Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1-adamantylmethyl)-2-chloro-5-[3-(3-hydroxypropylamino)propyl]benzamide;hydrochloride
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 PubChem ID
CID: 10161380
SID: 15154540
Canonical SMILES
Cl.OCCCNCCCc1ccc(Cl)c(c1)C(=O)NCC12CC3CC(CC(C3)C1)C2
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Compound Formula C24H36Cl2N2O2
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.23 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.06 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM