Brief Information of the Compound and Protein
Compound Name
1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
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PubChem ID
CID: 53325874
Canonical SMILES
C[C@H](NC(NC#N)=Nc1cccc2ncccc12)c1ccccc1
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Compound Formula C19H17N5
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS