Brief Information of the Compound and Protein
Compound Name
[4-[[2,5-dioxo-3-[1-(tricyclo[3.3.1.03,7]nonane-3-carbonyl)piperidin-4-yl]imidazolidin-4-yl]methyl]phenyl] isoquinoline-5-sulfonate
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PubChem ID
CID: 118733192
Canonical SMILES
O=C(N1CCC(CC1)N1C(Cc2ccc(OS(=O)(=O)c3cccc4cnccc34)cc2)C(=O)NC1=O)C12CC3CC1CC(C2)C3
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Compound Formula C34H36N4O6S
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 69 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 49 nM
   TI
   LI
   LO
   TS