Brief Information of the Compound and Protein
Compound Name
2-(1-adamantyl)-N-(2-phenylquinolin-5-yl)acetamide
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PubChem ID
CID: 145954765
Canonical SMILES
O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2nc(ccc12)-c1ccccc1
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Compound Formula C27H28N2O
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 447 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 434 nM
   TI
   LI
   LO
   TS