Brief Information of the Compound and Protein
Compound Name
N-(3,4-dimethoxyphenyl)-4-[2-(2-methylanilino)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxamide
    Show/Hide
PubChem ID
CID: 166632456
Canonical SMILES
COc1ccc(NC(=O)N2CCN(CC2)c2c(Nc3ccccc3C)c(=O)c2=O)cc1OC
    Show/Hide
Compound Formula C24H26N4O5
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 302 nM
   TI
   LI
   LO
   TS