Brief Information of the Compound and Protein
Compound Name
N-Adamantan-2-ylmethyl-2-chloro-5-[3-(3-hydroxy-propylamino)-propyl]-benzamide hydrochloride
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PubChem ID
CID: 145949409
Canonical SMILES
Cl.O=C(NCC1C2CC3CC(C2)CC1C3)c1cc(CCCNCCCO)ccc1Cl
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Compound Formula C24H36Cl2N2O2
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 2 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS