Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-thiophen-3-ylpyrrolidine-2-carboxamide
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 PubChem ID
CID: 156020767
Canonical SMILES
Clc1ccc(CNC(=O)[C@@H]2CCC(=O)N2c2ccsc2)c(Cl)c1
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Compound Formula C16H14Cl2N2O2S
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 813.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 1251.2 nM
   TI
   LI
   LO
   TS
3
Ki = 256 nM
   TI
   LI
   LO
   TS