Brief Information of the Compound and Protein
Compound Name
methyl 4-[5-[[2-(1-adamantyl)acetyl]amino]quinolin-2-yl]benzoate
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PubChem ID
CID: 145961422
Canonical SMILES
COC(=O)c1ccc(cc1)-c1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2n1
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Compound Formula C29H30N2O3
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS