Brief Information of the Compound and Protein
Compound Name
6-chloro-N-[[(1S,3R)-1-hydroxy-3-methylcyclohexyl]methyl]-2-[(3R)-3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]quinoline-5-carboxamide
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PubChem ID
CID: 155522567
Canonical SMILES
C[C@@H]1CCC[C@@](O)(CNC(=O)c2c(Cl)ccc3nc(ccc23)N2CC[C@H](C2)C(C)(C)O)C1
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Compound Formula C25H34ClN3O3
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 14 nM
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