Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[2-[1-(4-methylsulfonylbenzoyl)piperidin-4-yl]-3H-benzimidazol-5-yl] isoquinoline-5-sulfonate
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 PubChem ID
CID: 142737916
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(CC1)c1nc2cc(OS(=O)(=O)c3cccc4cnccc34)ccc2[nH]1
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Compound Formula C29H26N4O6S2
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 43 nM
   TI
   LI
   LO
   TS