General Information of the Compound
| Compound ID |
CP0378258
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| Compound Name |
2-[2-(2,4-difluorophenyl)-3,5-dimethylimidazol-4-yl]-N-[(2,3,4-trifluorophenyl)methyl]acetamide
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| Structure |
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| Formula |
C20H16F5N3O
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| Molecular Weight |
409.358
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| Canonical SMILES |
Cc1nc(-c2ccc(F)cc2F)n(C)c1CC(=O)NCc1ccc(F)c(F)c1F
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| InChI |
InChI=1S/C20H16F5N3O/c1-10-16(28(2)20(27-10)13-5-4-12(21)7-15(13)23)8-17(29)26-9-11-3-6-14(22)19(25)18(11)24/h3-7H,8-9H2,1-2H3,(H,26,29)
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| InChIKey |
MWOODXQJJURYQI-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01449, P2X purinoceptor 7
Protein ID: PT03917, P2X purinoceptor 7