Brief Information of the Compound and Protein
Compound Name
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-1,4,4-trimethyl-5-oxopyrrolidine-2-carboxamide
    Show/Hide
PubChem ID
CID: 52943108
Canonical SMILES
CN1[C@@H](CC(C)(C)C1=O)C(=O)NCc1cccc(c1Cl)C(F)(F)F
    Show/Hide
Compound Formula C16H18ClF3N2O2
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
2
IC50 = 25.12 nM
   TI
   LI
   LO
   TS