Brief Information of the Compound and Protein
Compound Name
[4-[[6-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2,4-dioxopyrimidin-1-yl]methyl]phenyl] isoquinoline-5-sulfonate
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PubChem ID
CID: 71466214
SID: 163428884
Canonical SMILES
O=C(N1CCN(CC1)c1cc(=O)[nH]c(=O)n1Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C12CC3CC(CC(C3)C1)C2
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Compound Formula C35H37N5O6S
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS