Brief Information of the Compound and Protein
Compound Name
6-chloro-N-[[(1S)-3,3-difluoro-1-hydroxycyclohexyl]methyl]-2-[(3R)-3-fluoropyrrolidin-1-yl]quinoline-5-carboxamide
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PubChem ID
CID: 155517593
Canonical SMILES
O[C@@]1(CNC(=O)c2c(Cl)ccc3nc(ccc23)N2CC[C@@H](F)C2)CCCC(F)(F)C1
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Compound Formula C21H23ClF3N3O2
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 19 nM
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