Brief Information of the Compound and Protein
Compound Name
(2S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-5-oxo-1-thiophen-2-ylpyrrolidine-2-carboxamide
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PubChem ID
CID: 156020491
Canonical SMILES
FC(F)(F)c1cccc(CNC(=O)[C@@H]2CCC(=O)N2c2cccs2)c1Cl
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Compound Formula C17H14ClF3N2O2S
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
2
IC50 = 217.8 nM
   TI
   LI
   LO
   TS
3
Ki = 44 nM
   TI
   LI
   LO
   TS