide
|
C16H13Cl2N5
|
1
|
| 1 |
IC50 = 29.51 nM
|
|
|
|
CP0398155
|
[4-[[3-[1-(3-bromoadamantane-1-carbonyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H37BrN4O6S
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0476783
|
1-(2,3-dichlorophenyl)-N-[(2,5-difluorophenyl)methyl]tetrazol-5-amine
Show/Hide
|
C14H9Cl2F2N5
|
1
|
| 1 |
IC50 = 30.2 nM
|
|
|
|
CP0389981
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-methylpyridin-2-yl)benzamide
Show/Hide
|
C21H25ClN2O2
|
2
|
| 1 |
IC50 = 31 nM
|
|
|
| 2 |
IC50 = 32 nM
|
|
|
|
CP0417327
|
[4-[[6-[4-(3-bromoadamantane-1-carbonyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H36BrN5O6S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0567477
|
2-(cyclopenten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Show/Hide
|
C11H19BO2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0475288
|
[2-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-3H-benzimidazol-5-yl] isoquinoline-5-sulfonate
Show/Hide
|
C29H22ClF3N4O4S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0305060
|
2-(4-chlorophenyl)-N-[1-[(Z)-[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]acetamide
Show/Hide
|
C21H25ClN6O
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0399824
|
N-[1-[(E)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(4-methylsulfanylphenyl)acetamide
Show/Hide
|
C23H29N5OS
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0417432
|
N-[1-[[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C28H28N6O
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0417433
|
N-[2,2-dichloro-1-[[(cyanoamino)-[(2-methoxypyridin-3-yl)amino]methylidene]amino]propyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C21H24Cl2N6O4
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0467315
|
N-[1-[(Z)-[(cyanoamino)-[(2,6-dimethoxypyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C24H32N6O5
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0385016
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(1-methylpiperidin-4-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C19H24ClF3N4O2
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0459178
|
1-(2,3-dichlorophenyl)-N-[[2-(difluoromethoxy)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C15H11Cl2F2N5O
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0501477
|
N-[(2-chlorophenyl)methyl]-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C14H10Cl3N5
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0397256
|
N-[(3-chloro-2-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3,5-dimethylimidazol-4-yl]acetamide
Show/Hide
|
C21H20ClF2N3O
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0489471
|
2-chloro-5-(5-fluoropyridin-2-yl)-N-((1-hydroxycycloheptyl)methyl)benzamide
Show/Hide
|
C20H22ClFN2O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0500639
|
2-chloro-5-(5-fluoropyrimidin-2-yl)-N-((1-hydroxycyclohexyl)methyl)benzamide
Show/Hide
|
C18H19ClFN3O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0468752
|
[4-[3-[1-[4-(dimethylamino)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-cyanobenzenesulfonate
Show/Hide
|
C30H29N5O4S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0447237
|
1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
Show/Hide
|
C19H17N5
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0439755
|
N-[2-(4-benzylpiperazin-1-yl)-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C22H24N4O3S
|
1
|
| 1 |
IC50 = 35.1 nM
|
|
|
|
CP0451550
|
US9409917, 115
Show/Hide
|
C16H14Cl2N2O3
|
1
|
| 1 |
IC50 = 35.4 nM
|
|
|
|
CP0451549
|
US9409917, 113
Show/Hide
|
C17H15BrN2O2
|
1
|
| 1 |
IC50 = 35.9 nM
|
|
|
|
CP0557987
|
6-chloro-2-(cyclopenten-1-yl)-N-[(4,4-difluorocyclohexyl)methyl]quinoline-5-carboxamide
Show/Hide
|
C22H23ClF2N2O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0531962
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-pyrrolidin-1-ylquinoline-5-carboxamide
Show/Hide
|
C21H24ClF2N3O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0577861
|
US9409917, 45
Show/Hide
|
C15H12Cl2N2O2
|
1
|
| 1 |
IC50 = 37.2 nM
|
|
|
|
CP0395186
|
1-(2,3-dichlorophenyl)-N-[(1S)-1-phenylethyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5
|
1
|
| 1 |
IC50 = 38.9 nM
|
|
|
|
CP0064246
|
A-740003
Show/Hide
|
C26H30N6O3
|
5
|
| 1 |
IC50 = 39.81 nM
|
|
|
| 2 |
IC50 = 81 nM
|
|
|
| 3 |
IC50 = 82 nM
|
|
|
| 4 |
IC50 = 86 nM
|
|
|
| 5 |
IC50 = 109 nM
|
|
|
|
CP0399814
|
N-[1-[(E)-[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(4-cyanophenyl)acetamide
Show/Hide
|
C25H25N7O
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0501529
|
1-(2,3-dichlorophenyl)-N-[(4-fluorophenyl)methyl]tetrazol-5-amine
Show/Hide
|
C14H10Cl2FN5
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0127922
|
N-[(2-chloro-4-fluorophenyl)methyl]-2-(3,5-dimethyl-2-phenylimidazol-4-yl)acetamide
Show/Hide
|
C20H19ClFN3O
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0493954
|
N-[(3-chloro-2-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]acetamide
Show/Hide
|
C22H22ClF2N3O
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0495326
|
N-[(2-chloro-4-fluorophenyl)methyl]-2-[2-(2,4-difluorophenyl)-3,5-dimethylimidazol-4-yl]acetamide
Show/Hide
|
C20H17ClF3N3O
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0326577
|
(S)-tert-butyl 4-(3-(4-(isoquinolin-5-ylsulfonyloxy)phenyl)-2-(isoquinoline-5-sulfonamido)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C36H37N5O8S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0511193
|
N-[2-oxo-2-[4-(2-phenylethyl)piperazin-1-yl]ethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C23H26N4O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0489470
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(pyridin-2-yl)benzamide
Show/Hide
|
C20H23ClN2O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0379077
|
N-[2-[4-(4-acetylphenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C23H24N4O4S
|
1
|
| 1 |
IC50 = 40.2 nM
|
|
|
|
CP0459176
|
1-(2,3-dichlorophenyl)-N-[(3-methoxyphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C15H13Cl2N5O
|
1
|
| 1 |
IC50 = 40.74 nM
|
|
|
|
CP0451120
|
[2-[1-[4-(dimethylamino)benzoyl]piperidin-4-yl]-3H-benzimidazol-5-yl] isoquinoline-5-sulfonate
Show/Hide
|
C30H29N5O4S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0492894
|
US9409917, 55
Show/Hide
|
C16H11ClF4N2O2
|
1
|
| 1 |
IC50 = 41.6 nM
|
|
|
|
CP0455717
|
[4-[[6-[4-(4-methylsulfonylbenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H29N5O8S2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0468741
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H24ClF3N4O4S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0468746
|
[4-[3-[1-(4-nitrobenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-cyanobenzenesulfonate
Show/Hide
|
C28H23N5O6S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0473076
|
2-chloro-N-((4,4-difluoro-1-hydroxycycloheptyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide
Show/Hide
|
C19H19ClF3N3O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0545005
|
US9409917, 62
Show/Hide
|
C20H20F5N5O2
|
1
|
| 1 |
IC50 = 46.9 nM
|
|
|
|
CP0568242
|
US9409917, 42
Show/Hide
|
C16H15ClN2O2
|
1
|
| 1 |
IC50 = 46.9 nM
|
|
|
|
CP0574305
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-[3-(2-hydroxyethyl)pyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C23H28ClF2N3O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0561888
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]quinoline-5-carboxamide
Show/Hide
|
C23H29ClF2N4O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0399818
|
N-[1-[(Z)-[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-4-(4-methoxyphenyl)butanamide
Show/Hide
|
C24H32N6O2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0417435
|
4-chloro-N-[2,2-dichloro-1-[[(cyanoamino)-[(2,6-dimethoxypyridin-3-yl)amino]methylidene]amino]propyl]benzamide
Show/Hide
|
C19H19Cl3N6O3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0467309
|
2-(1,3-benzodioxol-5-yl)-N-[1-[[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]acetamide
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0510504
|
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(2-methoxypyridin-3-yl)amino]methylidene]amino]propyl]-3,5-dimethoxybenzamide
Show/Hide
|
C20H22Cl2N6O4
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0378257
|
N-[(2-chloro-6-methylphenyl)methyl]-2-(3,5-dimethyl-2-phenylimidazol-4-yl)acetamide
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0504872
|
N-[(2-chloro-6-methylphenyl)methyl]-2-(3-ethyl-5-methyl-2-phenylimidazol-4-yl)acetamide
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0505144
|
N-[(3-chloro-2-methylphenyl)methyl]-2-(3-ethyl-5-methyl-2-phenylimidazol-4-yl)acetamide
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0513227
|
N-[(2-chloro-6-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]acetamide
Show/Hide
|
C22H22ClF2N3O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0524760
|
N-[(3-chloro-2-methylphenyl)methyl]-2-(3,5-dimethyl-2-phenylimidazol-4-yl)acetamide
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0377021
|
2-chloro-N-((3,3-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide
Show/Hide
|
C18H17ClF3N3O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0552798
|
[4-[[4-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-2,5-dioxopyrrolidin-3-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H27ClF3N3O6S
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0492893
|
US9409917, 50
Show/Hide
|
C17H16Cl2N2O4
|
1
|
| 1 |
IC50 = 54.6 nM
|
|
|
|
CP0441355
|
1-(2,3-dichlorophenyl)-N-[(2-ethoxyphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C16H15Cl2N5O
|
1
|
| 1 |
IC50 = 54.95 nM
|
|
|
|
CP0494356
|
1-(2,3-dichlorophenyl)-N-[(2,3-difluorophenyl)methyl]tetrazol-5-amine
Show/Hide
|
C14H9Cl2F2N5
|
1
|
| 1 |
IC50 = 54.95 nM
|
|
|
|
CP0482438
|
[4-[3-[1-(4-propan-2-ylbenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H32N4O4S
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0528338
|
2-chloro-5-(5-chloropyridin-2-yl)-N-((1-hydroxycycloheptyl)methyl)benzamide
Show/Hide
|
C20H22Cl2N2O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0407519
|
3-[[5-[2-chloro-3-(trifluoromethyl)phenyl]tetrazol-1-yl]methyl]pyridine
Show/Hide
|
C14H9ClF3N5
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0419659
|
US9409917, 5
Show/Hide
|
C15H12Cl2N2O2
|
1
|
| 1 |
IC50 = 59.2 nM
|
|
|
|
CP0433498
|
N-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C21H21FN4O3S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0385942
|
[4-[[6-[4-(4-chlorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26ClN5O6S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0396502
|
ethyl 5-(adamantane-1-carbonylamino)-1-[(4-methoxyphenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C31H34N2O5
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0478503
|
[4-[3-[1-(4-nitrobenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-(methylcarbamoyl)benzenesulfonate
Show/Hide
|
C29H27N5O7S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0305061
|
N-[1-[(Z)-[(cyanoamino)-(2,5-dimethylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C25H33N5O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0399812
|
N-[1-[[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-5-phenylpentanamide
Show/Hide
|
C24H32N6O
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0435265
|
4-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(2-methoxypyridin-3-yl)amino]methylidene]amino]propyl]benzamide
Show/Hide
|
C18H17Cl3N6O2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0467305
|
N-[1-[[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-2-(3-fluoro-4-methylphenyl)acetamide
Show/Hide
|
C22H27FN6O
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0473675
|
4-chloro-N-[2,2-dichloro-1-[[[(2-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
Show/Hide
|
C17H14Cl4N6O
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0475892
|
N-[1-[[(2-chloroanilino)-(cyanoamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H28ClN5O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0476197
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(4-methoxyphenyl)acetamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0523251
|
2-(4-chlorophenyl)-N-[1-[[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]acetamide
Show/Hide
|
C22H26ClN5O
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0378258
|
2-[2-(2,4-difluorophenyl)-3,5-dimethylimidazol-4-yl]-N-[(2,3,4-trifluorophenyl)methyl]acetamide
Show/Hide
|
C20H16F5N3O
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0397258
|
N-[(3-chloro-2-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-methylimidazol-4-yl]acetamide
Show/Hide
|
C20H18ClF2N3O
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0487248
|
[4-[[6-[4-(3,4-dichlorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H25Cl2N5O6S
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0549994
|
N-(3,4-dimethoxyphenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]-2-phenylpiperazine-1-carboxamide
Show/Hide
|
C30H30N4O5
|
1
|
| 1 |
IC50 = 64.57 nM
|
|
|
|
CP0417328
|
[4-[[6-[4-(cyclohexanecarbonyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H33N5O6S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0507307
|
US9409917, 15
Show/Hide
|
C15H11Cl2FN2O2
|
1
|
| 1 |
IC50 = 66.8 nM
|
|
|
|
CP0545002
|
US9409917, 38
Show/Hide
|
C17H16Cl2N2O2
|
1
|
| 1 |
IC50 = 67.1 nM
|
|
|
|
CP0539963
|
US9409917, 20
Show/Hide
|
C15H11Cl2FN2O2
|
1
|
| 1 |
IC50 = 67.9 nM
|
|
|
|
CP0556281
|
[4-[[2,5-dioxo-3-[1-(tricyclo[3.3.1.03,7]nonane-3-carbonyl)piperidin-4-yl]imidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C34H36N4O6S
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0093745
|
[4-[[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H26ClF3N4O6S
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0504356
|
N-[(5-chloro-2-fluorophenyl)methyl]-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C14H9Cl3FN5
|
1
|
| 1 |
IC50 = 70.79 nM
|
|
|
|
CP0544916
|
US9409917, 9
Show/Hide
|
C17H16Cl2N2O3
|
1
|
| 1 |
IC50 = 70.8 nM
|
|
|
|
CP0219389
|
CHEMBL4292211
Show/Hide
|
C10H5IO3
|
1
|
| 1 |
IC50 = 71.2 nM
|
|
|
|
CP0425473
|
[4-[[6-[4-(4-bromobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26BrN5O6S
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0551898
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-(2-hydroxyethylamino)quinoline-5-carboxamide
Show/Hide
|
C19H22ClF2N3O2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0552679
|
N-(cycloheptylmethyl)-1-(2-hydroxyethyl)indole-3-carboxamide
Show/Hide
|
C19H26N2O2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0398148
|
[4-[[3-[1-(3,4-dichlorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26Cl2N4O6S
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0392898
|
2-(1-adamantyl)-N-[2-(4-nitrophenyl)quinolin-5-yl]acetamide
Show/Hide
|
C27H27N3O3
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0483531
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-cyanobenzenesulfonate
Show/Hide
|
C29H22ClF3N4O4S
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0483450
|
1-(2,3-dichlorophenyl)-N-[[2-(trifluoromethoxy)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C15H10Cl2F3N5O
|
1
|
| 1 |
IC50 = 74.13 nM
|
|
|
|
CP0501527
|
1-(2,3-dichlorophenyl)-N-[[2-(trifluoromethyl)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C15H10Cl2F3N5
|
1
|
| 1 |
IC50 = 74.13 nM
|
|
|
|
CP0579682
|
4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]-N-(4-nitrophenyl)piperazine-1-carboxamide
Show/Hide
|
C22H21N5O5
|
1
|
| 1 |
IC50 = 74.13 nM
|
|
|
|
CP0399445
|
N'-(3,5-dichloropyridin-4-yl)adamantane-2-carbohydrazide
Show/Hide
|
C16H19Cl2N3O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0475276
|
[4-[3-[1-(4-methoxybenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H28N4O5S
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0201601
|
3-(2,3-dichlorophenyl)-4-[(2-methylphenyl)methyl]-1,2,4-triazole
Show/Hide
|
C16H13Cl2N3
|
1
|
| 1 |
IC50 = 77.62 nM
|
|
|
|
CP0417434
|
N-[1-[(Z)-[[(2-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C22H27ClN6O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0445442
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-4-phenylbutanamide
Show/Hide
|
C24H31N5O
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0467313
|
N-[1-[(E)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-4-(4-methoxyphenyl)butanamide
Show/Hide
|
C25H33N5O2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0518430
|
N-[1-[[(5-chloro-2-fluoroanilino)-(cyanoamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27ClFN5O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0388208
|
(4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(6-methylpyridin-2-yl)-2-oxoimidazolidine-4-carboxamide
Show/Hide
|
C19H18ClF3N4O2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0414524
|
US9409917, 103
Show/Hide
|
C16H12ClF3N2O2
|
1
|
| 1 |
IC50 = 80.4 nM
|
|
|
|
CP0428809
|
US9409917, 92
Show/Hide
|
C20H21F3N4O3
|
1
|
| 1 |
IC50 = 82.2 nM
|
|
|
|
CP0381972
|
[4-[[3-[1-[2-(1-adamantyl)acetyl]piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C36H40N4O6S
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0531705
|
N-(2-adamantylmethyl)-5-[[(3S)-3-aminopyrrolidin-1-yl]methyl]-2-chlorobenzamide
Show/Hide
|
C23H32ClN3O
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0492891
|
US9409917, 43
Show/Hide
|
C15H12ClFN2O2
|
1
|
| 1 |
IC50 = 86.8 nM
|
|
|
|
CP0509275
|
N-[(2-chloro-3,6-difluorophenyl)methyl]-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C14H8Cl3F2N5
|
1
|
| 1 |
IC50 = 87.1 nM
|
|
|
|
CP0549297
|
N-(2-chlorophenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]-2-phenylpiperazine-1-carboxamide
Show/Hide
|
C28H25ClN4O3
|
1
|
| 1 |
IC50 = 87.1 nM
|
|
|
|
CP0534911
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-(cyclopropylcarbamoyl)benzenesulfonate
Show/Hide
|
C32H28ClF3N4O5S
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0455883
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]-2-(2-methoxyethylamino)quinoline-5-carboxamide
Show/Hide
|
C20H24ClF2N3O2
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0542885
|
N-[(2R)-2-(4-chlorophenyl)-2-morpholin-4-ylethyl]-2-pyrimidin-2-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C21H19ClF3N5O2S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0505542
|
N-[2-(4-naphthalen-1-ylpiperazin-1-yl)-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C25H24N4O3S
|
1
|
| 1 |
IC50 = 90.2 nM
|
|
|
|
CP0557986
|
6-chloro-2-cyclopentyl-N-[(4,4-difluorocyclohexyl)methyl]quinoline-5-carboxamide
Show/Hide
|
C22H25ClF2N2O
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0504734
|
[4-[[3-[1-(3,5-dimethyladamantane-1-carbonyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C37H42N4O6S
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0381737
|
[4-[[6-[4-(4-chloro-3-fluorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H25ClFN5O6S
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0467314
|
N-[1-[(Z)-[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-2-(4-fluorophenyl)acetamide
Show/Hide
|
C21H25FN6O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0467316
|
N-[1-[(Z)-[(cyanoamino)-(2,4,6-trifluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H26F3N5O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0495664
|
2-(3,4-dimethoxyphenyl)-N-[2,2,2-trichloro-1-[(2-methylphenyl)carbamothioylamino]ethyl]acetamide
Show/Hide
|
C20H22Cl3N3O3S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0510497
|
N-[1-[(Z)-[(cyanoamino)-[(2-methoxypyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H30N6O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0526152
|
N-[1-[(Z)-[(cyanoamino)-(2,5-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27F2N5O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0537880
|
N-[1-[(Z)-[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-4-pyridin-3-ylbutanamide
Show/Hide
|
C25H29N7O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0464557
|
N-[2-(4-benzylpiperazin-1-yl)-2-oxoethyl]-N-methylisoquinoline-5-sulfonamide
Show/Hide
|
C23H26N4O3S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0499829
|
2-(3,5-dimethyl-2-phenylimidazol-4-yl)-N-[(2,3,4-trifluorophenyl)methyl]acetamide
Show/Hide
|
C20H18F3N3O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0499830
|
N-[(2-chloro-4-fluorophenyl)methyl]-2-(3-ethyl-5-methyl-2-phenylimidazol-4-yl)acetamide
Show/Hide
|
C21H21ClFN3O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0504871
|
N-[(2-chloro-4-fluorophenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]acetamide
Show/Hide
|
C21H19ClF3N3O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0437634
|
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-5-oxo-1-thiophen-2-ylpyrrolidine-2-carboxamide
Show/Hide
|
C17H14ClF3N2O2S
|
3
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 217.8 nM
|
|
|
| 3 |
Ki = 44 nM
|
|
|
|
CP0528238
|
3-[4-(3,4-dimethoxybenzoyl)-3-phenylpiperazin-1-yl]-4-(2-methylanilino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C30H29N3O5
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 549.54 nM
|
|
|
|
CP0577911
|
methyl 4-[[4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carbonyl]amino]benzoate
Show/Hide
|
C24H24N4O5
|
1
|
| 1 |
IC50 = 102.33 nM
|
|
|
|
CP0487249
|
[4-[[6-[4-(2-cyclohexylacetyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H35N5O6S
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0068448
|
[1-(4-chlorophenyl)triazol-4-yl]methyl decanoate
Show/Hide
|
C19H26ClN3O2
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0379052
|
[4-[[3-[1-[2-(2-bicyclo[2.2.1]heptanyl)acetyl]piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H36N4O6S
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0455716
|
[4-[3-[1-[4-(2-hydroxypropan-2-yl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H32N4O5S
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0460704
|
1-(2,3-dichlorophenyl)-N-[(2-propan-2-yloxyphenyl)methyl]tetrazol-5-amine
Show/Hide
|
C17H17Cl2N5O
|
1
|
| 1 |
IC50 = 109.65 nM
|
|
|
|
CP0528234
|
N-(4-tert-butylphenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 109.65 nM
|
|
|
|
CP0016002
|
(1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl)-4phenylpiperazine)
Show/Hide
|
C38H35N5O6S2
|
6
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 158 nM
|
|
|
| 3 |
IC50 = 175 nM
|
|
|
| 4 |
IC50 = 250 nM
|
|
|
| 5 |
IC50 = 280 nM
|
|
|
| 6 |
IC50 = 340 nM
|
|
|
|
CP0451113
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-(methylcarbamoyl)benzenesulfonate
Show/Hide
|
C30H26ClF3N4O5S
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0351859
|
(S)-4-(3-(4-benzoylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)phenyl 4-nitrobenzenesulfonate
Show/Hide
|
C34H32N4O9S
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0411961
|
methyl 5-(adamantane-1-carbonylamino)-1-[(4-methoxyphenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C30H32N2O5
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0441356
|
N-[(3-chlorophenyl)methyl]-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C14H10Cl3N5
|
1
|
| 1 |
IC50 = 120.23 nM
|
|
|
|
CP0379798
|
US9409917, 78
Show/Hide
|
C22H22F5N3O2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0476965
|
2-(1-adamantyl)-N-[2-(4-chlorophenyl)quinolin-5-yl]acetamide
Show/Hide
|
C27H27ClN2O
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0078785
|
A-438079
Show/Hide
|
C13H9Cl2N5
|
3
|
| 1 |
IC50 = 123.03 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
| 3 |
IC50 = 2100 nM
|
|
|
|
CP0425472
|
[4-[[6-[4-[2-(2-bicyclo[2.2.1]heptanyl)acetyl]piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H35N5O6S
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0451497
|
US9409917, 56
Show/Hide
|
C16H12ClN3O2
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0493955
|
2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]-N-[(2,3,4-trifluorophenyl)methyl]acetamide
Show/Hide
|
C21H18F5N3O
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0517256
|
US9409917, 8
Show/Hide
|
C17H24N2O3
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0427197
|
N-[2-[4-(4-methylphenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C22H24N4O3S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0475818
|
3-cyclohexyl-N'-(3,5-dichloropyridin-4-yl)propanehydrazide
Show/Hide
|
C14H19Cl2N3O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0385943
|
[4-[[6-[4-(bicyclo[2.2.1]heptane-2-carbonyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H33N5O6S
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0398149
|
[4-[[3-[1-(4-chlorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H27ClN4O6S
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0556733
|
[4-[[3-[1-(cyclohexanecarbonyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H34N4O6S
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0514137
|
2-chloro-5-(5-cyanopyridin-2-yl)-N-((1-hydroxycycloheptyl)methyl)benzamide
Show/Hide
|
C21H22ClN3O2
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0528231
|
N-(4-chlorophenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]-2-phenylpiperazine-1-carboxamide
Show/Hide
|
C28H25ClN4O3
|
1
|
| 1 |
IC50 = 134.9 nM
|
|
|
|
CP0468745
|
[4-[3-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-cyanobenzenesulfonate
Show/Hide
|
C29H26N4O6S2
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0549248
|
[4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl] isoquinoline-8-sulfonate
Show/Hide
|
C38H35N5O6S2
|
1
|
| 1 |
IC50 = 149 nM
|
|
|
|
CP0579718
|
4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]-N-phenylpiperazine-1-carboxamide
Show/Hide
|
C22H22N4O3
|
1
|
| 1 |
IC50 = 151.36 nM
|
|
|
|
CP0567826
|
[4-[3-[1-(4-nitrobenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-(cyclopropylcarbamoyl)benzenesulfonate
Show/Hide
|
C31H29N5O7S
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0576367
|
[4-[3-[1-[3-(dimethylamino)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H31N5O4S
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
|
CP0539964
|
US9409917, 49
Show/Hide
|
C16H14Cl2N2O2
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0455051
|
2-(1-adamantyl)-N-(1H-indazol-5-yl)acetamide
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0467310
|
N-[1-[(Z)-[(cyanoamino)-(2-methoxyanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C24H31N5O4
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0397257
|
2-(3-ethyl-5-methyl-2-phenylimidazol-4-yl)-N-[(2,3,4-trifluorophenyl)methyl]acetamide
Show/Hide
|
C21H20F3N3O
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0552761
|
N-(4-chlorophenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C22H21ClN4O3
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0482439
|
[4-[3-[1-(4-methoxybenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-(methylcarbamoyl)benzenesulfonate
Show/Hide
|
C30H30N4O6S
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0429806
|
[4-[[6-[4-(4-chloro-2-fluorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H25ClFN5O6S
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0551599
|
[4-[[6-[4-(3,4-difluorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H25F2N5O6S
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
|
CP0917988
|
9-(4,5-Dimethoxy-2-nitro-benzyloxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C31H33IN2O8
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0381123
|
(R)-(4-(4-hydroxy-3-methylbenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C33H33N5O4
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0426121
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-(6-oxo-1H-pyridazin-3-yl)benzamide
Show/Hide
|
C19H22ClN3O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0557495
|
[4-[3-[1-(4-phenoxybenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C36H30N4O5S
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0478935
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-1-(furan-3-yl)-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C16H14Cl2N2O3
|
3
|
| 1 |
IC50 = 199.5 nM
|
|
|
| 2 |
IC50 = 422.1 nM
|
|
|
| 3 |
Ki = 86 nM
|
|
|
|
CP0467307
|
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]propyl]-3,5-dimethoxybenzamide
Show/Hide
|
C20H22Cl2N6O3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0467308
|
N-[1-[(Z)-[(cyanoamino)-(2-fluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H28FN5O3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0467317
|
N-[1-[(Z)-[(cyanoamino)-(2,6-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27F2N5O3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0509085
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-3-(3,4-dimethoxyphenyl)propanamide
Show/Hide
|
C25H33N5O3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0504868
|
N-[(2-chloro-4-fluorophenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-methylimidazol-4-yl]acetamide
Show/Hide
|
C19H15ClF3N3O
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0399446
|
2-cycloheptyl-N'-(3,5-dichloropyridin-4-yl)acetohydrazide
Show/Hide
|
C14H19Cl2N3O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0549247
|
[4-[3-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-(methylcarbamoyl)benzenesulfonate
Show/Hide
|
C30H30N4O7S2
|
1
|
| 1 |
IC50 = 202 nM
|
|
|
|
CP0568766
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-(diethylcarbamoyl)benzenesulfonate
Show/Hide
|
C33H32ClF3N4O5S
|
1
|
| 1 |
IC50 = 202 nM
|
|
|
|
CP0446966
|
2-(2-bicyclo[2.2.1]heptanyl)-N'-(3,5-dichloropyridin-4-yl)acetohydrazide
Show/Hide
|
C14H17Cl2N3O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0390512
|
2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-methoxypyridin-2-yl)benzamide
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0474568
|
[4-[[6-[4-(3-chlorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26ClN5O6S
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0577863
|
US9409917, 91
Show/Hide
|
C21H25N5O3
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0400694
|
[4-[[3-[1-(3,4-difluorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26F2N4O6S
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0490341
|
(S)-4-(3-(4-benzoylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)-2,6-dimethylphenyl benzenesulfonate
Show/Hide
|
C36H37N3O7S
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0512563
|
[4-[[3-[1-(3-chlorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H27ClN4O6S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0573113
|
3-[4-(3,4-dimethoxybenzoyl)-3-phenylpiperazin-1-yl]-4-(quinolin-5-ylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C32H28N4O5
|
1
|
| 1 |
IC50 = 223.87 nM
|
|
|
|
CP0420328
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-thiophen-2-ylpyrrolidine-2-carboxamide
Show/Hide
|
C16H14Cl2N2O2S
|
3
|
| 1 |
IC50 = 229 nM
|
|
|
| 2 |
IC50 = 720 nM
|
|
|
| 3 |
Ki = 147 nM
|
|
|
|
CP0455884
|
6-chloro-N-[(4,4-difluorocyclohexyl)methyl]quinoline-5-carboxamide
Show/Hide
|
C17H17ClF2N2O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0429978
|
2-chloro-5-(6-cyanopyridin-2-yl)-N-((1-hydroxycycloheptyl)methyl)benzamide
Show/Hide
|
C21H22ClN3O2
|
1
|
| 1 |
IC50 = 232 nM
|
|
|
|
CP0395185
|
1-(2,3-dichlorophenyl)-N-[[3-(trifluoromethyl)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C15H10Cl2F3N5
|
1
|
| 1 |
IC50 = 234.42 nM
|
|
|
|
CP0478505
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] thiophene-2-sulfonate
Show/Hide
|
C26H21ClF3N3O4S2
|
1
|
| 1 |
IC50 = 238 nM
|
|
|
|
CP0557500
|
[4-[3-[1-(4-methoxybenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-(cyclopropylcarbamoyl)benzenesulfonate
Show/Hide
|
C32H32N4O6S
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0491000
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-1-(furan-2-yl)-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C16H14Cl2N2O3
|
3
|
| 1 |
IC50 = 244 nM
|
|
|
| 2 |
IC50 = 575 nM
|
|
|
| 3 |
Ki = 118 nM
|
|
|
|
CP0549246
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-nitrobenzenesulfonate
Show/Hide
|
C28H22ClF3N4O6S
|
1
|
| 1 |
IC50 = 249 nM
|
|
|
|
CP0381124
|
(R)-(4-(4-chlorobenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C32H30ClN5O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0445441
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,5-dimethoxyphenyl)acetamide
Show/Hide
|
C24H31N5O3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0445444
|
N-[1-[(Z)-[(cyanoamino)-(2,4-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27F2N5O3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0473673
|
N-[1-[(Z)-[(cyanoamino)-[(2-methylpyridin-3-yl)amino]methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H30N6O3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0495665
|
N-[1-[(Z)-[(cyanoamino)-(isoquinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C26H30N6O3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0385418
|
[4-[[6-[4-(3,5-dimethyladamantane-1-carbonyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C37H41N5O6S
|
1
|
| 1 |
IC50 = 252 nM
|
|
|
|
CP0549399
|
US9409917, 33
Show/Hide
|
C22H20N2O3
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0528023
|
4-((S)-3-((R)-4-benzoyl-3-methylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C36H37N3O7S
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
|
CP0437637
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(1,3-thiazol-4-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C15H13Cl2N3O2S
|
3
|
| 1 |
IC50 = 256.4 nM
|
|
|
| 2 |
IC50 = 383.7 nM
|
|
|
| 3 |
Ki = 78 nM
|
|
|
|
CP0377846
|
N-[(4-chlorophenyl)methyl]-1-(2,3-dichlorophenyl)tetrazol-5-amine
Show/Hide
|
C14H10Cl3N5
|
1
|
| 1 |
IC50 = 257.04 nM
|
|
|
|
CP0531692
|
[4-[3-[1-(3,4-dimethoxybenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H30N4O6S
|
1
|
| 1 |
IC50 = 259 nM
|
|
|
|
CP0513774
|
4-((S)-3-((S)-4-benzoyl-3-methylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C36H37N3O7S
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0949630
|
13-(3,5-Dimethoxy-benzyl)-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride
Show/Hide
|
C29H28ClNO6
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0392862
|
propyl 5-(adamantane-1-carbonylamino)-1-[(4-methoxyphenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C32H36N2O5
|
1
|
| 1 |
IC50 = 263 nM
|
|
|
|
CP0494551
|
2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-(2-methylpyrazol-3-yl)benzamide
Show/Hide
|
C19H24ClN3O2
|
1
|
| 1 |
IC50 = 266 nM
|
|
|
|
CP0468744
|
[4-[3-[1-(4-cyanobenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H25N5O4S
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0414519
|
US9409917, 52
Show/Hide
|
C18H26N2O3
|
1
|
| 1 |
IC50 = 276 nM
|
|
|
|
CP0528232
|
N-(3,4-dimethoxyphenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C24H26N4O5
|
1
|
| 1 |
IC50 = 302 nM
|
|
|
|
CP0546868
|
US9409917, 118
Show/Hide
|
C16H15ClN2O3
|
1
|
| 1 |
IC50 = 304 nM
|
|
|
|
CP0580013
|
4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]-N-(4-methylphenyl)piperazine-1-carboxamide
Show/Hide
|
C23H24N4O3
|
1
|
| 1 |
IC50 = 309.03 nM
|
|
|
|
CP0443580
|
(R)-(4-benzyl-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C32H31N5O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0566853
|
[4-[3-[1-(4-methoxybenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-cyanobenzenesulfonate
Show/Hide
|
C29H26N4O5S
|
1
|
| 1 |
IC50 = 312 nM
|
|
|
|
CP0399823
|
N-[1-[(Z)-[(cyanoamino)-(2,3-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27F2N5O3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0443427
|
N-[1-[(Z)-[(cyanoamino)-(4-fluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H28FN5O3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0501713
|
(S)-4-(2-(benzyloxycarbonyl)-3-(4-(4-fluorobenzoyl)piperazin-1-yl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C35H34FN3O7S
|
1
|
| 1 |
IC50 = 319 nM
|
|
|
|
CP0425986
|
N'-(3,5-dichloropyridin-4-yl)bicyclo[4.2.0]octa-1,3,5-triene-7-carbohydrazide
Show/Hide
|
C14H11Cl2N3O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0428804
|
US9409917, 36
Show/Hide
|
C17H15F3N2O2
|
1
|
| 1 |
IC50 = 334 nM
|
|
|
|
CP0420955
|
2-(2-adamantyl)-N'-(3,5-dichloropyridin-4-yl)acetohydrazide
Show/Hide
|
C17H21Cl2N3O
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0568247
|
US9409917, 106
Show/Hide
|
C17H16Cl2N2O2
|
1
|
| 1 |
IC50 = 346 nM
|
|
|
|
CP0877311
|
13-Ethyl-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium iodide
Show/Hide
|
C22H22INO4
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0379050
|
tert-butyl 4-[5-[(4-isoquinolin-5-ylsulfonyloxyphenyl)methyl]-2,4-dioxoimidazolidin-1-yl]piperidine-1-carboxylate
Show/Hide
|
C29H32N4O7S
|
1
|
| 1 |
IC50 = 355 nM
|
|
|
|
CP0416310
|
4-cyclohexyl-N'-(3,5-dichloropyridin-4-yl)butanehydrazide
Show/Hide
|
C15H21Cl2N3O
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0391778
|
[4-[[6-[4-(5-bromo-2-chlorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H25BrClN5O6S
|
1
|
| 1 |
IC50 = 361 nM
|
|
|
|
CP0437810
|
benzyl N-[(3,5-dichloropyridin-4-yl)amino]carbamate
Show/Hide
|
C13H11Cl2N3O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0537113
|
3-cyclopentyl-N'-(3,5-dichloropyridin-4-yl)propanehydrazide
Show/Hide
|
C13H17Cl2N3O
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0528233
|
N-(4-aminophenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C22H23N5O3
|
1
|
| 1 |
IC50 = 380.19 nM
|
|
|
|
CP0412034
|
N-(2-chloroquinolin-5-yl)-2-cyclohexylacetamide
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
IC50 = 385 nM
|
|
|
|
CP0545004
|
US9409917, 61
Show/Hide
|
C16H12ClN3O2
|
1
|
| 1 |
IC50 = 389 nM
|
|
|
|
CP0473674
|
N-[1-[(Z)-[(cyanoamino)-(3,5-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27F2N5O3
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0498495
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-3-(4-methoxyphenyl)propanamide
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0870393
|
13-(2-Chloro-6-fluoro-benzyl)-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride
Show/Hide
|
C27H22Cl2FNO4
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0568245
|
US9409917, 69
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0538127
|
[4-[3-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]imidazol-4-yl]phenyl] 3-(cyclopropylcarbamoyl)benzenesulfonate
Show/Hide
|
C32H32N4O7S2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0103280
|
CHEMBL4291798
Show/Hide
|
C10H5BrO3
|
1
|
| 1 |
IC50 = 414 nM
|
|
|
|
CP0414747
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(1,3-thiazol-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C15H13Cl2N3O2S
|
3
|
| 1 |
IC50 = 415 nM
|
|
|
| 2 |
IC50 = 2385 nM
|
|
|
| 3 |
Ki = 489 nM
|
|
|
|
CP0914998
|
13-(1-Iodo-butyl)-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride
Show/Hide
|
C24H25ClINO4
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0926172
|
13-Ethyl-2,3,10-trimethoxy-9-(2-methoxy-5-nitro-benzyloxy)-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C30H31IN2O7
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0472345
|
[4-[[3-[1-(4-chloro-2-fluorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26ClFN4O6S
|
1
|
| 1 |
IC50 = 423 nM
|
|
|
|
CP0568806
|
[1-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]indol-5-yl] isoquinoline-5-sulfonate
Show/Hide
|
C30H23ClF3N3O4S
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0501528
|
1-(2,3-dichlorophenyl)-N-[[4-(trifluoromethyl)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C15H10Cl2F3N5
|
1
|
| 1 |
IC50 = 436.52 nM
|
|
|
|
CP0933638
|
13-Allyl-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium iodide
Show/Hide
|
C23H22INO4
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0426451
|
2-(1-adamantyl)-N-(2-phenylquinolin-5-yl)acetamide
Show/Hide
|
C27H28N2O
|
1
|
| 1 |
IC50 = 447 nM
|
|
|
|
CP0489472
|
2-chloro-5-(5-fluoropyrimidin-2-yl)-N-((1-hydroxycyclopentyl)methyl)benzamide
Show/Hide
|
C17H17ClFN3O2
|
1
|
| 1 |
IC50 = 449 nM
|
|
|
|
CP0206094
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-1-methyl-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C13H14Cl2N2O2
|
3
|
| 1 |
IC50 = 474 nM
|
|
|
| 2 |
IC50 = 861.8 nM
|
|
|
| 3 |
Ki = 176 nM
|
|
|
|
CP0451495
|
US9409917, 35
Show/Hide
|
C16H15ClN2O2
|
1
|
| 1 |
IC50 = 475 nM
|
|
|
|
CP0114810
|
1-phenyltriazole-4-carbaldehyde
Show/Hide
|
C9H7N3O
|
1
|
| 1 |
IC50 = 478 nM
|
|
|
|
CP0525929
|
(S)-4-(2-(benzyloxycarbonyl)-3-(4-(4-bromobenzoyl)piperazin-1-yl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C35H34BrN3O7S
|
1
|
| 1 |
IC50 = 481 nM
|
|
|
|
CP0573112
|
1-N,4-N-bis(2-chlorophenyl)-2-phenylpiperazine-1,4-dicarboxamide
Show/Hide
|
C24H22Cl2N4O2
|
1
|
| 1 |
IC50 = 489.78 nM
|
|
|
|
CP0949631
|
2,3,9,10-Tetramethoxy-13-propyl-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C24H28INO4
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0503102
|
N-[(2-chloro-4-fluorophenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-ethylimidazol-4-yl]acetamide
Show/Hide
|
C20H17ClF3N3O
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0501715
|
4-((S)-3-((S)-4-benzoyl-2-methylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C36H37N3O7S
|
1
|
| 1 |
IC50 = 504 nM
|
|
|
|
CP0501712
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(4-bromophenylsulfonyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C32H36BrN3O8S
|
1
|
| 1 |
IC50 = 517 nM
|
|
|
|
CP0381120
|
(R)-(4-(4-methylbenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C33H33N5O3
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0074286
|
(2-phenyltriazol-4-yl)methanol
Show/Hide
|
C9H9N3O
|
1
|
| 1 |
IC50 = 522 nM
|
|
|
|
CP0665886
|
sodium 3-(((4-((E)-(4-(4-ethoxyphenylamino)phenyl)((E)-4-(ethyl(3-sulfonatobenzyl)iminio)-2-methylcyclohexa-2,5-dienylidene)methyl)-3-methylphenyl)(ethyl)amino)methyl)benzenesulfonate
Show/Hide
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C47H48N3NaO7S2
|
2
|
| 1 |
IC50 = 536 nM
|
|
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| 2 |
IC50 = 552 nM
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CP0522305
|
4-((S)-2-(benzyloxycarbonyl)-3-((S)-4-(4-(dimethylamino)benzoyl)-3-methylpiperazin-1-yl)-3-oxopropyl)phenyl 4-cyanobenzenesulfonate
Show/Hide
|
C38H39N5O7S
|
1
|
| 1 |
IC50 = 539 nM
|
|
|
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CP0472354
|
[4-[[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-1-methyl-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H28ClF3N4O6S
|
1
|
| 1 |
IC50 = 542 nM
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|
|
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CP0522992
|
(13R,13aS)-13-Ethyl-9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline
Show/Hide
|
C22H25NO4
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
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CP0513987
|
1-(2,3-dichlorophenyl)-N-[[3-(trifluoromethoxy)phenyl]methyl]tetrazol-5-amine
Show/Hide
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C15H10Cl2F3N5O
|
1
|
| 1 |
IC50 = 562.34 nM
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|
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CP0557494
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-aminobenzenesulfonate
Show/Hide
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C28H24ClF3N4O4S
|
1
|
| 1 |
IC50 = 565 nM
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|
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CP0510343
|
[4-[[3-(1-benzoylpiperidin-4-yl)-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
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C31H28N4O6S
|
1
|
| 1 |
IC50 = 574 nM
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|
|
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CP0385057
|
[4-[[6-[4-(2-chlorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26ClN5O6S
|
1
|
| 1 |
IC50 = 583 nM
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|
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CP0525931
|
(S)-4-(3-(4-benzoylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
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C35H35N3O7S
|
1
|
| 1 |
IC50 = 599 nM
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|
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CP0524672
|
2-(4-chlorophenyl)-N'-(3,5-dichloropyridin-4-yl)acetohydrazide
Show/Hide
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C13H10Cl3N3O
|
1
|
| 1 |
IC50 = 620 nM
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|
|
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CP0069500
|
4-(butoxymethyl)-1-(2,5-dichlorophenyl)triazole
Show/Hide
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C13H15Cl2N3O
|
1
|
| 1 |
IC50 = 621 nM
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CP0473672
|
N-[1-[[N'-[(2-chlorophenyl)methyl]-N-cyanocarbamimidoyl]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
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C24H30ClN5O3
|
1
|
| 1 |
IC50 = 630.96 nM
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|
|
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CP0399447
|
N'-(3,5-dichloropyridin-4-yl)-3-phenylpropanehydrazide
Show/Hide
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C14H13Cl2N3O
|
1
|
| 1 |
IC50 = 650 nM
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|
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CP0429803
|
[4-[[6-(4-benzoylpiperazin-1-yl)-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H27N5O6S
|
1
|
| 1 |
IC50 = 664 nM
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|
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CP0400675
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[4-[[3-[1-(2-chlorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H27ClN4O6S
|
1
|
| 1 |
IC50 = 666 nM
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|
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CP0568764
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] benzenesulfonate
Show/Hide
|
C28H23ClF3N3O4S
|
1
|
| 1 |
IC50 = 702 nM
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CP0375707
|
[4-[[6-[4-(4-fluorobenzoyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26FN5O6S
|
1
|
| 1 |
IC50 = 710 nM
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|
|
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CP0412027
|
methyl 5-(adamantane-1-carbonylamino)-1-[(4-chlorophenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C29H29ClN2O4
|
1
|
| 1 |
IC50 = 723 nM
|
|
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CP0525930
|
(S)-4-(2-(benzyloxycarbonyl)-3-oxo-3-(4-(4-(trifluoromethyl)benzoyl)piperazin-1-yl)propyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C36H34F3N3O7S
|
1
|
| 1 |
IC50 = 724 nM
|
|
|
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CP0560196
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(4-(trifluoromethoxy)phenylsulfonyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C33H36F3N3O9S
|
1
|
| 1 |
IC50 = 725 nM
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|
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CP0877312
|
13-Ethyl-2,3,10-trimethoxy-9-(5-methyl-2-nitro-benzyloxy)-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C30H31IN2O6
|
1
|
| 1 |
IC50 = 730 nM
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|
|
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CP0437809
|
2-cyclohexyl-N'-(3,5-dichloropyridin-4-yl)acetohydrazide
Show/Hide
|
C13H17Cl2N3O
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
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CP0469998
|
(R)-(4-(4-hydroxy-3-methylbenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl isoquinoline-5-carboxylate
Show/Hide
|
C33H31N5O4
|
1
|
| 1 |
IC50 = 740 nM
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CP0528235
|
N-cyclohexyl-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C22H28N4O3
|
1
|
| 1 |
IC50 = 741.31 nM
|
|
|
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CP0428805
|
US9409917, 37
Show/Hide
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C17H17ClN2O2
|
1
|
| 1 |
IC50 = 758 nM
|
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|
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CP0549298
|
N-(4-fluorophenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
Show/Hide
|
C22H21FN4O3
|
1
|
| 1 |
IC50 = 758.58 nM
|
|
|
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CP0498300
|
N'-(3,5-dichloropyridin-4-yl)-4-phenylbutanehydrazide
Show/Hide
|
C15H15Cl2N3O
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
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CP0510779
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(4-cyanophenylsulfonyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C33H36N4O8S
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
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CP0398069
|
[4-[[3-[(1-benzoylpiperidin-4-yl)methyl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H30N4O6S
|
1
|
| 1 |
IC50 = 789 nM
|
|
|
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CP0397171
|
(R)-(8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl isoquinoline-5-carboxylate
Show/Hide
|
C25H23N5O3
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
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CP0445445
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]hexanamide
Show/Hide
|
C20H31N5O
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
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CP0526151
|
N-[1-[(Z)-[(cyanoamino)-(3,4-difluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H27F2N5O3
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0518457
|
US9409917, 46
Show/Hide
|
C15H13ClN2O2
|
1
|
| 1 |
IC50 = 795 nM
|
|
|
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CP0433504
|
N-[3-oxo-3-(4-phenylpiperazin-1-yl)propyl]isoquinoline-5-sulfonamide
Show/Hide
|
C22H24N4O3S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
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CP0389854
|
methyl 5-(adamantane-1-carbonylamino)-1-[(4-nitrophenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C29H29N3O6
|
1
|
| 1 |
IC50 = 809 nM
|
|
|
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CP0426450
|
methyl 5-(adamantane-1-carbonylamino)-1-[(4-bromophenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C29H29BrN2O4
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
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CP0482168
|
methyl 5-(cyclohexanecarbonylamino)-1-[(4-methoxyphenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C26H28N2O5
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
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CP0478936
|
(2S)-N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-thiophen-3-ylpyrrolidine-2-carboxamide
Show/Hide
|
C16H14Cl2N2O2S
|
3
|
| 1 |
IC50 = 813.2 nM
|
|
|
| 2 |
IC50 = 1251.2 nM
|
|
|
| 3 |
Ki = 256 nM
|
|
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CP0932771
|
13-Ethyl-9-(4-fluoro-2-trifluoromethyl-benzyloxy)-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C30H28F4INO4
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0512561
|
[4-[[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-1-ethyl-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C34H30ClF3N4O6S
|
1
|
| 1 |
IC50 = 847 nM
|
|
|
|
CP0473498
|
(R)-(4-(4-bromobenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C32H30BrN5O3
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0528022
|
(R)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(tosyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C33H39N3O8S
|
1
|
| 1 |
IC50 = 861 nM
|
|
|
|
CP0457824
|
methyl 5-[[2-(1-adamantyl)acetyl]amino]-1-[(4-methoxyphenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C31H34N2O5
|
1
|
| 1 |
IC50 = 861 nM
|
|
|
|
CP0556201
|
methyl 5-[(2-cyclohexylacetyl)amino]-1-[(4-methoxyphenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C27H30N2O5
|
1
|
| 1 |
IC50 = 875 nM
|
|
|
|
CP0398068
|
tert-butyl 4-[[5-[(4-isoquinolin-5-ylsulfonyloxyphenyl)methyl]-2,4-dioxoimidazolidin-1-yl]methyl]piperidine-1-carboxylate
Show/Hide
|
C30H34N4O7S
|
1
|
| 1 |
IC50 = 885 nM
|
|
|
|
CP0476779
|
methyl 5-(adamantane-1-carbonylamino)-1-[(4-fluorophenyl)methyl]-2-oxoquinoline-3-carboxylate
Show/Hide
|
C29H29FN2O4
|
1
|
| 1 |
IC50 = 888 nM
|
|
|
|
CP0475275
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] 3-bromobenzenesulfonate
Show/Hide
|
C28H22BrClF3N3O4S
|
1
|
| 1 |
IC50 = 896 nM
|
|
|
|
CP0068447
|
(NE)-N-[(2-phenyltriazol-4-yl)methylidene]hydroxylamine
Show/Hide
|
C9H8N4O
|
1
|
| 1 |
IC50 = 897 nM
|
|
|
|
CP0379074
|
N-[2-(4-benzyl-1,4-diazepan-1-yl)-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
|
C23H26N4O3S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0423398
|
N'-(3,5-dichloropyridin-4-yl)-3-(4-fluorophenyl)propanehydrazide
Show/Hide
|
C14H12Cl2FN3O
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0526093
|
N'-(2,6-dimethylphenyl)-3-phenylpropanehydrazide
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0381973
|
[4-[[3-[1-(4-fluorobenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H27FN4O6S
|
1
|
| 1 |
IC50 = 913 nM
|
|
|
|
CP0218538
|
[1-(4-methoxyphenyl)triazol-4-yl]methanol
Show/Hide
|
C10H11N3O2
|
1
|
| 1 |
IC50 = 932 nM
|
|
|
|
CP0524671
|
N'-(3,5-dichloropyridin-4-yl)-7-phenylheptanehydrazide
Show/Hide
|
C18H21Cl2N3O
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0428808
|
US9409917, 87
Show/Hide
|
C20H24N4O4
|
1
|
| 1 |
IC50 = 978 nM
|
|
|
|
CP0417427
|
N-[1-[(Z)-[(cyanoamino)-(3-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C24H31N5O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0420687
|
[4-[[2,4-dioxo-6-[4-(2-phenylacetyl)piperazin-1-yl]pyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H29N5O6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0552760
|
(2,3-dichlorophenyl)-[3-phenyl-4-(3,3,3-trifluoropropyl)piperazin-1-yl]methanone
Show/Hide
|
C20H19Cl2F3N2O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0400695
|
tert-butyl 4-[2-[5-[(4-isoquinolin-5-ylsulfonyloxyphenyl)methyl]-2,4-dioxoimidazolidin-1-yl]ethyl]piperidine-1-carboxylate
Show/Hide
|
C31H36N4O7S
|
1
|
| 1 |
IC50 = 1010 nM
|
|
|
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CP0498612
|
(R)-(4-((1-methyl-1H-indol-3-yl)methyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C35H34N6O3
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0409310
|
US9409917, 48
Show/Hide
|
C16H15ClN2O2
|
1
|
| 1 |
IC50 = 1087 nM
|
|
|
|
CP0420957
|
N'-(3,5-dichloropyridin-4-yl)-1,2,3,4-tetrahydronaphthalene-2-carbohydrazide
Show/Hide
|
C16H15Cl2N3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0498292
|
3-(4-chlorophenyl)-N'-(3,5-dichloropyridin-4-yl)propanehydrazide
Show/Hide
|
C14H12Cl3N3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0537117
|
N'-(3,5-dichloropyridin-4-yl)-2-phenylacetohydrazide
Show/Hide
|
C13H11Cl2N3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0451496
|
US9409917, 44
Show/Hide
|
C21H18N2O3
|
1
|
| 1 |
IC50 = 1117 nM
|
|
|
|
CP0880833
|
13-Cyclohexylmethyl-2,3,9,10-tetramethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium chloride
Show/Hide
|
C28H34ClNO4
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0569568
|
N-(4-methyl-1,3-benzothiazol-2-yl)-3-(4-pyridin-4-ylpiperazin-1-yl)propanamide
Show/Hide
|
C20H23N5OS
|
1
|
| 1 |
IC50 = 1130 nM
|
|
|
|
CP0473061
|
(2S)-1-benzyl-N-[(2,4-dichlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C19H18Cl2N2O2
|
1
|
| 1 |
IC50 = 1130.3 nM
|
|
|
|
CP0507310
|
US9409917, 90
Show/Hide
|
C20H24N4O3
|
1
|
| 1 |
IC50 = 1149 nM
|
|
|
|
CP0455289
|
(R)-(4-(4-methylbenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl isoquinoline-5-carboxylate
Show/Hide
|
C33H31N5O3
|
1
|
| 1 |
IC50 = 1180 nM
|
|
|
|
CP0495552
|
US9409917, 53
Show/Hide
|
C17H14F4N2O3
|
1
|
| 1 |
IC50 = 1185 nM
|
|
|
|
CP0475817
|
N'-(3,5-dichloropyridin-4-yl)-5-phenylpentanehydrazide
Show/Hide
|
C16H17Cl2N3O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0498299
|
N'-(3,5-dichloropyridin-4-yl)-3-naphthalen-1-ylpropanehydrazide
Show/Hide
|
C18H15Cl2N3O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0417326
|
[4-[[6-(4-benzylpiperazin-1-yl)-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H29N5O5S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0492892
|
US9409917, 47
Show/Hide
|
C16H13F3N2O2
|
1
|
| 1 |
IC50 = 1248 nM
|
|
|
|
CP0933149
|
9-(4-tert-Butyl-benzyloxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C33H38INO4
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0443622
|
(R)-(4-(4-fluorobenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl isoquinoline-5-carboxylate
Show/Hide
|
C32H28FN5O3
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0572057
|
N-(4-methyl-1,3-benzothiazol-2-yl)-3-(4-pyrimidin-2-ylpiperazin-1-yl)propanamide
Show/Hide
|
C19H22N6OS
|
1
|
| 1 |
IC50 = 1330 nM
|
|
|
|
CP0461645
|
(S)-4-(3-(4-benzoylpiperazin-1-yl)-2-(benzyloxycarbonyl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C36H37N3O7S
|
1
|
| 1 |
IC50 = 1360 nM
|
|
|
|
CP0446967
|
N'-(3,5-dichloropyridin-4-yl)-3-(4-methylphenyl)propanehydrazide
Show/Hide
|
C15H15Cl2N3O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0494036
|
N'-(2,6-dichlorophenyl)-3-phenylpropanehydrazide
Show/Hide
|
C15H14Cl2N2O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0524670
|
N'-(3,5-dichloropyridin-4-yl)tricyclo[3.3.1.03,7]nonane-3-carbohydrazide
Show/Hide
|
C15H17Cl2N3O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0576607
|
N-(4-methyl-1,3-benzothiazol-2-yl)-3-(4-pyridin-2-ylpiperazin-1-yl)propanamide
Show/Hide
|
C20H23N5OS
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0498889
|
(R)-(4-(4-nitrobenzyl)-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl 1-methyl-1H-indole-3-carboxylate
Show/Hide
|
C32H30N6O5
|
1
|
| 1 |
IC50 = 1420 nM
|
|
|
|
CP0483532
|
[4-[3-[1-[4-(diethylamino)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C34H35N5O4S
|
1
|
| 1 |
IC50 = 1440 nM
|
|
|
|
CP0498888
|
(R)-(4-benzyl-8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl isoquinoline-5-carboxylate
Show/Hide
|
C32H29N5O3
|
1
|
| 1 |
IC50 = 1450 nM
|
|
|
|
CP0406570
|
US9409917, 117
Show/Hide
|
C16H15ClN2O3
|
1
|
| 1 |
IC50 = 1487 nM
|
|
|
|
CP0433925
|
N'-(3,5-dichloropyridin-4-yl)-3-(4-methoxyphenyl)propanehydrazide
Show/Hide
|
C15H15Cl2N3O2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0880835
|
9-(2,5-Dimethyl-benzyloxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C31H34INO4
|
1
|
| 1 |
IC50 = 1530 nM
|
|
|
|
CP0388062
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(tosyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C33H39N3O8S
|
1
|
| 1 |
IC50 = 1540 nM
|
|
|
|
CP0567825
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] methanesulfonate
Show/Hide
|
C23H21ClF3N3O4S
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
|
CP0490672
|
N-[1-[(Z)-[(cyanoamino)-(quinolin-8-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C26H30N6O3
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0542492
|
[4-[[3-(1-benzylpiperidin-4-yl)-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H30N4O5S
|
1
|
| 1 |
IC50 = 1620 nM
|
|
|
|
CP0381971
|
[4-[[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-2,5-dioxo-1-propylimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H32ClF3N4O6S
|
1
|
| 1 |
IC50 = 1670 nM
|
|
|
|
CP0472355
|
[4-[[3-[(1-benzylpiperidin-4-yl)methyl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C32H32N4O5S
|
1
|
| 1 |
IC50 = 1820 nM
|
|
|
|
CP0566495
|
N'-(3,5-dichloropyridin-4-yl)-6-phenylhexanehydrazide
Show/Hide
|
C17H19Cl2N3O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0459179
|
1-(2,3-dichlorophenyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]tetrazol-5-amine
Show/Hide
|
C15H10Cl2F3N5O
|
1
|
| 1 |
IC50 = 1905.46 nM
|
|
|
|
CP0398150
|
tert-butyl 4-[[3-(isoquinolin-5-ylmethyl)-5-[(4-isoquinolin-5-ylsulfonyloxyphenyl)methyl]-2,4-dioxoimidazolidin-1-yl]methyl]piperidine-1-carboxylate
Show/Hide
|
C40H41N5O7S
|
1
|
| 1 |
IC50 = 1970 nM
|
|
|
|
CP0455062
|
N-[1-[(Z)-[(cyanoamino)-(4-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C24H31N5O3
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0501714
|
(S)-4-(2-(benzyloxycarbonyl)-3-(4-(4-(dimethylamino)benzoyl)piperazin-1-yl)-3-oxopropyl)phenyl 4-methylbenzenesulfonate
Show/Hide
|
C37H40N4O7S
|
1
|
| 1 |
IC50 = 2010 nM
|
|
|
|
CP0420689
|
[4-[[2,4-dioxo-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]pyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H26F3N5O5S
|
1
|
| 1 |
IC50 = 2140 nM
|
|
|
|
CP0544800
|
3-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-N-(4-methyl-1,3-benzothiazol-2-yl)propanamide
Show/Hide
|
C19H29N5OS
|
1
|
| 1 |
IC50 = 2150 nM
|
|
|
|
CP0498953
|
[4-[[3-[1-(1-adamantylmethyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H40N4O5S
|
1
|
| 1 |
IC50 = 2290 nM
|
|
|
|
CP0437632
|
N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-thiophen-2-ylpyrrolidine-3-carboxamide
Show/Hide
|
C16H14Cl2N2O2S
|
1
|
| 1 |
IC50 = 2406 nM
|
|
|
|
CP0560195
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(4-(bromomethyl)phenylsulfonyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C33H38BrN3O8S
|
1
|
| 1 |
IC50 = 2460 nM
|
|
|
|
CP0436026
|
2-(2,4-dichlorophenyl)-N'-(3,5-dichloropyridin-4-yl)acetohydrazide
Show/Hide
|
C13H9Cl4N3O
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0399826
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-3,5-dimethoxybenzamide
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0916666
|
13-Ethyl-2,3,10-trimethoxy-9-(2-trifluoromethyl-benzyloxy)-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C30H29F3INO4
|
1
|
| 1 |
IC50 = 2560 nM
|
|
|
|
CP0917989
|
9-(4-Bromo-benzyloxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C29H29BrINO4
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0877314
|
9-(3-Chloro-benzyloxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C29H29ClINO4
|
1
|
| 1 |
IC50 = 2660 nM
|
|
|
|
CP0515408
|
US9409917, 58
Show/Hide
|
C18H16Cl2N2O2
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0489249
|
N'-(3,5-dichloropyridin-4-yl)bicyclo[2.2.1]heptane-2-carbohydrazide
Show/Hide
|
C13H15Cl2N3O
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0926173
|
9-(4-Benzyloxy-benzyloxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C36H36INO5
|
1
|
| 1 |
IC50 = 2810 nM
|
|
|
|
CP0515407
|
US9409917, 57
Show/Hide
|
C16H12F4N2O3
|
1
|
| 1 |
IC50 = 3065 nM
|
|
|
|
CP0467312
|
N-[1-[(Z)-[(cyanoamino)-(3-fluoroanilino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C23H28FN5O3
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0437638
|
(4S)-N-[(2,4-dichlorophenyl)methyl]-2-oxo-3-thiophen-2-yl-1,3-oxazolidine-4-carboxamide
Show/Hide
|
C15H12Cl2N2O3S
|
3
|
| 1 |
IC50 = 3168 nM
|
|
|
| 2 |
IC50 = 15126 nM
|
|
|
| 3 |
Ki = 3110 nM
|
|
|
|
CP0495549
|
US9409917, 10
Show/Hide
|
C16H22N2O3
|
1
|
| 1 |
IC50 = 3175 nM
|
|
|
|
CP0877313
|
9-(Biphenyl-4-ylmethoxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C35H34INO4
|
1
|
| 1 |
IC50 = 3220 nM
|
|
|
|
CP0512562
|
[4-[[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]-2,5-dioxo-1-propan-2-ylimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C35H32ClF3N4O6S
|
1
|
| 1 |
IC50 = 3240 nM
|
|
|
|
CP0486332
|
US9409917, 65
Show/Hide
|
C17H16N2O3
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0420688
|
[4-[[6-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C31H28FN5O5S
|
1
|
| 1 |
IC50 = 3430 nM
|
|
|
|
CP0525550
|
(2S)-1-[(2-chlorophenyl)methyl]-N-[(2,4-dichlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C19H17Cl3N2O2
|
1
|
| 1 |
IC50 = 3461.2 nM
|
|
|
|
CP0420264
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] naphthalene-1-sulfonate
Show/Hide
|
C32H25ClF3N3O4S
|
1
|
| 1 |
IC50 = 3520 nM
|
|
|
|
CP0461644
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(4-iodophenylsulfonyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C32H36IN3O8S
|
1
|
| 1 |
IC50 = 3540 nM
|
|
|
|
CP0521092
|
(2S,4E)-N-[(2,4-dichlorophenyl)methyl]-4-hydroxyimino-5-oxo-1-thiophen-2-ylpyrrolidine-2-carboxamide
Show/Hide
|
C16H13Cl2N3O3S
|
1
|
| 1 |
IC50 = 3724 nM
|
|
|
|
CP0531832
|
[4-[[3-[1-(3,4-dimethoxybenzoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H32N4O8S
|
1
|
| 1 |
IC50 = 3760 nM
|
|
|
|
CP0398153
|
[4-[[3-(isoquinolin-5-ylmethyl)-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C29H22N4O5S
|
1
|
| 1 |
IC50 = 3820 nM
|
|
|
|
CP0414520
|
US9409917, 63
Show/Hide
|
C14H17N3O3
|
1
|
| 1 |
IC50 = 3850 nM
|
|
|
|
CP0420956
|
N'-(3,5-dichloropyridin-4-yl)-2,3-dihydro-1H-indene-2-carbohydrazide
Show/Hide
|
C15H13Cl2N3O
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0562141
|
dimethyl (2S,4E)-4-[[(2,4-dichlorophenyl)methylamino]methylidene]-5-oxopyrrolidine-1,2-dicarboxylate
Show/Hide
|
C16H16Cl2N2O5
|
1
|
| 1 |
IC50 = 4267 nM
|
|
|
|
CP0469988
|
(R)-tert-butyl 4-(2-(6-benzyl-4-(cyclopropanecarbonyl)-8-oxo-5,6,7,8-tetrahydropyrazolo[4,3-e][1,4]diazepin-2(4H)-yl)ethyl)piperidine-1-carboxylate
Show/Hide
|
C29H39N5O4
|
1
|
| 1 |
IC50 = 4310 nM
|
|
|
|
CP0907745
|
9-(6-Chloro-pyridin-3-ylmethoxy)-13-ethyl-2,3,10-trimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C28H28ClIN2O4
|
1
|
| 1 |
IC50 = 4410 nM
|
|
|
|
CP0568244
|
US9409917, 64
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 4850 nM
|
|
|
|
CP0556734
|
[4-[[3-[1-(3-methylbutanoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C29H32N4O6S
|
1
|
| 1 |
IC50 = 4880 nM
|
|
|
|
CP0381959
|
[4-[[3-[2-(1-benzoylpiperidin-4-yl)ethyl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H32N4O6S
|
1
|
| 1 |
IC50 = 4990 nM
|
|
|
|
CP0535299
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzamide
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
IC50 = 5011.87 nM
|
|
|
|
CP0904641
|
13-Ethyl-2,3,10-trimethoxy-9-(2-methyl-benzyloxy)-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C30H32INO4
|
1
|
| 1 |
IC50 = 5020 nM
|
|
|
|
CP0949632
|
13-Ethyl-2,3,10-trimethoxy-9-(2-methyl-3-nitro-benzyloxy)-5,6-dihydro-isoquino[3,2-a]isoquinolinylium iodide
Show/Hide
|
C30H31IN2O6
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0460706
|
N-benzyl-1-(2,3-dichlorophenyl)-N-methyltetrazol-5-amine
Show/Hide
|
C15H13Cl2N5
|
1
|
| 1 |
IC50 = 5623.41 nM
|
|
|
|
CP0381960
|
[4-[[3-[1-(2,2-dimethylpropanoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C29H32N4O6S
|
1
|
| 1 |
IC50 = 5650 nM
|
|
|
|
CP0379051
|
[4-[[3-[2-(1-benzylpiperidin-4-yl)ethyl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C33H34N4O5S
|
1
|
| 1 |
IC50 = 5730 nM
|
|
|
|
CP0424996
|
E133
Show/Hide
|
C47H49N3O7S2
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0478104
|
(S)-tert-butyl 4-(2-(benzyloxycarbonyl)-3-(4-(4-fluorophenylsulfonyloxy)phenyl)propanoyl)piperazine-1-carboxylate
Show/Hide
|
C32H36FN3O8S
|
1
|
| 1 |
IC50 = 5880 nM
|
|
|
|
CP0539965
|
US9409917, 66
Show/Hide
|
C15H19N3O3
|
1
|
| 1 |
IC50 = 5880 nM
|
|
|
|
CP0424930
|
1-(2,4-dichlorophenyl)-2-(6-phenylpurin-9-yl)ethanone
Show/Hide
|
C19H12Cl2N4O
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0437636
|
(2S,4E)-N-[(2,4-dichlorophenyl)methyl]-4-[(4-methylpiperazin-1-yl)methylidene]-5-oxo-1-thiophen-2-ylpyrrolidine-2-carboxamide
Show/Hide
|
C22H24Cl2N4O2S
|
1
|
| 1 |
IC50 = 6947 nM
|
|
|
|
CP0455750
|
[4-[[3-[1-(2-methylpropanoyl)piperidin-4-yl]-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C28H30N4O6S
|
1
|
| 1 |
IC50 = 7220 nM
|
|
|
|
CP0498952
|
tert-butyl 4-[[(4S)-4-[(4-isoquinolin-5-ylsulfonyloxyphenyl)methyl]-2,5-dioxoimidazolidin-1-yl]methyl]piperidine-1-carboxylate
Show/Hide
|
C30H34N4O7S
|
1
|
| 1 |
IC50 = 7720 nM
|
|
|
|
CP0455054
|
N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-4-methoxybenzamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0504733
|
[4-[[3-(1-butanoylpiperidin-4-yl)-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C28H30N4O6S
|
1
|
| 1 |
IC50 = 8770 nM
|
|
|
|
CP0419747
|
[4-[[3-[(1-benzylpiperidin-4-yl)methyl]-1-(isoquinolin-5-ylmethyl)-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
Show/Hide
|
C42H39N5O5S
|
1
|
| 1 |
IC50 = 8960 nM
|
|
|
|
CP0507463
|
2-(6-chloropurin-9-yl)-1-(2,4-dichlorophenyl)ethanone
Show/Hide
|
C13H7Cl3N4O
|
2
|
| 1 |
IC50 = 9000 nM
|
|
|
| 2 |
IC50 = 13700 nM
|
|
|
|
CP0492878
|
US9409917, 116
Show/Hide
|
C17H12Cl2N2O3
|
1
|
| 1 |
IC50 = 9010 nM
|
|
|
|
CP0437635
|
(2S,4E)-N-[(2,4-dichlorophenyl)methyl]-4-(morpholin-4-ylmethylidene)-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C17H19Cl2N3O3
|
1
|
| 1 |
IC50 = 9557 nM
|
|
|
|
CP0468743
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] isoquinoline-5-carboxylate
Show/Hide
|
C32H24ClF3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0549245
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] benzoate
Show/Hide
|
C29H23ClF3N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0558630
|
[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] acetate
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C24H21ClF3N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0558631
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[4-[3-[1-[4-chloro-3-(trifluoromethyl)benzoyl]piperidin-4-yl]imidazol-4-yl]phenyl] thiophene-2-carboxylate
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C27H21ClF3N3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0437633
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(2S)-N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-phenylpyrrolidine-2-carboxamide
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C18H16Cl2N2O2
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1
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| 1 |
IC50 = 10000 nM
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CP0421614
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7-(2-chlorophenyl)sulfonyl-1,3-dimethylpurine-2,6-dione
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C13H11ClN4O4S
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1
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| 1 |
IC50 = 10000 nM
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CP0558206
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1-(4-chlorophenyl)-2-(6-chloropurin-9-yl)ethanone
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C13H8Cl2N4O
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1
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| 1 |
IC50 = 10000 nM
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CP0001282
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2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-ylamino)propane-1,3-diol
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C17H23IN4O4
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1
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| 1 |
IC50 > 10000 nM
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CP0424929
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2,6-dichloro-9-(2-chlorophenyl)sulfonylpurine
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C11H5Cl3N4O2S
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1
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| 1 |
IC50 = 10200 nM
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CP0398154
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[4-[[2,5-dioxo-3-(1-propanoylpiperidin-4-yl)imidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
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C27H28N4O6S
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1
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| 1 |
IC50 = 11700 nM
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CP0398067
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tert-butyl 4-[[3-(isoquinolin-5-ylmethyl)-4-[(4-isoquinolin-5-ylsulfonyloxyphenyl)methyl]-2,5-dioxoimidazolidin-1-yl]methyl]piperidine-1-carboxylate
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C40H41N5O7S
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1
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| 1 |
IC50 = 12000 nM
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CP0398151
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[4-[[(4S)-1-(isoquinolin-5-ylmethyl)-2,5-dioxoimidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
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C29H22N4O5S
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1
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| 1 |
IC50 = 12200 nM
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CP0381119
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(S)-tert-butyl 4-(2-(6-benzyl-4-(cyclopropanecarbonyl)-8-oxo-5,6,7,8-tetrahydropyrazolo[4,3-e][1,4]diazepin-2(4H)-yl)ethyl)piperidine-1-carboxylate
Show/Hide
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C29H39N5O4
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1
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| 1 |
IC50 = 13000 nM
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CP0421607
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1-(2,4-dichlorophenyl)-2-(2,6-dichloropurin-9-yl)ethanone
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C13H6Cl4N4O
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1
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| 1 |
IC50 = 13000 nM
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CP0549792
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3-[4-[3-(dimethylamino)propyl]piperazin-1-yl]-N-(4-methyl-1,3-benzothiazol-2-yl)propanamide
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C20H31N5OS
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1
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| 1 |
IC50 = 18100 nM
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CP0031968
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3-[4-(3-chloro-4-propan-2-yloxyanilino)-3-[(4-methylphenyl)methyl]-2,6-dioxo-1,3,5-triazin-1-yl]propanoic acid
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C23H25ClN4O5
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1
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| 1 |
IC50 > 30000 nM
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CP0032963
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US9150546, I-364
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C24H26ClFN4O5
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1
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| 1 |
IC50 > 30000 nM
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CP0435263
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N-[1-[(Z)-[(cyanoamino)-(2-methylanilino)methylidene]amino]-2,2-dimethylpropyl]-2-phenylacetamide
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C22H27N5O
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1
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| 1 |
IC50 = 31622.78 nM
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CP0549296
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(2-chlorophenyl)-(4-methyl-3-phenylpiperazin-1-yl)methanone
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C18H19ClN2O
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1
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| 1 |
IC50 = 48977.88 nM
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CP0575052
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(2-chlorophenyl)-(4-ethyl-3-phenylpiperazin-1-yl)methanone
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C19H21ClN2O
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1
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| 1 |
IC50 = 48977.88 nM
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CP0528230
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(2-chlorophenyl)-(2-phenyl-4-propylpiperazin-1-yl)methanone
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C20H23ClN2O
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1
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| 1 |
IC50 = 83176.38 nM
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CP0012869
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[[(2R,3S,4R,5R)-3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yloxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
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C12H16N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0014535
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[[(2R,3S,4R,5R)-4-amino-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
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C10H17N6O12P3
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1
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| 1 |
IC50 > 100000 nM
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CP0014825
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[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
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C10H15FN5O12P3
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1
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| 1 |
IC50 > 100000 nM
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CP0014826
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[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]-4-(4-methoxybenzoyl)oxyoxolan-3-yl] 4-methoxybenzoate
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C26H28N5O17P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015034
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[[(2R,3S,4R,5R)-5-(6-anilinopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
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C16H20N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015101
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((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyltriphosphate tetraammonium salt
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C11H18N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015206
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[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-sulfanylidene-3H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Show/Hide
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C10H15N4O13P3S
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1
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| 1 |
IC50 > 100000 nM
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CP0015207
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[[(2R,3S,4R,5R)-5-(6-amino-8-azidopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Show/Hide
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C10H15N8O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015268
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[[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Show/Hide
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C10H16N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015269
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[[(2R,3S,4R,5R)-5-[6-(butylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Show/Hide
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C14H24N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015315
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[[(2R,3S,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Show/Hide
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C17H22N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0015356
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US11185100, TABLE 14.4
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C10H14ClN4O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0639555
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[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(8-oxo-7H-purin-9-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]phosphono hydrogen phosphate
Show/Hide
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C10H15N4O14P3
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1
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| 1 |
IC50 > 100000 nM
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CP0639557
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Adenosine 5'-triphosphate derivative
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C11H18N5O13P3
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1
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| 1 |
IC50 > 100000 nM
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CP0379072
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N-[2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl]quinoline-5-sulfonamide
Show/Hide
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C21H21FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0379073
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N-[2-(4-benzylpiperazin-1-yl)-2-oxoethyl]naphthalene-1-sulfonamide
Show/Hide
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C23H25N3O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0379076
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N-[2-(4-naphthalen-1-ylpiperazin-1-yl)-2-oxoethyl]naphthalene-1-sulfonamide
Show/Hide
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C26H25N3O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0424355
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N-[2-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H23FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0427436
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N-[2-oxo-2-[4-(2-phenylethyl)piperazin-1-yl]ethyl]naphthalene-1-sulfonamide
Show/Hide
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C24H27N3O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0427438
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N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]naphthalene-1-sulfonamide
Show/Hide
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C22H23N3O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0428685
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N-[2-[4-(2,3-difluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H20F2N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0428687
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N-[2-oxo-2-[4-(3-phenylpropyl)piperazin-1-yl]ethyl]isoquinoline-5-sulfonamide
Show/Hide
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C24H28N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0431176
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N-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H21N5O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0431177
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N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H22N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0431178
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N-[2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl]quinoline-8-sulfonamide
Show/Hide
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C21H21FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0431179
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N-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethyl]-N-methylisoquinoline-5-sulfonamide
Show/Hide
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C22H23FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0433499
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N-[2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H23ClN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0433500
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N-[2-[4-(3,4-difluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H20F2N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0433501
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N-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H20F2N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0433502
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N-[2-[4-(3-fluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H21FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0433503
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N-[3-[4-(4-fluorophenyl)piperazin-1-yl]-3-oxopropyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H23FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0439813
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N-[2-[4-(4-iodophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H21IN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0461971
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N-[2-[4-(4-chlorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H21ClN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0464556
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N-[2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl]-N-methylisoquinoline-5-sulfonamide
Show/Hide
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C22H23FN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0495669
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N-[2-[4-(4-bromophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H21BrN4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0495671
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N-[2-oxo-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]isoquinoline-5-sulfonamide
Show/Hide
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C19H20N6O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0497123
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N-[2-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C23H26N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0501048
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N-[3-[4-(4-nitrophenyl)piperazin-1-yl]-3-oxopropyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H23N5O5S
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1
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| 1 |
IC50 > 1000 nM
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CP0503099
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N-[2-[4-(4-aminophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H23N5O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0522323
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N-[2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl]naphthalene-1-sulfonamide
Show/Hide
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C22H22FN3O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0522324
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N-[3-[4-(4-fluorophenyl)piperazin-1-yl]-3-oxopropyl]naphthalene-1-sulfonamide
Show/Hide
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C23H24FN3O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0525826
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N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H24N4O4S
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1
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| 1 |
IC50 > 1000 nM
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CP0553241
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N-[2-[4-(2,5-difluorophenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C21H20F2N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0553242
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N-[2-oxo-2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H21F3N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0553243
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N-[2-[4-(2-methylphenyl)piperazin-1-yl]-2-oxoethyl]isoquinoline-5-sulfonamide
Show/Hide
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C22H24N4O3S
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1
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| 1 |
IC50 > 1000 nM
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