Brief Information of the Compound and Protein
Compound Name
2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]-N-[(2,3,4-trifluorophenyl)methyl]acetamide
    Show/Hide
PubChem ID
CID: 56679990
Canonical SMILES
CCn1c(CC(=O)NCc2ccc(F)c(F)c2F)c(C)nc1-c1ccc(F)cc1F
    Show/Hide
Compound Formula C21H18F5N3O
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 125.89 nM
   TI
   LI
   LO
   TS