| Compound ID |
Compound Name |
Compound Formula |
|
CP0175792
|
(8S,10R)-19-cyclohexyl-N-(dimethylsulfamoyl)-10-(3-ethyl-3,6-diazabicyclo[3.1.1]heptane-6-carbonyl)-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
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|
C36H45N5O5S
|
1
|
| 1 |
EC50 = 29000 nM
|
|
|
|
CP0481581
|
(8S,10R)-19-cyclohexyl-N-(dimethylsulfamoyl)-5-methoxy-10-(3-methyl-3,6-diazabicyclo[3.1.1]heptane-6-carbonyl)-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
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|
C35H43N5O5S
|
1
|
| 1 |
EC50 = 30000 nM
|
|
|
|
CP0010999
|
4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C18H12Cl2FN5O3S2
|
3
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
| 3 |
IC50 = 25000 nM
|
|
|
|
CP0523309
|
US8952169, 155
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|
C25H33FN2O5S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0389311
|
3-[3-(difluoromethoxy)pyridin-2-yl]-N-[2-pyridin-2-yl-3-(trifluoromethyl)phenyl]benzamide
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|
C25H16F5N3O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0422554
|
US8952169, 168
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|
C24H33FN2O5S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0380512
|
US8952169, 148
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|
C24H30FNO4S
|
2
|
| 1 |
IC50 = 26 nM
|
|
|
| 2 |
IC50 = 260 nM
|
|
|
|
CP0556756
|
US9012443, 1
Show/Hide
|
C23H16F3N5O2S2
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0472419
|
US8952169, 185
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|
C20H27FN2O4S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0116756
|
US8952169, 64
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|
C24H31FN2O4S
|
3
|
| 1 |
IC50 = 51 nM
|
|
|
| 2 |
IC50 = 51.5 nM
|
|
|
| 3 |
IC50 = 870 nM
|
|
|
|
CP0414704
|
US8952169, 47
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|
C24H31FN2O5S
|
1
|
| 1 |
IC50 = 60.6 nM
|
|
|
|
CP0270496
|
5-chloro-2-fluoro-4-[[(2S,3R)-2-phenyloxan-3-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
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|
C21H21ClFN3O3S2
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0385846
|
US8952169, 249
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|
C20H24F4N2O4S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0373945
|
[5-(4-tert-butylphenyl)furan-2-yl]-(4-cyclohexylpiperazin-1-yl)methanone
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|
C25H34N2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0406429
|
US8952169, 49
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|
C24H32FNO5S
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0550785
|
US8952169, 147
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|
C25H33FN2O5S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0149262
|
N-(7-(adamantan-1-ylmethoxy)-6-ethyl-[1,2,4]triazolo[4,3-a]-pyridin-3-yl)-cyclopropanesulfonamide
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|
C23H30N4O3S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0480174
|
(4-methoxy-3-pyrrolidin-1-ylphenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C28H32N4O3
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0520988
|
(4R)-4-[2-(4-fluorophenyl)-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
|
C25H18F4N2O3S2
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0422473
|
US8952169, 191
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|
C24H31FN2O4S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0539631
|
US8952169, 262
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|
C24H28F3NO4S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0469295
|
US8952169, 186
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|
C20H28FNO5S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0408067
|
3-amino-4-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-isoxazolyl-7-cinnolinesulfonamide
Show/Hide
|
C24H17ClFN5O4S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0908542
|
(R)-N-Benzyl-2-(4-benzylpiperazin-1-yl)-2-phenylacetamide
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|
C26H29N3O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0375415
|
US8952169, 169
Show/Hide
|
C25H33FN2O5S
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0520966
|
(4R)-4-[2-(6-fluoropyridin-3-yl)-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
|
C24H17F4N3O3S2
|
1
|
| 1 |
IC50 = 154 nM
|
|
|
|
CP0481484
|
US8952169, 60
Show/Hide
|
C22H28FNO4S
|
2
|
| 1 |
IC50 = 159 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0416407
|
US8952169, 446
Show/Hide
|
C21H25F4NO4S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0468444
|
US8952169, 269
Show/Hide
|
C21H27FN2O4S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0510322
|
[3-(dimethylamino)-4-methoxyphenyl]-[7-(trifluoromethoxy)spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl]methanone
Show/Hide
|
C26H27F3N4O3
|
1
|
| 1 |
IC50 = 181 nM
|
|
|
|
CP0559531
|
N-(6-fluoropyridin-2-yl)-4-(2-morpholino-4-(trifluoromethyl)phenyl)chroman-7-sulfonamide
Show/Hide
|
C25H23F4N3O4S
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
|
CP0037062
|
6-amino-2-[(4-tert-butylphenyl)methylsulfanyl]-3-methylpyrimidin-4-one
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|
C16H21N3OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0337526
|
2-N-[4-(4-chlorophenoxy)phenyl]-1,3,5-triazine-2,4-diamine
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|
C15H12ClN5O
|
3
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 3200 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0079810
|
2-(Dimethylamino)ethyl p-(butylamino)benzoate
Show/Hide
|
C15H24N2O2
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 650 nM
|
|
|
|
CP0236522
|
US9346798, 215
Show/Hide
|
C19H12F4N4O3S2
|
2
|
| 1 |
IC50 = 203 nM
|
|
|
| 2 |
IC50 = 320 nM
|
|
|
|
CP0383731
|
US9346798, 25
Show/Hide
|
C22H19F3N4O4S2
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0537598
|
[3-(dimethylamino)-4-methoxyphenyl]-[7-(trifluoromethyl)spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl]methanone
Show/Hide
|
C26H27F3N4O2
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0364729
|
3-[3-(difluoromethoxy)pyridin-2-yl]-N-[2-pyridin-3-yl-3-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C25H16F5N3O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0204852
|
4-[4-chloro-2-[3-(methylamino)-1,2-benzoxazol-5-yl]phenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H14ClF2N5O4S2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0362520
|
2-N-[4-[4-(trifluoromethoxy)phenoxy]phenyl]pyrimidine-2,4-diamine
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|
C17H13F3N4O2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0161806
|
5-chloro-4-(1,3-dioxolan-2-ylmethylamino)-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C13H13ClFN3O4S2
|
1
|
| 1 |
IC50 = 242 nM
|
|
|
|
CP0562237
|
4-(2-morpholino-4-(trifluoromethyl)phenyl)-N-(pyrimidin-4-yl)chroman-7-sulfonamide
Show/Hide
|
C24H23F3N4O4S
|
1
|
| 1 |
IC50 = 248 nM
|
|
|
|
CP0450589
|
US9346798, 38
Show/Hide
|
C23H21F3N4O3S2
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
|
CP0561723
|
(4S)-4-[[(2S)-6-amino-2-[[(2S)-5-carbamimidamido-2-[[(1R,4S,7S,13S,16R,21R,24S,27S,30S,33S,36S,39S,42R,45S,48S,51S,54S,57S,60R,65R,68S,71S,74S)-27,51,74-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-21-[[(2S)-2-[[(2S)-2-aminopent-4-ynoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-68-[(5-bromo-1H-indol-3-yl)methyl]-33-butyl-4,54-bis(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-45-(carboxymethyl)-39-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-30,36-bis(1H-indol-3-ylmethyl)-57-methyl-7,71-bis(2-methylpropyl)-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,67,70,73,76,81-tricosaoxo-18,19,62,63,78,79-hexathia-2,5,8,11,14,23,26,29,32,35,38,41,44,47,50,53,56,59,66,69,72,75,82-tricosazatricyclo[40.34.4.216,60]dooctacontane-65-carbonyl]amino]pentanoyl]amino]hexanoyl]amino]-5-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
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|
C162H245BrN48O40S6
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0387406
|
N-(7-((3r,5r,7r)-adamantan-1-ylmethoxy)-6-cyclopropyl-[1,2,4]-triazolo[4,3-a]pyridin-3-yl)methanesulfonamide
Show/Hide
|
C21H28N4O3S
|
1
|
| 1 |
IC50 = 265 nM
|
|
|
|
CP0081253
|
5-chloro-4-[(1,1-dioxothiolan-3-yl)methylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C14H15ClFN3O4S3
|
1
|
| 1 |
IC50 = 266 nM
|
|
|
|
CP0459561
|
N-[2-methyl-3-[[4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
Show/Hide
|
C24H25F3N6O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0351003
|
US10273214, Example 1563
Show/Hide
|
C15H19N3OS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0482986
|
US9346798, 26
Show/Hide
|
C22H16F3N5O3S2
|
1
|
| 1 |
IC50 = 306 nM
|
|
|
|
CP0055093
|
6-[4-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C14H7F6N3O
|
1
|
| 1 |
IC50 = 333 nM
|
|
|
|
CP0480175
|
[7-(difluoromethoxy)spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl]-[3-(dimethylamino)-4-methoxyphenyl]methanone
Show/Hide
|
C26H28F2N4O3
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0226083
|
5-chloro-4-[2-(1,4-dioxaspiro[4.5]decan-8-yl)ethylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C19H23ClFN3O4S2
|
1
|
| 1 |
IC50 = 348 nM
|
|
|
|
CP0402670
|
US9346798, 7
Show/Hide
|
C22H20F3N5O3S2
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0456798
|
US8952169, 221
Show/Hide
|
C21H26F4N2O4S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0132109
|
[3-(dimethylamino)-4-methoxyphenyl]-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C26H30N4O3
|
3
|
| 1 |
IC50 = 351 nM
|
|
|
| 2 |
IC50 = 572 nM
|
|
|
| 3 |
IC50 = 10485 nM
|
|
|
|
CP0382563
|
[3-(dimethylamino)-4-methoxyphenyl]-(8-fluoro-7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C26H29FN4O3
|
1
|
| 1 |
IC50 = 358 nM
|
|
|
|
CP0495159
|
2-N-[4-(2-chlorophenoxy)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C16H13ClN4O
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0562372
|
(4R)-4-[2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
|
C24H17F4N3O3S2
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0379741
|
US9346798, 218
Show/Hide
|
C19H12F4N4O3S2
|
2
|
| 1 |
IC50 = 385 nM
|
|
|
| 2 |
IC50 = 650 nM
|
|
|
|
CP0399104
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C184H273N53O45S6
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
|
CP0430560
|
N-[2-morpholin-4-yl-3-(trifluoromethyl)phenyl]-3-pyridin-2-ylbenzamide
Show/Hide
|
C23H20F3N3O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0859601
|
(R)-N-Benzyl-2-(4-(3-cyano-5-(trifluoromethoxy)benzoyl)piperazin-1-yl)-2-phenylacetamide
Show/Hide
|
C28H25F3N4O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0139237
|
2-N-[4-(4-methylphenoxy)phenyl]pyrazine-2,6-diamine
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0382562
|
(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-quinolin-2-ylmethanone
Show/Hide
|
C26H24N4O2
|
1
|
| 1 |
IC50 = 419 nM
|
|
|
|
CP0468157
|
US8952169, 150
Show/Hide
|
C24H30F2N2O4S
|
1
|
| 1 |
IC50 = 422 nM
|
|
|
|
CP0543534
|
US8952169, 146
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|
C21H25ClFNO4S
|
1
|
| 1 |
IC50 = 427 nM
|
|
|
|
CP0524285
|
US8952169, 233
Show/Hide
|
C24H27F4NO4S
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0529708
|
N-[2-(3-chloropyridin-2-yl)-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
Show/Hide
|
C25H14ClF6N3O
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0400085
|
1'-benzyl-7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
IC50 = 455 nM
|
|
|
|
CP0139238
|
2-N-[4-[4-(trifluoromethyl)phenoxy]phenyl]pyrazine-2,6-diamine
Show/Hide
|
C17H13F3N4O
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0139236
|
2-N-[4-(4-fluorophenoxy)phenyl]pyrazine-2,6-diamine
Show/Hide
|
C16H13FN4O
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0514966
|
US9346798, 211
Show/Hide
|
C20H18F3N3O4S2
|
1
|
| 1 |
IC50 = 471 nM
|
|
|
|
CP0574827
|
N-[2-pyridin-2-yl-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
Show/Hide
|
C25H15F6N3O
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0385065
|
US9012443, 38
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C19H12F3N3O3S2
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2
|
| 1 |
IC50 = 490 nM
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| 2 |
IC50 = 23000 nM
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CP0478700
|
US9212182, 981
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C26H18F3N3O5S
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1
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| 1 |
IC50 = 496 nM
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CP0383589
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US9346798, 209
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C21H20F3N3O5S2
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1
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| 1 |
IC50 = 497 nM
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CP0505570
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N-[2-methyl-3-[[4-[4-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
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C24H25F3N6O2
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1
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| 1 |
IC50 = 500 nM
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CP0444666
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2-N-[4-(4-chlorophenoxy)phenyl]pyrimidine-2,4-diamine
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C16H13ClN4O
|
1
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| 1 |
IC50 = 500 nM
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CP0013607
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2-methoxyacetic acid [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methyl-amino]ethyl]-6-fluoro-1-isopropyl-tetralin-2-yl] ester;hydrate;hydrochloride
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C29H38FN3O3
|
1
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| 1 |
IC50 = 500 nM
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CP0968775
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(R)-N-benzyl-2-(4-cyano-3-methoxyphenyl)-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)acetamide
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C28H26F2N4O3
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1
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| 1 |
IC50 = 500 nM
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CP0537887
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[3-(dimethylamino)-4-methoxyphenyl]-[(3'S,4R)-7-methoxy-3'-methylspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl]methanone
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C27H32N4O3
|
1
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| 1 |
IC50 = 519 nM
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CP0465219
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3-(3-chloropyridin-2-yl)-N-[2-pyridin-3-yl-3-(trifluoromethyl)phenyl]benzamide
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C24H15ClF3N3O
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1
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| 1 |
IC50 = 520 nM
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CP0527982
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US9546164, 100
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C25H29Cl2FN2O4S
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2
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| 1 |
IC50 = 551 nM
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| 2 |
IC50 = 1500 nM
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CP0413563
|
US9346798, 53
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C23H17F3N4O3S2
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1
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| 1 |
IC50 = 554 nM
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CP0455755
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[3-chloro-4-(dimethylamino)phenyl]-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
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C25H27ClN4O2
|
1
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| 1 |
IC50 = 572 nM
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CP0337527
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2-N-[4-(4-methylphenoxy)phenyl]pyrimidine-2,4-diamine
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C17H16N4O
|
1
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| 1 |
IC50 = 590 nM
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CP0543446
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4-[(1-benzhydrylpiperidin-4-yl)methoxy]-5-cyclopropyl-2-fluoro-N-methylsulfonylbenzamide
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C30H33FN2O4S
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1
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| 1 |
IC50 = 590 nM
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CP0227797
|
US9346798, 212
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C19H12ClF3N4O3S2
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2
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| 1 |
IC50 = 610 nM
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| 2 |
IC50 = 736 nM
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CP0559858
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(4R)-4-[2-(2-methyl-1,3-oxazol-4-yl)-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
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C23H18F3N3O4S2
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1
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| 1 |
IC50 = 629 nM
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CP0527452
|
US8952169, 217
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C20H24F3NO4S
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1
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| 1 |
IC50 = 630 nM
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CP0442949
|
US9346798, 29
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C22H17F3N6O3S2
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1
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| 1 |
IC50 = 634 nM
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CP0450578
|
US9346798, 204
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C20H18F3N3O5S2
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1
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| 1 |
IC50 = 637 nM
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CP0541440
|
US8952169, 57
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C22H24ClFN2O5S
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1
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| 1 |
IC50 = 653 nM
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CP0430612
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N-[2-(2-methylpyridin-3-yl)-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
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C26H17F6N3O
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1
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| 1 |
IC50 = 660 nM
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CP0486543
|
US8952169, 175
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C18H24FNO4S
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1
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| 1 |
IC50 = 670 nM
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CP0515514
|
US9346798, 202
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C21H20N4O3S2
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1
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| 1 |
IC50 = 686 nM
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CP0402805
|
US8952169, 86
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C22H29NO4S
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1
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| 1 |
IC50 = 700 nM
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CP0859594
|
(R)-N-(Cyclopropylmethyl)-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)-2-phenylacetamide
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C23H25F2N3O2
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2
|
| 1 |
IC50 = 710 nM
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| 2 |
IC50 = 7700 nM
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CP0539308
|
US8952169, 153
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C22H26F3NO4S
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1
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| 1 |
IC50 = 714 nM
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CP0273513
|
2-N-[4-(4-chlorophenoxy)phenyl]pyrazine-2,6-diamine
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C16H13ClN4O
|
1
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| 1 |
IC50 = 720 nM
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CP0450033
|
US9346798, 94
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C20H15F3N4O3S2
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1
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| 1 |
IC50 = 724 nM
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CP0392287
|
5-chloro-2-fluoro-4-[(4-hydroxycyclohexyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C16H19ClFN3O3S2
|
1
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| 1 |
IC50 = 730 nM
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CP0406908
|
US9346798, 54
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C22H16F3N5O3S2
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1
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| 1 |
IC50 = 731 nM
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CP0368162
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4-[(6a-hydroxy-1,2,3,4,5,6-hexahydropentalen-3a-yl)methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C18H21ClFN3O3S2
|
1
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| 1 |
IC50 = 750 nM
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CP0495226
|
4-(1-adamantylmethoxy)-5-cyclopropyl-2-fluoro-N-(oxetan-3-ylsulfonyl)benzamide
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C24H30FNO5S
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
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CP0460250
|
US8952169, 26
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C20H26ClFN2O4S
|
1
|
| 1 |
IC50 = 772 nM
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CP0495160
|
2-N-[4-(4-fluorophenoxy)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C16H13FN4O
|
1
|
| 1 |
IC50 = 780 nM
|
|
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CP0161804
|
5-chloro-2-fluoro-4-[3-(oxolan-3-yl)propylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C16H19ClFN3O3S2
|
1
|
| 1 |
IC50 = 800 nM
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CP0560065
|
(4R)-4-[2-(2-methylpyrazol-3-yl)-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
|
C23H19F3N4O3S2
|
1
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| 1 |
IC50 = 812 nM
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CP0081108
|
1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-isoxazolyl-3-oxo-2,3-dihydro-6-isoquinolinesulfonamide
Show/Hide
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C25H17ClFN3O5S
|
1
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| 1 |
IC50 = 820 nM
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CP0111016
|
N-[2-pyridin-3-yl-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
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C25H15F6N3O
|
1
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| 1 |
IC50 = 820 nM
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|
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CP0443400
|
US9346798, 97
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C20H15F3N4O3S2
|
1
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| 1 |
IC50 = 851 nM
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CP0522221
|
US9346798, 200
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C24H17FN4O3S2
|
1
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| 1 |
IC50 = 854 nM
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CP0419914
|
US9346798, 208
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C21H20F3N3O5S2
|
1
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| 1 |
IC50 = 896 nM
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CP0491025
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-39-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
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C183H275N51O45S7
|
1
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| 1 |
IC50 = 900 nM
|
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CP0455756
|
(3-chloro-4-methoxyphenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C24H24ClN3O3
|
1
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| 1 |
IC50 = 934 nM
|
|
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CP0527406
|
US8952169, 448
Show/Hide
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C20H25F3N2O4S
|
1
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| 1 |
IC50 = 940 nM
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|
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CP0402668
|
US9346798, 4
Show/Hide
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C20H15F3N6O3S2
|
1
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| 1 |
IC50 = 944 nM
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CP0429095
|
[4-(dimethylamino)phenyl]-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
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C25H28N4O2
|
1
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| 1 |
IC50 = 947 nM
|
|
|
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CP0385167
|
US8952169, 219
Show/Hide
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C24H28F4N2O4S
|
1
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| 1 |
IC50 = 950 nM
|
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CP0865077
|
(R)-N-Benzyl-2-(4-(2-chloro-5-fluorobenzoyl)piperazin-1-yl)-2-phenylacetamide
Show/Hide
|
C26H25ClFN3O2
|
1
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| 1 |
IC50 = 950 nM
|
|
|
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CP0490219
|
US9346798, 50
Show/Hide
|
C23H24F3N5O3S2
|
1
|
| 1 |
IC50 = 957 nM
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CP0033565
|
(+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol
Show/Hide
|
C32H41NO2
|
1
|
| 1 |
IC50 = 971 nM
|
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CP0465221
|
N-(2-morpholin-4-ylphenyl)-2-quinolin-8-yloxyacetamide
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 = 980 nM
|
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CP0559530
|
(4R)-4-[2-(4-methylpiperazin-1-yl)-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
|
C24H25F3N4O3S2
|
1
|
| 1 |
IC50 = 983 nM
|
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CP0398799
|
2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxy-1-morpholin-4-ylethanone
Show/Hide
|
C19H17F2N3O3
|
1
|
| 1 |
IC50 = 1000 nM
|
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CP0401788
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C180H273N53O44S7
|
2
|
| 1 |
IC50 = 1000 nM
|
|
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| 2 |
IC50 = 3500 nM
|
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CP0480141
|
(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-quinolin-6-ylmethanone
Show/Hide
|
C26H24N4O2
|
1
|
| 1 |
IC50 = 1034 nM
|
|
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CP0437467
|
(R)-4-(4'-Fluoro-5-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)-N-(pyrimidin-2-yl)chromane-7-sulfonamide
Show/Hide
|
C26H19F4N3O3S
|
1
|
| 1 |
IC50 = 1069 nM
|
|
|
|
CP0396426
|
US8952169, 8
Show/Hide
|
C18H23ClFNO4S
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0419558
|
US9346798, 203
Show/Hide
|
C20H18N4O3S2
|
1
|
| 1 |
IC50 = 1090 nM
|
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CP0087289
|
N-[2-methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
Show/Hide
|
C25H27F3N6O3
|
3
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 = 5200 nM
|
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|
| 3 |
IC50 > 10000 nM
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CP0241710
|
3-pyridin-2-yl-N-[2-pyridin-3-yl-3-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C24H16F3N3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0476325
|
3-chloro-5-[4-(5-cyclobutylsulfonyl-1H-1,2,4-triazol-3-yl)-5-fluoro-2-methoxyphenyl]-2-(2-methylpropoxy)pyridine
Show/Hide
|
C22H24ClFN4O4S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0463182
|
US8952169, 440
Show/Hide
|
C28H29FN2O4S
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 = 2540 nM
|
|
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CP0525973
|
4-(2-(6-methylpyridin-3-yl)-4-(trifluoromethyl)phenyl)-N-(pyrimidin-4-yl)chroman-7-sulfonamide
Show/Hide
|
C26H21F3N4O3S
|
1
|
| 1 |
IC50 = 1103 nM
|
|
|
|
CP0537599
|
(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-(4-methyl-2,3-dihydro-1,4-benzoxazin-6-yl)methanone
Show/Hide
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C26H28N4O3
|
1
|
| 1 |
IC50 = 1138 nM
|
|
|
|
CP0443395
|
US9346798, 89
Show/Hide
|
C20H14F3N5O3S
|
2
|
| 1 |
IC50 = 1140 nM
|
|
|
| 2 |
IC50 = 4600 nM
|
|
|
|
CP0465555
|
US9346798, 206
Show/Hide
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C19H16F3N3O4S2
|
1
|
| 1 |
IC50 = 1140 nM
|
|
|
|
CP0512725
|
US9346798, 49
Show/Hide
|
C19H13F3N4O3S2
|
2
|
| 1 |
IC50 = 1150 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0527104
|
(R)-4-(2-(2-methyloxazol-4-yl)-4-(trifluoromethyl)phenyl)-N-(pyrimidin-4-yl)chroman-7-sulfonamide
Show/Hide
|
C24H19F3N4O4S
|
1
|
| 1 |
IC50 = 1168 nM
|
|
|
|
CP0401673
|
(2-butyl-1,3-benzoxazol-5-yl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 = 1186 nM
|
|
|
|
CP0011846
|
1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one
Show/Hide
|
C21H27NO3
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0074870
|
4-amino-2-heptylsulfanyl-1H-pyrimidin-6-one
Show/Hide
|
C11H19N3OS
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0189297
|
4-[4-[(4-aminopyrimidin-2-yl)amino]phenoxy]benzonitrile
Show/Hide
|
C17H13N5O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0402672
|
US9346798, 45
Show/Hide
|
C24H22F3N5O3S
|
2
|
| 1 |
IC50 = 1200 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
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CP0561100
|
N-[2-(3-fluoropyridin-2-yl)-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
Show/Hide
|
C25H14F7N3O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0419557
|
US9346798, 199
Show/Hide
|
C24H17FN4O3S2
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0170209
|
2-N-[4-[4-(trifluoromethoxy)phenoxy]phenyl]pyrazine-2,6-diamine
Show/Hide
|
C17H13F3N4O2
|
3
|
| 1 |
IC50 = 1260 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
| 3 |
IC50 = 10000 nM
|
|
|
|
CP0572386
|
US9012443, 15
Show/Hide
|
C23H22N4O3S2
|
1
|
| 1 |
IC50 = 1290 nM
|
|
|
|
CP0326703
|
CHEMBL4092435
Show/Hide
|
C16H19ClFN3O3S2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0368164
|
5-chloro-2-fluoro-4-[[(2R,3R)-2-phenyloxan-3-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C21H21ClFN3O3S2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0476331
|
3-chloro-2-(2-chloro-5-methylphenoxy)-5-[4-[5-(cyclopropylmethylsulfonyl)-1H-1,2,4-triazol-3-yl]-2,5-difluorophenyl]pyridine
Show/Hide
|
C24H18Cl2F2N4O3S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0958974
|
(R)-N-Benzyl-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)-2-phenylacetamide
Show/Hide
|
C26H25F2N3O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0402713
|
US9346798, 217
Show/Hide
|
C19H15FN4O4S2
|
1
|
| 1 |
IC50 = 1310 nM
|
|
|
|
CP0516808
|
N-(6-fluoropyridin-2-yl)-4-(2-(6-methylpyridin-3-yl)-4-(trifluoromethyl)phenyl)chroman-7-sulfonamide
Show/Hide
|
C27H21F4N3O3S
|
1
|
| 1 |
IC50 = 1312 nM
|
|
|
|
CP0230236
|
N-(6-cyclopropyl-7-((3,5-dichlorophenoxy)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methanesulfonamide
Show/Hide
|
C17H16Cl2N4O3S
|
1
|
| 1 |
IC50 = 1313 nM
|
|
|
|
CP0396856
|
[4-(dimethylamino)-3-methoxyphenyl]-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 1329 nM
|
|
|
|
CP0383593
|
US9346798, 21
Show/Hide
|
C22H16F3N5O3S2
|
1
|
| 1 |
IC50 = 1330 nM
|
|
|
|
CP0204850
|
4-[2-(3-amino-1,2-benzoxazol-5-yl)-4-chlorophenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H12ClF2N5O4S2
|
1
|
| 1 |
IC50 = 1380 nM
|
|
|
|
CP0139235
|
2-N-[4-(4-chlorophenoxy)phenyl]pyridine-2,4-diamine
Show/Hide
|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0490228
|
US9346798, 96
Show/Hide
|
C20H15F3N4O3S2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0161803
|
5-chloro-2-fluoro-4-(oxolan-3-ylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C13H13ClFN3O3S2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0429094
|
4-[7-(trifluoromethoxy)spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl]benzonitrile
Show/Hide
|
C24H19F3N4O2
|
1
|
| 1 |
IC50 = 1452 nM
|
|
|
|
CP0465557
|
US9346798, 31
Show/Hide
|
C18H12F3N5O3S2
|
1
|
| 1 |
IC50 = 1460 nM
|
|
|
|
CP0083131
|
US9012443, 331
Show/Hide
|
C24H16ClFN4O3S2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0527984
|
US8952169, 154
Show/Hide
|
C25H33FN2O4S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0055808
|
3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
IC50 = 1520 nM
|
|
|
|
CP0464864
|
US9346798, 193
Show/Hide
|
C18H14ClF2N3O4S2
|
1
|
| 1 |
IC50 = 1560 nM
|
|
|
|
CP0929052
|
(S)-1-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)-4-methylpentan-2-amine
Show/Hide
|
C14H18ClN3O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0569914
|
4-[2-oxo-1-(2-piperidin-1-ylethyl)quinolin-6-yl]oxybenzonitrile
Show/Hide
|
C23H23N3O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0412673
|
US9346798, 192
Show/Hide
|
C18H13ClN4O3S2
|
1
|
| 1 |
IC50 = 1610 nM
|
|
|
|
CP0475982
|
(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-(1-methylindol-5-yl)methanone
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 = 1653 nM
|
|
|
|
CP0527510
|
2-N-[4-(3-chlorophenoxy)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C16H13ClN4O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0446259
|
4-[3-(2,4-dichlorophenyl)morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C18H14Cl2F2N4O4S2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0431904
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-1-isopropyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
|
C22H26ClN3O4S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0537886
|
(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-quinolin-7-ylmethanone
Show/Hide
|
C26H24N4O2
|
1
|
| 1 |
IC50 = 1732 nM
|
|
|
|
CP0139223
|
2-N-(4-phenoxyphenyl)pyrazine-2,6-diamine
Show/Hide
|
C16H14N4O
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0407456
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-naphthalen-1-yl-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C180H273N53O45S7
|
2
|
| 1 |
IC50 = 1800 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0315135
|
5-chloro-2-fluoro-4-[[(1S,3R)-3-hydroxycyclohexyl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H19ClFN3O3S2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0535522
|
3-chloro-5-[4-(5-cyclobutylsulfonyl-1H-1,2,4-triazol-3-yl)-2,5-difluorophenyl]-2-(2-methylpropoxy)pyridine
Show/Hide
|
C21H21ClF2N4O3S
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0570697
|
US9546164, 99
Show/Hide
|
C25H29Cl2FN2O4S
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0035893
|
(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine
Show/Hide
|
C21H26N2S2
|
1
|
| 1 |
IC50 = 1830 nM
|
|
|
|
CP0490227
|
US9346798, 93
Show/Hide
|
C20H15F3N4O3S2
|
1
|
| 1 |
IC50 = 1840 nM
|
|
|
|
CP0419501
|
US9346798, 43
Show/Hide
|
C18H13BrF3N3O3S2
|
1
|
| 1 |
IC50 = 1850 nM
|
|
|
|
CP0515265
|
US9346798, 3
Show/Hide
|
C21H17F3N6O3S2
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
|
CP0545928
|
US9346798, 198
Show/Hide
|
C24H17FN4O3S2
|
1
|
| 1 |
IC50 = 1880 nM
|
|
|
|
CP0303021
|
US8952169, 6
Show/Hide
|
C19H23ClFNO4S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0419999
|
6-[4-(trifluoromethoxy)phenyl]-2H-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C13H8F3N3O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0459472
|
2-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C17H12F3N5O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0069381
|
4-[(4-aminocyclohexyl)methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H20ClFN4O2S2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0508108
|
5-chloro-2-fluoro-N-(5-fluoro-1,3-thiazol-2-yl)-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)benzenesulfonamide
Show/Hide
|
C17H19ClF2N4O2S2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0334669
|
5-chloro-4-[(2,6-dimethyloxan-4-yl)methylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H21ClFN3O3S2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0402877
|
3-[3-(difluoromethyl)pyridin-2-yl]-N-[2-pyridin-2-yl-3-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C25H16F5N3O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0467505
|
US8952169, 61
Show/Hide
|
C19H24BrNO4S
|
1
|
| 1 |
IC50 = 1950 nM
|
|
|
|
CP0419532
|
US9346798, 182
Show/Hide
|
C19H16F3N3O4S2
|
2
|
| 1 |
IC50 = 1990 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
|
CP0139222
|
2-N-[4-(4-cyclopropylphenoxy)phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C19H18N4O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0409171
|
5-fluoro-1-(2-fluorophenyl)-3-(2-imidazol-1-ylethoxy)indazole
Show/Hide
|
C18H14F2N4O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0226082
|
5-chloro-2-fluoro-4-[2-(oxan-3-yl)ethylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H19ClFN3O3S2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0017968
|
3-cyano-4-[2-[2-[(2-piperidin-4-ylethylamino)methyl]pyridin-4-yl]-4-[3-(trifluoromethyl)phenyl]phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C35H32F3N7O3S2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0516666
|
US9346798, 174
Show/Hide
|
C19H16N4O3S2
|
1
|
| 1 |
IC50 = 2010 nM
|
|
|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0465556
|
US9346798, 216
Show/Hide
|
C19H12F4N4O3S2
|
2
|
| 1 |
IC50 = 2100 nM
|
|
|
| 2 |
IC50 = 5730 nM
|
|
|
|
CP0399535
|
[3-(dimethylamino)-4-methoxyphenyl]-[7-(2-methoxyethoxy)spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl]methanone
Show/Hide
|
C28H34N4O4
|
1
|
| 1 |
IC50 = 2216 nM
|
|
|
|
CP0418362
|
US9346798, 86
Show/Hide
|
C24H22F3N5O3S
|
1
|
| 1 |
IC50 = 2260 nM
|
|
|
|
CP0450991
|
2-N-[4-(4-chlorophenoxy)-3-methylphenyl]pyrimidine-2,4-diamine
Show/Hide
|
C17H15ClN4O
|
1
|
| 1 |
IC50 = 2270 nM
|
|
|
|
CP0402714
|
US9346798, 6
Show/Hide
|
C27H28F3N5O5S2
|
1
|
| 1 |
IC50 = 2290 nM
|
|
|
|
CP0401147
|
[5-(4-chlorophenyl)furan-2-yl]-(4-cyclohexylpiperazin-1-yl)methanone
Show/Hide
|
C21H25ClN2O2
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0519233
|
US9346798, 124
Show/Hide
|
C19H16N4O3S2
|
1
|
| 1 |
IC50 = 2330 nM
|
|
|
|
CP0528190
|
4-[6-(3,5-dichlorophenoxy)-5-(trifluoromethyl)pyridin-3-yl]-3-methoxy-N-methylsulfonylbenzamide
Show/Hide
|
C21H15Cl2F3N2O5S
|
1
|
| 1 |
IC50 = 2350 nM
|
|
|
|
CP0539179
|
5-chloro-2-fluoro-4-[2-(oxan-4-yl)ethylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H19ClFN3O3S2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0389306
|
N-[2-(2-methoxypyridin-3-yl)-3-(trifluoromethyl)phenyl]-3-pyridin-2-ylbenzamide
Show/Hide
|
C25H18F3N3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0859676
|
(R)-N-Benzyl-2-(6-(2-chloro-5-fluorobenzoyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-phenylacetamide
Show/Hide
|
C27H25ClFN3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0378594
|
[3-(dimethylamino)-4-methoxyphenyl]-(7'-methoxyspiro[1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-5,4'-5H-pyrrolo[1,2-a]quinoxaline]-2-yl)methanone
Show/Hide
|
C28H32N4O3
|
1
|
| 1 |
IC50 = 2450 nM
|
|
|
|
CP0561482
|
US9012443, 326
Show/Hide
|
C21H16F3N3O3S2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0401782
|
2-benzyl-5-[1-(2-fluorophenyl)indazol-4-yl]-3,3a,6,6a-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-4-one
Show/Hide
|
C26H23FN4O
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0420000
|
2-[(4-methyl-1,3-oxazol-2-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C18H13F3N4O3
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0459471
|
2-[(5-methyl-1,3-oxazol-2-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C18H13F3N4O3
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0525260
|
US9346798, 141
Show/Hide
|
C20H17N5O3S2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0528189
|
4-(5-chloro-6-((2S)-2-(1- methylethyl)-1-pyrrolidinyl)-3- pyridinyl)-3-methoxy-N- (methylsulfonyl)benzamide
Show/Hide
|
C21H26ClN3O4S
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0525449
|
(R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl)phenyl)-N-(pyrimidin-4-yl)chroman-7-sulfonamide
Show/Hide
|
C25H18F4N4O3S
|
1
|
| 1 |
IC50 = 2516 nM
|
|
|
|
CP0487022
|
(3,3-Diphenyl-propyl)-(1-methyl-2-phenyl-ethyl)-amine
Show/Hide
|
C24H27N
|
1
|
| 1 |
IC50 = 2520 nM
|
|
|
|
CP0419961
|
US8952169, 43
Show/Hide
|
C21H28N2O4S
|
1
|
| 1 |
IC50 = 2580 nM
|
|
|
|
CP0086690
|
4-[[(3S,4R)-4-(4-chlorophenyl)-1-(2,2,2-trifluoroethyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H20ClF5N4O3S2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0437054
|
4-[(4-aminocyclohexyl)methylamino]-5-chloro-2-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C15H19ClFN5O2S2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0530961
|
5-[4-[5-(azetidin-1-ylsulfonyl)-1H-1,2,4-triazol-3-yl]-2-methoxyphenyl]-3-chloro-2-(2-methylpropoxy)pyridine
Show/Hide
|
C21H24ClN5O4S
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0383580
|
US9346798, 63
Show/Hide
|
C23H21F3N4O3S2
|
1
|
| 1 |
IC50 = 2670 nM
|
|
|
|
CP0850433
|
(3S)-3-amino-4-[[(1R,4S,10S,13R,16S,19S,22R,25R,30R,33S,36R,39R,42S,45S,48R,51S,54S,57R,60S,63R,69S,72S,77R,80S,86R,89S,92R,95R)-30-[[(2R)-6-amino-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2R)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C187H281N55O46S7
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2
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| 1 |
IC50 = 2700 nM
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| 2 |
IC50 > 5000 nM
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CP0513544
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5-chloro-2-fluoro-4-[(4-oxocyclohexyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C16H17ClFN3O3S2
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1
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| 1 |
IC50 = 2700 nM
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CP0465222
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3-[3-(difluoromethyl)pyridin-2-yl]-N-[2-pyridin-3-yl-3-(trifluoromethyl)phenyl]benzamide
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C25H16F5N3O
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1
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| 1 |
IC50 = 2700 nM
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CP0561474
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US9012443, 319
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C20H13F4N3O3S2
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1
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| 1 |
IC50 = 2790 nM
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CP0559664
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(1S)-1-[2-morpholin-4-yl-4-(trifluoromethyl)phenyl]-N-pyrimidin-2-yl-2,3-dihydro-1H-indene-5-sulfonamide
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C24H23F3N4O3S
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1
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| 1 |
IC50 = 2792 nM
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CP0383166
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1-[2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxyethyl]imidazolidin-2-one
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C18H16F2N4O2
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1
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| 1 |
IC50 = 2800 nM
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CP0475983
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(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-(1-methylindazol-5-yl)methanone
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C25H25N5O2
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1
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| 1 |
IC50 = 2811 nM
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CP0378593
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(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-quinolin-5-ylmethanone
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C26H24N4O2
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1
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| 1 |
IC50 = 2938 nM
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CP0327618
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2-N-[4-(4-cyclopropylphenoxy)phenyl]pyrazine-2,6-diamine
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C19H18N4O
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1
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| 1 |
IC50 = 3000 nM
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CP0407729
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2-[(4-cyclopropyl-1,3-oxazol-2-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
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C20H15F3N4O3
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1
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| 1 |
IC50 = 3000 nM
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CP0924346
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(R)-2-(4-(3,5-Difluorobenzoyl)piperazin-1-yl)-2-phenyl-N-(6-(2,2,2-trifluoroethoxy)pyridin3-yl)acetamide
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C26H23F5N4O3
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1
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| 1 |
IC50 = 3000 nM
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CP0402709
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US9346798, 111
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C17H15ClN4O4S2
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1
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| 1 |
IC50 = 3030 nM
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CP0482013
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[3-(dimethylamino)-4-methoxyphenyl]-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-azepane]-1'-yl)methanone
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C27H32N4O3
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1
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| 1 |
IC50 = 3069 nM
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CP0396347
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(4S)-4-[[(2S)-6-amino-2-[[(2S)-5-carbamimidamido-2-[[(1R,4S,7S,13S,16R,21R,24S,27S,30S,33S,36S,39S,42R,45S,48S,51S,54S,57S,60R,65R,68S,71S,74S)-27,51,74-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-21-[[(2S)-2-[[(2S)-2-aminopent-4-ynoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-33-butyl-4,54-bis(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-45-(carboxymethyl)-39-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-30,36,68-tris(1H-indol-3-ylmethyl)-57-methyl-7,71-bis(2-methylpropyl)-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,67,70,73,76,81-tricosaoxo-18,19,62,63,78,79-hexathia-2,5,8,11,14,23,26,29,32,35,38,41,44,47,50,53,56,59,66,69,72,75,82-tricosazatricyclo[40.34.4.216,60]dooctacontane-65-carbonyl]amino]pentanoyl]amino]hexanoyl]amino]-5-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
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C162H246N48O40S6
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1
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| 1 |
IC50 = 3072 nM
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CP0390679
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1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(pyridin-4-yl)imidazolidin-2-one
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C21H16FN5O
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1
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| 1 |
IC50 = 3100 nM
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CP0859674
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(R)-N-Benzyl-2-(4-(3-cyano-5-fluorobenzoyl)piperazin-1-yl)-2-phenylacetamide
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C27H25FN4O2
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1
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| 1 |
IC50 = 3100 nM
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CP0460598
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4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-methylsulfonyl-3-(trifluoromethyl)benzamide
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C18H18ClF3N2O4S
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1
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| 1 |
IC50 = 3100 nM
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CP0450579
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US9346798, 207
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C21H20F3N3O5S2
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1
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| 1 |
IC50 = 3110 nM
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CP0418146
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US9346798, 163
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C18H16ClN3O3S2
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1
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| 1 |
IC50 = 3140 nM
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CP0512329
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US9346798, 184
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C19H13F3N4O3S2
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1
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| 1 |
IC50 = 3170 nM
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CP0447928
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33,54-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C182H272N54O45S7
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2
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| 1 |
IC50 = 3200 nM
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| 2 |
IC50 > 5000 nM
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CP0929051
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(R)-1-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)-4-methylpentan-2-amine
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C14H18ClN3O
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1
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| 1 |
IC50 = 3200 nM
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CP0241749
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5-chloro-4-(1,4-dioxan-2-ylmethylamino)-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C14H15ClFN3O4S2
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1
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| 1 |
IC50 = 3200 nM
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CP0315136
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5-chloro-4-(1,4-dioxaspiro[4.5]decan-8-ylmethylamino)-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C18H21ClFN3O4S2
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1
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| 1 |
IC50 = 3200 nM
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CP0493670
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5-chloro-2-fluoro-4-(oxolan-3-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C14H15ClFN3O3S2
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1
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| 1 |
IC50 = 3200 nM
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CP0480173
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[3-(dimethylamino)-4-methoxyphenyl]-[(2'R,4S)-7-methoxy-2'-methylspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl]methanone
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C27H32N4O3
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1
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| 1 |
IC50 = 3261 nM
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CP0447623
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2-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C17H12F3N5O3
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1
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| 1 |
IC50 = 3300 nM
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CP0383711
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US9346798, 113
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C19H16F3N3O4S2
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1
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| 1 |
IC50 = 3370 nM
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CP0390699
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1-[2-[1-(2,4-difluorophenyl)-5-fluoroindazol-3-yl]oxyethyl]imidazolidin-2-one
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C18H15F3N4O2
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1
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| 1 |
IC50 = 3400 nM
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CP0399109
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-4,89-bis(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H269N53O45S8
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1
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| 1 |
IC50 = 3400 nM
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CP0566780
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-89-(1H-indol-2-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C182H272N54O45S6
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1
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| 1 |
IC50 = 3400 nM
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CP0465720
|
4-[(6a-methyl-2,3,4,5-tetrahydrofuro[2,3-b]furan-3a-yl)methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C17H19ClFN3O4S2
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1
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| 1 |
IC50 = 3400 nM
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|
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CP0479356
|
US9346798, 161
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C21H24N4O3S2
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1
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| 1 |
IC50 = 3490 nM
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CP0531240
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US8952169, 198
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C22H25F4NO4S
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1
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| 1 |
IC50 = 3500 nM
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CP0401845
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-42,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H276N56O44S7
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1
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| 1 |
IC50 = 3500 nM
|
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CP0549361
|
2-[[3-(2,6-dichlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C22H12Cl2F3N5O3
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1
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| 1 |
IC50 = 3500 nM
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CP0465721
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5-chloro-2-fluoro-4-[[(1S,3S)-3-hydroxycyclohexyl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C16H19ClFN3O3S2
|
1
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| 1 |
IC50 = 3500 nM
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|
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CP0418354
|
US9346798, 44
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C24H23F3N4O3S2
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1
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| 1 |
IC50 = 3590 nM
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|
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CP0419537
|
US9346798, 194
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C19H16N4O3S2
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1
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| 1 |
IC50 = 3590 nM
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CP0534548
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33,42-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C183H274N54O44S7
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1
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| 1 |
IC50 = 3600 nM
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CP0840655
|
5-Chloro-2-fluoro-4-(((4-(methoxyimino)cyclohexyl)methyl)amino)-N-(thiazol-2-yl)benzenesulfonamide
Show/Hide
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C17H20ClFN4O3S2
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1
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| 1 |
IC50 = 3600 nM
|
|
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CP0419535
|
US9346798, 188
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C18H13FN4O3S2
|
1
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| 1 |
IC50 = 3620 nM
|
|
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CP0485510
|
US9346798, 128
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C19H13F3N4O4S2
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1
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| 1 |
IC50 = 3690 nM
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CP0472263
|
N-cyclopropylsulfonyl-5-fluoro-1-methyl-3-[6-(2-methylpropoxy)pyridin-3-yl]indole-6-carboxamide
Show/Hide
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C22H24FN3O4S
|
2
|
| 1 |
IC50 = 3697 nM
|
|
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| 2 |
IC50 = 3700 nM
|
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CP0527509
|
2-N-[4-(4-chloro-N-methylanilino)phenyl]pyrimidine-2,4-diamine
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C17H16ClN5
|
1
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| 1 |
IC50 = 3700 nM
|
|
|
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CP0278751
|
BEPRIDIL HYDROCHLORIDE
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C24H34N2O
|
1
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| 1 |
IC50 = 3700 nM
|
|
|
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CP0393631
|
5-chloro-2-fluoro-4-[2-(oxan-2-yl)ethylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H19ClFN3O3S2
|
1
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| 1 |
IC50 = 3700 nM
|
|
|
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CP0565259
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-methylsulfonyl-3-(trifluoromethoxy)benzamide
Show/Hide
|
C18H18ClF3N2O5S
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0574410
|
1-(2,6-diethylphenyl)-3-(N'-ethylcarbamimidoyl)urea
Show/Hide
|
C14H22N4O
|
1
|
| 1 |
IC50 = 3750 nM
|
|
|
|
CP0501029
|
US8952169, 92
Show/Hide
|
C20H24ClF3N2O4S
|
1
|
| 1 |
IC50 = 3760 nM
|
|
|
|
CP0405660
|
N-cyclopropylsulfonyl-5-fluoro-1-methyl-3-[4-(trifluoromethyl)phenyl]indole-6-carboxamide
Show/Hide
|
C20H16F4N2O3S
|
2
|
| 1 |
IC50 = 3800 nM
|
|
|
| 2 |
IC50 = 3818 nM
|
|
|
|
CP0512740
|
US9346798, 84
Show/Hide
|
C17H13F2N3O3S2
|
1
|
| 1 |
IC50 = 3810 nM
|
|
|
|
CP0495517
|
US9346798, 138
Show/Hide
|
C18H18N4O4S2
|
1
|
| 1 |
IC50 = 3830 nM
|
|
|
|
CP0334670
|
5-chloro-2-fluoro-4-(oxan-2-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C15H17ClFN3O3S2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0199853
|
3-(3-aminopyridin-2-yl)-N-[2-pyridin-3-yl-3-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C24H17F3N4O
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0431908
|
1-Methyl-N-(thiophen-2-ylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-1H-indole-6-carboxamide
Show/Hide
|
C21H15F3N2O3S2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0545193
|
US9546164, 209
Show/Hide
|
C26H31Cl2FN2O4S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0383585
|
US9346798, 156
Show/Hide
|
C18H16ClN3O3S2
|
1
|
| 1 |
IC50 = 3930 nM
|
|
|
|
CP0455754
|
(4-chlorophenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C23H22ClN3O2
|
1
|
| 1 |
IC50 = 3949 nM
|
|
|
|
CP0403202
|
2-[(3-ethyl-1,2,4-oxadiazol-5-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C18H14F3N5O3
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0326736
|
5-chloro-2-fluoro-4-(oxan-4-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C15H17ClFN3O3S2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0541470
|
3-chloro-2-(2-chloro-4-fluorophenoxy)-5-[4-[5-(cyclopropylmethylsulfonyl)-1H-1,2,4-triazol-3-yl]-2,5-difluorophenyl]pyridine
Show/Hide
|
C23H15Cl2F3N4O3S
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0369849
|
4-[[(1S,6R)-6-amino-2-(4-fluorophenyl)cyclohex-2-en-1-yl]methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide;hydrochloride
Show/Hide
|
C22H22Cl2F2N4O2S2
|
1
|
| 1 |
IC50 = 4020 nM
|
|
|
|
CP0490218
|
US9346798, 5
Show/Hide
|
C18H13ClF3N3O3S2
|
1
|
| 1 |
IC50 = 4030 nM
|
|
|
|
CP0462740
|
US9051311, 21
Show/Hide
|
C23H18F3N5O2S2
|
1
|
| 1 |
IC50 = 4080 nM
|
|
|
|
CP0566110
|
(4R)-4-[2-piperazin-1-yl-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide
Show/Hide
|
C23H23F3N4O3S2
|
1
|
| 1 |
IC50 = 4089 nM
|
|
|
|
CP0873914
|
(R)-N-Benzyl-2-(8-(2-chloro-5-fluorobenzoyl)-3,8-diazabicyclo[3.2.1]octan-3-yl)-2-phenylacetamide
Show/Hide
|
C28H27ClFN3O2
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0381363
|
(3-methoxyphenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 4325 nM
|
|
|
|
CP0553938
|
[3-(dimethylamino)phenyl]-spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-ylmethanone
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
IC50 = 4384 nM
|
|
|
|
CP0380327
|
4-[1-(2-fluorophenyl)indazol-4-yl]-1-[2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethyl]piperazin-2-one
Show/Hide
|
C23H23F2N5O2
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0540507
|
4-[(2S,3S)-3-(3,5-dichlorophenyl)-6,6-dimethylmorpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H18Cl2F2N4O4S2
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0410382
|
(3-chlorophenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C23H22ClN3O2
|
1
|
| 1 |
IC50 = 4418 nM
|
|
|
|
CP0442952
|
US9346798, 69
Show/Hide
|
C19H15N5O3S2
|
1
|
| 1 |
IC50 = 4440 nM
|
|
|
|
CP0420126
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,83S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,83,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C180H280N56O45S7
|
2
|
| 1 |
IC50 = 4500 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0513543
|
5-chloro-2-fluoro-4-(oxolan-2-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C14H15ClFN3O3S2
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0410384
|
4-[(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methyl]benzonitrile
Show/Hide
|
C24H24N4O
|
1
|
| 1 |
IC50 = 4577 nM
|
|
|
|
CP0218570
|
1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
Show/Hide
|
C15H15ClN2O2
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0084730
|
Oliceridine
Show/Hide
|
C22H30N2O2S
|
2
|
| 1 |
IC50 = 4700 nM
|
|
|
| 2 |
IC50 = 16500 nM
|
|
|
|
CP0218595
|
5-chloro-2-fluoro-4-[(3-oxocyclohexyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H17ClFN3O3S2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0531785
|
US9012443, 521
Show/Hide
|
C23H15ClFN5O3S2
|
1
|
| 1 |
IC50 = 4750 nM
|
|
|
|
CP0412665
|
US9346798, 32
Show/Hide
|
C19H14ClF3N4O3S
|
1
|
| 1 |
IC50 = 4770 nM
|
|
|
|
CP0523935
|
US9346798, 56
Show/Hide
|
C18H13ClN4O3S2
|
1
|
| 1 |
IC50 = 4790 nM
|
|
|
|
CP0441213
|
US9346798, 201
Show/Hide
|
C24H20FN3O4S2
|
1
|
| 1 |
IC50 = 4830 nM
|
|
|
|
CP0495508
|
US9346798, 68
Show/Hide
|
C20H16N4O3S2
|
1
|
| 1 |
IC50 = 4830 nM
|
|
|
|
CP0513093
|
4-[7-(trifluoromethyl)spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl]benzonitrile
Show/Hide
|
C24H19F3N4O
|
1
|
| 1 |
IC50 = 4871 nM
|
|
|
|
CP0427952
|
(2-methoxyphenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 4891 nM
|
|
|
|
CP0555575
|
4-[2-(4-aminocyclohexyl)ethylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H22ClFN4O2S2
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0412334
|
US9346798, 41
Show/Hide
|
C17H14ClN3O3S2
|
1
|
| 1 |
IC50 = 4930 nM
|
|
|
|
CP0486876
|
US9783527, Example 2
Show/Hide
|
C21H21FN4O3
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0414606
|
2-[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-77-amino-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-13-yl]acetic acid
Show/Hide
|
C172H266N52O42S7
|
2
|
| 1 |
IC50 = 5000 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0270495
|
5-chloro-2-fluoro-4-[[(3S)-oxan-3-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C15H17ClFN3O3S2
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0446257
|
4-[3-[3-(dimethylamino)-1,2-benzoxazol-5-yl]morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H20F2N6O5S2
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0515255
|
US9346798, 114
Show/Hide
|
C19H16F3N3O4S2
|
1
|
| 1 |
IC50 = 5060 nM
|
|
|
|
CP0385063
|
US9012443, 11
Show/Hide
|
C20H14F3N3O2S2
|
2
|
| 1 |
IC50 = 5070 nM
|
|
|
| 2 |
IC50 = 5100 nM
|
|
|
|
CP0478772
|
US9346798, 175
Show/Hide
|
C18H13FN4O3S2
|
1
|
| 1 |
IC50 = 5080 nM
|
|
|
|
CP0409170
|
3-[2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxyethyl]-1H-imidazol-2-one
Show/Hide
|
C18H14F2N4O2
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0417310
|
5-chloro-2-fluoro-4-[[1-(pyrrolidin-1-ylmethyl)cyclopropyl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C18H22ClFN4O2S2
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0533488
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-N-(cyclopropylsulfonyl)-5-fluoro-1-methyl-1H-indole-6-carboxamide
Show/Hide
|
C22H23ClFN3O4S
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0086854
|
4-[[(3R,4S)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H19ClF2N4O3S2
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0430198
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-3,5-difluoro-N-methylsulfonylbenzamide
Show/Hide
|
C17H17ClF2N2O4S
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0450032
|
US9346798, 146
Show/Hide
|
C18H16F2N4O4S2
|
1
|
| 1 |
IC50 = 5220 nM
|
|
|
|
CP0527420
|
US8952169, 166
Show/Hide
|
C18H22F3NO4S
|
1
|
| 1 |
IC50 = 5230 nM
|
|
|
|
CP0523358
|
US9346798, 65
Show/Hide
|
C22H21N7O3S2
|
1
|
| 1 |
IC50 = 5280 nM
|
|
|
|
CP0476324
|
3-chloro-5-[4-(5-cyclobutylsulfonyl-1H-1,2,4-triazol-3-yl)-2-methoxyphenyl]-2-(2-methylpropoxy)pyridine
Show/Hide
|
C22H25ClN4O4S
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0383705
|
US9346798, 67
Show/Hide
|
C18H16ClN3O3S2
|
1
|
| 1 |
IC50 = 5330 nM
|
|
|
|
CP0438014
|
N-[3-[[4-(3,4-dihydro-1H-isoquinolin-2-yl)-1,3,5-triazin-2-yl]amino]phenyl]acetamide
Show/Hide
|
C20H20N6O
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0402717
|
US9346798, 23
Show/Hide
|
C21H15F3N6O3S2
|
1
|
| 1 |
IC50 = 5410 nM
|
|
|
|
CP0515493
|
US9346798, 59
Show/Hide
|
C21H23N5O3S2
|
1
|
| 1 |
IC50 = 5570 nM
|
|
|
|
CP0418360
|
US9346798, 150
Show/Hide
|
C18H16FN3O4S2
|
2
|
| 1 |
IC50 = 5580 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0419913
|
US9346798, 178
Show/Hide
|
C18H16ClN3O3S2
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0427633
|
4-[3-(3,5-dichlorophenyl)morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C18H14Cl2F2N4O4S2
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0417292
|
US9051311, 5
Show/Hide
|
C28H30F3N5O4S2
|
1
|
| 1 |
IC50 = 5630 nM
|
|
|
|
CP0479357
|
US9346798, 179
Show/Hide
|
C18H15F2N3O4S2
|
1
|
| 1 |
IC50 = 5640 nM
|
|
|
|
CP0497891
|
US9346798, 80
Show/Hide
|
C18H16FN3O3S2
|
1
|
| 1 |
IC50 = 5640 nM
|
|
|
|
CP0455403
|
3-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-ethylsulfonyl-1-methylindole-6-carboxamide
Show/Hide
|
C21H24ClN3O4S
|
2
|
| 1 |
IC50 = 5673 nM
|
|
|
| 2 |
IC50 = 5700 nM
|
|
|
|
CP0564237
|
5-chloro-2-fluoro-4-[[(2S,8R)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H19ClF2N4O2S2
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
|
CP0407368
|
US9346798, 123
Show/Hide
|
C19H15F4N3O4S2
|
1
|
| 1 |
IC50 = 5810 nM
|
|
|
|
CP0516841
|
US9012443, 47
Show/Hide
|
C24H17F3N4O2S2
|
1
|
| 1 |
IC50 = 5820 nM
|
|
|
|
CP0056400
|
2,5-difluoro-4-[[(3R,4R)-3-(4-fluorophenyl)piperidin-4-yl]methoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H19F3N4O3S2
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0482268
|
3-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-cyclopropylsulfonyl-1-methylindazole-6-carboxamide
Show/Hide
|
C21H23ClN4O4S
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0572387
|
US9012443, 34
Show/Hide
|
C18H12ClN3O2S2
|
1
|
| 1 |
IC50 = 5960 nM
|
|
|
|
CP0218598
|
5-chloro-4-[2-(1,1-dioxothian-4-yl)ethylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H19ClFN3O4S3
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0123797
|
4-[(2R,3R)-3-(3,5-dichlorophenyl)-6,6-dimethylmorpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C20H18Cl2F2N4O4S2
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1
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| 1 |
IC50 = 6000 nM
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CP0430200
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4-(5-chloro-6-(3,5- dichlorophenoxy)-3-pyridinyl)- 3-methoxy-N- (methylsulfonyl)benzamide
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C20H15Cl3N2O5S
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1
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| 1 |
IC50 = 6000 nM
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CP0470256
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US9346798, 76
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C18H14N4O3S2
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1
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| 1 |
IC50 = 6030 nM
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CP0450591
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US9346798, 74
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C17H13Cl2N3O3S2
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1
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| 1 |
IC50 = 6080 nM
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CP0326742
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5-chloro-4-(1,4-dioxaspiro[4.5]decan-7-ylmethylamino)-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C18H21ClFN3O4S2
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1
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| 1 |
IC50 = 6100 nM
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CP0478281
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US9346798, 210
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C20H20ClN3O5S2
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1
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| 1 |
IC50 = 6110 nM
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CP0465560
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US9346798, 130
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C16H13ClN4O3S2
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1
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| 1 |
IC50 = 6200 nM
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CP0422366
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US9346798, 58
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C18H14N4O3S2
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1
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| 1 |
IC50 = 6300 nM
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CP0455563
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3-(5-Chloro-6-isobutoxypyridin-3-yl)-N?N,N-dimethylsulfamoyl)-1-methyl-1H-indole-6-carboxamide
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C21H25ClN4O4S
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1
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| 1 |
IC50 = 6300 nM
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CP0368163
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5-chloro-2-fluoro-4-[[(3R)-oxan-3-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C15H17ClFN3O3S2
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1
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| 1 |
IC50 = 6400 nM
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CP0541394
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5-chloro-4-[(1,1-dioxothian-4-yl)amino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C14H15ClFN3O4S3
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1
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| 1 |
IC50 = 6400 nM
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CP0533513
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N-cyclopropylsulfonyl-5-fluoro-1-methyl-3-[4-(trifluoromethyl)phenyl]indazole-6-carboxamide
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C19H15F4N3O3S
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1
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| 1 |
IC50 = 6400 nM
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CP0533983
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US9546164, 253
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C24H25Cl2FN2O5S
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1
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| 1 |
IC50 = 6400 nM
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CP0414202
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US9346798, 171
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C17H13Cl2N3O3S2
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1
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| 1 |
IC50 = 6440 nM
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CP0859675
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(R)-N-benzyl-2-(4-cyanophenyl)-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)acetamide
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C27H24F2N4O2
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1
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| 1 |
IC50 = 6500 nM
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CP0392346
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3-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindazole-6-carboxamide
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C19H21ClN4O4S
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2
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| 1 |
IC50 = 6500 nM
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| 2 |
IC50 = 6508 nM
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CP0419841
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US9346798, 125
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C18H13ClF3N3O3S2
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1
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| 1 |
IC50 = 6550 nM
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CP0512099
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US9012443, 523
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C25H17ClFN5O3S
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1
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| 1 |
IC50 = 6590 nM
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CP0409370
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US9346798, 140
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C19H16F3N3O4S2
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1
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| 1 |
IC50 = 6600 nM
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CP0445933
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(4S)-4-amino-5-[[(2S)-1-[[(1R,4S,7S,13S,16R,21R,24S,27S,30S,33S,36S,39S,42R,45S,48S,51S,54S,57S,60R,65R,68S,71S,74S)-65-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-27,74-bis(4-aminobutyl)-24-(3-amino-3-oxopropyl)-68-[(5-bromo-1H-indol-3-yl)methyl]-33-butyl-4,54-bis(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-45-(carboxymethyl)-39-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-30,36-bis(1H-indol-3-ylmethyl)-51,57-dimethyl-7,71-bis(2-methylpropyl)-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,67,70,73,76,81-tricosaoxo-18,19,62,63,78,79-hexathia-2,5,8,11,14,23,26,29,32,35,38,41,44,47,50,53,56,59,66,69,72,75,82-tricosazatricyclo[40.34.4.216,60]dooctacontan-21-yl]amino]-1-oxopent-4-yn-2-yl]amino]-5-oxopentanoic acid
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C155H236BrN47O41S6
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1
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| 1 |
IC50 = 6640 nM
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CP0409424
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US9346798, 95
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C20H15F3N4O3S2
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1
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| 1 |
IC50 = 6670 nM
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CP0385814
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US9051311, 32
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C24H22F4N4O2S2
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1
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| 1 |
IC50 = 6680 nM
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CP0527284
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US9012443, 10
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C21H16F3N3O3S2
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1
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| 1 |
IC50 = 6680 nM
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CP0413548
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US9346798, 57
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C17H13N5O3S2
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1
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| 1 |
IC50 = 6700 nM
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CP0946933
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4-(((4-((Benzyloxy)imino)cyclohexyl)methyl)amino)-5-chloro-2-fluoro-N-(thiazol-2-yl)benzenesulfonamide
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C23H24ClFN4O3S2
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1
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| 1 |
IC50 = 6700 nM
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CP0887463
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(R)-N-(2-Cyclopropyl-2,2-difluoroethyl)-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)-2-phenylacetamide
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C24H25F4N3O2
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1
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| 1 |
IC50 = 6700 nM
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CP0397268
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N-[2-methyl-3-[[4-[4-[[4-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
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C25H27F3N6O2
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1
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| 1 |
IC50 = 6800 nM
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CP0481500
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N-[2-pyridazin-3-yl-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
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C24H14F6N4O
|
1
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| 1 |
IC50 = 6800 nM
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CP0427953
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benzyl 7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carboxylate
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C24H25N3O3
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1
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| 1 |
IC50 = 6882 nM
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CP0421283
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4-(5-Chloro-6-((1-Methylcyclopropyl)Methoxy)Pyridin-3-yl)-2-Fluoro-5-Methoxy-N-(Methylsulfonyl)Benzamide
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C20H14ClF3N2O5S
|
4
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| 1 |
IC50 = 6900 nM
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|
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| 2 |
IC50 = 11400 nM
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| 3 |
IC50 = 11900 nM
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| 4 |
IC50 = 13600 nM
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CP0555496
|
US9346798, 180
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C17H13Cl2N3O3S2
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1
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| 1 |
IC50 = 6940 nM
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CP0452848
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(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-(4-methylphenyl)methanone
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C24H25N3O2
|
1
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| 1 |
IC50 = 6943 nM
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CP0534976
|
US9546164, 139
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C24H27Cl2FN2O4S
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1
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| 1 |
IC50 = 7000 nM
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CP0479363
|
US9346798, 122
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C17H13F3N4O3S2
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1
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| 1 |
IC50 = 7030 nM
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CP0409369
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US9346798, 139
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C19H19N3O5S2
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1
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| 1 |
IC50 = 7040 nM
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CP0427955
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(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)-(3-methylphenyl)methanone
Show/Hide
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C24H25N3O2
|
1
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| 1 |
IC50 = 7172 nM
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CP0519945
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5-chloro-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C16H19ClFN5O2S2
|
1
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| 1 |
IC50 = 7200 nM
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CP0423595
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-5-fluoro-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C20H21ClFN3O4S
|
1
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| 1 |
IC50 = 7200 nM
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CP0419579
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2-methoxy-4-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
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C25H24N4O3
|
1
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| 1 |
IC50 = 7240 nM
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CP0474333
|
US9051311, 48
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C24H21F3N6O2S
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1
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| 1 |
IC50 = 7260 nM
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CP0476326
|
3-[4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-2,5-difluorophenyl]-N-cyclopropyl-1H-1,2,4-triazole-5-sulfonamide
Show/Hide
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C20H20ClF2N5O3S
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1
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| 1 |
IC50 = 7300 nM
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CP0531104
|
US9346798, 116
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C19H16N4O3S2
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1
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| 1 |
IC50 = 7360 nM
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CP0516676
|
US9346798, 75
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C18H17N3O3S2
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1
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| 1 |
IC50 = 7370 nM
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CP0409371
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US9346798, 145
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C18H15F3N4O4S2
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1
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| 1 |
IC50 = 7380 nM
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CP0531783
|
US9012443, 270
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C19H13ClF2N4O3S2
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1
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| 1 |
IC50 = 7440 nM
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CP0397815
|
US8952169, 280
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C23H31N3O4S
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1
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| 1 |
IC50 = 7500 nM
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CP0423578
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1-Methyl-3-(4-(trifluoromethyl)phenyl)-N-((trifluoromethyl)sulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C18H12F6N2O3S
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1
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| 1 |
IC50 = 7500 nM
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CP0419536
|
US9346798, 189
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C19H16N4O4S2
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1
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| 1 |
IC50 = 7590 nM
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CP0400086
|
(2-bromophenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
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C23H22BrN3O2
|
1
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| 1 |
IC50 = 7601 nM
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CP0491637
|
US9346798, 185
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C18H14F3N3O4S2
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1
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| 1 |
IC50 = 7620 nM
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CP0375395
|
US9079902, 30
Show/Hide
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C18H12FN5O2S2
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1
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| 1 |
IC50 = 7630 nM
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CP0226080
|
5-chloro-2-fluoro-4-(oxan-3-ylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C14H15ClFN3O3S2
|
1
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| 1 |
IC50 = 7700 nM
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CP0491617
|
US9346798, 186
Show/Hide
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C18H16ClN3O4S2
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1
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| 1 |
IC50 = 7720 nM
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CP0450593
|
US9346798, 115
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C19H16N4O3S2
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1
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| 1 |
IC50 = 7730 nM
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CP0564363
|
US9012443, 39
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C19H11ClF3N3O2S2
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1
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| 1 |
IC50 = 7770 nM
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CP0407455
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-60-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-16-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
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C185H276N52O44S7
|
2
|
| 1 |
IC50 = 7800 nM
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| 2 |
IC50 > 5000 nM
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CP0413966
|
US8952169, 135
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C19H24ClFN2O4S
|
1
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| 1 |
IC50 = 7820 nM
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CP0859593
|
(R)-2-(4-(3,5-Difluorobenzoyl)piperazin-1-yl)-2-phenyl-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)acetamide
Show/Hide
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C26H23F5N4O2
|
1
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| 1 |
IC50 = 7900 nM
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CP0555618
|
US9346798, 47
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C19H14BrF3N4O3S
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1
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| 1 |
IC50 = 7930 nM
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CP0010657
|
CAS_99200-09-6
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C22H25F2NO4
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1
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| 1 |
IC50 = 7943.28 nM
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CP0555332
|
(4-methoxyphenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
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C24H25N3O3
|
1
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| 1 |
IC50 = 8033 nM
|
|
|
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CP0512963
|
US9452986, 29
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C20H16F3N3O4S
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1
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| 1 |
IC50 = 8080 nM
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CP0419580
|
(3,5-dimethylphenyl)-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methanone
Show/Hide
|
C25H27N3O2
|
1
|
| 1 |
IC50 = 8092 nM
|
|
|
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CP0410383
|
4-(8-chlorospiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
Show/Hide
|
C23H19ClN4O
|
1
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| 1 |
IC50 = 8144 nM
|
|
|
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CP0483036
|
US9346798, 14
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C22H23ClF3N5O3S
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1
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| 1 |
IC50 = 8250 nM
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CP0427951
|
4-(7-chlorospiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
Show/Hide
|
C23H19ClN4O
|
1
|
| 1 |
IC50 = 8289 nM
|
|
|
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CP0484761
|
N-(cyclopropylsulfonyl)-1-methyl-3-(4-(trifluoromethyl)phenyl)-1H-indole-6-carboxamide
Show/Hide
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C20H17F3N2O3S
|
1
|
| 1 |
IC50 = 8400 nM
|
|
|
|
CP0443401
|
US9346798, 101
Show/Hide
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C21H17F3N4O3S2
|
1
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| 1 |
IC50 = 8500 nM
|
|
|
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CP0546254
|
US9079902, 25
Show/Hide
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C20H14F3N7O2S2
|
1
|
| 1 |
IC50 = 8550 nM
|
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|
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CP0451290
|
3-(2-Chloro-4-(trifluoromethyl)phenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
|
C18H14ClF3N2O3S
|
1
|
| 1 |
IC50 = 8600 nM
|
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CP0495245
|
1-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]oxy-N-methylsulfonylisoquinoline-6-carboxamide
Show/Hide
|
C20H20ClN3O5S
|
1
|
| 1 |
IC50 = 8700 nM
|
|
|
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CP0428560
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-36,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C176H271N55O45S7
|
2
|
| 1 |
IC50 = 8800 nM
|
|
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| 2 |
IC50 > 5000 nM
|
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|
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CP0460607
|
4-[5-chloro-6-(3-methylphenyl)sulfanylpyridin-3-yl]-3-methoxy-N-methylsulfonylbenzamide
Show/Hide
|
C21H19ClN2O4S2
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
|
CP0395472
|
2-[(9R)-9-pyridin-2-yl-6-oxaspiro[4.5]decan-9-yl]-N-(thiophen-2-ylmethyl)ethanamine
Show/Hide
|
C21H28N2OS
|
2
|
| 1 |
IC50 = 9000 nM
|
|
|
| 2 |
IC50 = 20000 nM
|
|
|
|
CP0345857
|
6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide
Show/Hide
|
C13H10Cl3N3O
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0883378
|
(R)-N-Benzyl-2-(4-(2-chloro-5-fluoronicotinoyl)piperazin-1-yl)-2-phenylacetamide
Show/Hide
|
C25H24ClFN4O2
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0455753
|
4-(8-bromospiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
Show/Hide
|
C23H19BrN4O
|
1
|
| 1 |
IC50 = 9174 nM
|
|
|
|
CP0523078
|
4-(8-fluorospiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
Show/Hide
|
C23H19FN4O
|
1
|
| 1 |
IC50 = 9291 nM
|
|
|
|
CP0430203
|
4-[5-chloro-6-[(1-methylcyclopropyl)methoxy]pyridin-3-yl]-3-methoxy-N-methylsulfonylbenzamide
Show/Hide
|
C19H21ClN2O5S
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0443396
|
US9346798, 152
Show/Hide
|
C19H13F3N4O3S2
|
1
|
| 1 |
IC50 = 9420 nM
|
|
|
|
CP0946797
|
(R)-2-(4-(3,5-Difluorobenzoyl)piperazin-1-yl)-2-phenyl-N-(4-(trifluoromethyl)phenyl)acetamide
Show/Hide
|
C26H22F5N3O2
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
|
CP0565257
|
3-chloro-4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-methylsulfonylbenzamide
Show/Hide
|
C17H18Cl2N2O4S
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
|
CP0573303
|
US9012443, 33
Show/Hide
|
C19H14ClN3O2S2
|
1
|
| 1 |
IC50 = 9580 nM
|
|
|
|
CP0495510
|
US9346798, 103
Show/Hide
|
C18H17ClN4O4S2
|
1
|
| 1 |
IC50 = 9590 nM
|
|
|
|
CP0865295
|
(R)-2-(4-Cyanophenyl)-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)-N-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acetamide
Show/Hide
|
C27H22F5N5O3
|
1
|
| 1 |
IC50 = 9600 nM
|
|
|
|
CP0392348
|
N-cyclopropylsulfonyl-3-[4-(difluoromethyl)phenyl]-5-fluoro-1-methylindole-6-carboxamide
Show/Hide
|
C20H17F3N2O3S
|
1
|
| 1 |
IC50 = 9666 nM
|
|
|
|
CP0396857
|
3-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
Show/Hide
|
C24H22N4O2
|
1
|
| 1 |
IC50 = 9716 nM
|
|
|
|
CP0527285
|
US9012443, 35
Show/Hide
|
C18H11ClFN3O2S2
|
1
|
| 1 |
IC50 = 9990 nM
|
|
|
|
CP0042916
|
4-[[(3S,4R)-4-(4-chlorophenyl)-1-methylpiperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H21ClF2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0042917
|
4-[[(3R,4S)-4-(3,4-difluorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H18F4N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0052822
|
4-[[(3S,4R)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Show/Hide
|
C20H19ClF2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0052823
|
4-[[(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H21ClF2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0052824
|
4-[[(3S,4R)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H19ClF2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0052833
|
2,5-difluoro-4-[[(3S,4R)-4-phenylpiperidin-3-yl]methoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H20F2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0058131
|
4-[[(3R,4S)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(5-fluoropyrimidin-2-yl)benzenesulfonamide
Show/Hide
|
C22H20ClF3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0086715
|
2,5-difluoro-4-[[3-fluoro-4-(4-fluorophenyl)piperidin-3-yl]methoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H18F4N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0086852
|
4-[[(3S,4R)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-pyrimidin-2-ylbenzenesulfonamide
Show/Hide
|
C22H21ClF2N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0123249
|
4-[[(3R,4S)-4-(4-chloro-3-fluorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H18ClF3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0123263
|
2,5-difluoro-4-[[(3R,4S)-4-(4-methylphenyl)piperidin-3-yl]methoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H22F2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0123269
|
4-[[(3S,4R)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-pyrimidin-4-ylbenzenesulfonamide
Show/Hide
|
C22H21ClF2N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0123272
|
4-[[(3S,4R)-4-(4-chlorophenyl)-1-(2-fluoroethyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H22ClF3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0155823
|
4-[[(3S,4R)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamide
Show/Hide
|
C23H21ClF3N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0155824
|
2,5-difluoro-4-[[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H19F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0155825
|
4-[[(3S,4R)-4-(4-chlorophenyl)piperidin-3-yl]methoxy]-2,5-difluoro-N-(5-fluoropyrimidin-2-yl)benzenesulfonamide
Show/Hide
|
C22H20ClF3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0234542
|
2,5-difluoro-4-[[(3S,4R)-4-(4-fluorophenyl)-6-oxopiperidin-3-yl]methoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H17F3N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0375685
|
US9051311, 11
Show/Hide
|
C17H14Cl2N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0380472
|
US9051311, 35
Show/Hide
|
C24H23F3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0380520
|
US9051311, 51
Show/Hide
|
C20H16ClN5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0382528
|
US9051311, 50
Show/Hide
|
C18H16N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384847
|
US9051311, 31
Show/Hide
|
C21H17F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384858
|
US9051311, 12
Show/Hide
|
C20H21N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384859
|
US9051311, 22
Show/Hide
|
C22H17F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385021
|
US9051311, 13
Show/Hide
|
C24H24F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385067
|
US9051311, 61
Show/Hide
|
C24H20F2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385438
|
US9051311, 34
Show/Hide
|
C24H24F4N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385497
|
US9051311, 28
Show/Hide
|
C18H17FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385851
|
US9051311, 47
Show/Hide
|
C20H19F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0388916
|
US9051311, 54
Show/Hide
|
C19H17F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389355
|
US9051311, 10
Show/Hide
|
C17H14ClFN4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400934
|
US9051311, 30
Show/Hide
|
C22H22F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0402979
|
US9051311, 17
Show/Hide
|
C23H19F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0402999
|
US9051311, 43
Show/Hide
|
C19H17F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403005
|
US9051311, 6
Show/Hide
|
C23H22F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407208
|
US9051311, 26
Show/Hide
|
C19H20N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409740
|
US9051311, 33
Show/Hide
|
C22H20F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0411061
|
US9051311, 39
Show/Hide
|
C25H24F4N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0411378
|
US9051311, 45
Show/Hide
|
C18H16F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0411404
|
US9051311, 55
Show/Hide
|
C20H16BrF3N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413786
|
US9051311, 3
Show/Hide
|
C18H14BrF3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0415637
|
US9051311, 8
Show/Hide
|
C18H14ClF3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0415896
|
US9051311, 27
Show/Hide
|
C19H20N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0417693
|
US9051311, 24
Show/Hide
|
C20H17N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420221
|
US9051311, 29
Show/Hide
|
C18H17FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420636
|
US9051311, 53
Show/Hide
|
C24H23ClF2N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0422495
|
US9051311, 18
Show/Hide
|
C23H21F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0429201
|
US9051311, 9
Show/Hide
|
C17H15ClN4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0429697
|
US9051311, 1
Show/Hide
|
C23H18F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0429727
|
US9051311, 37
Show/Hide
|
C22H17F4N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0434790
|
US9051311, 20
Show/Hide
|
C24H20F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0444261
|
US9051311, 38
Show/Hide
|
C25H24F4N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0456756
|
US9051311, 49
Show/Hide
|
C17H17N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0462745
|
US9051311, 25
Show/Hide
|
C19H20N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0467507
|
US9051311, 40
Show/Hide
|
C24H25F4N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0468178
|
US9051311, 16
Show/Hide
|
C21H17F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0469283
|
US9051311, 36
Show/Hide
|
C30H32F3N5O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470121
|
US9051311, 7
Show/Hide
|
C18H14F4N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470195
|
US9051311, 14
Show/Hide
|
C24H24F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472510
|
US9051311, 57
Show/Hide
|
C25H29N5O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0475535
|
US9051311, 19
Show/Hide
|
C24H20F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0486555
|
US9051311, 44
Show/Hide
|
C21H22N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0491032
|
US9051311, 56
Show/Hide
|
C21H27N5O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519853
|
US9051311, 59
Show/Hide
|
C18H15F4N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519882
|
US9051311, 15
Show/Hide
|
C22H19F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531141
|
US9051311, 2
Show/Hide
|
C23H20F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0539646
|
US9051311, 46
Show/Hide
|
C20H21N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0542626
|
US9051311, 23
Show/Hide
|
C21H18N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0544712
|
US9051311, 52
Show/Hide
|
C25H24F3N5O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0546758
|
US9051311, 42
Show/Hide
|
C23H19F4N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0547637
|
US9051311, 58
Show/Hide
|
C18H16F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0548849
|
US9051311, 41
Show/Hide
|
C23H19F4N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0468187
|
US9051311, 4
Show/Hide
|
C23H21BrF3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0375724
|
US9079902, 62
Show/Hide
|
C19H14ClN7O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0375996
|
US9079902, 22
Show/Hide
|
C23H20F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0380195
|
US9079902, 26
Show/Hide
|
C21H16F3N7O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0380502
|
US9079902, 13
Show/Hide
|
C22H17F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385162
|
US9079902, 34
Show/Hide
|
C18H13N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385537
|
US9079902, 23
Show/Hide
|
C18H12ClF3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389350
|
US9079902, 31
Show/Hide
|
C18H12FN5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389375
|
US9079902, 39
Show/Hide
|
C18H16N4O4S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0395026
|
US9079902, 63
Show/Hide
|
C20H14F3N7O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0397126
|
US9079902, 66
Show/Hide
|
C24H21F3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401171
|
US9079902, 43
Show/Hide
|
C18H12BrF3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401294
|
US9079902, 3
Show/Hide
|
C24H21F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403414
|
US9079902, 33
Show/Hide
|
C18H13F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407609
|
US9079902, 47
Show/Hide
|
C19H19N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409891
|
US9079902, 56
Show/Hide
|
C17H14FN5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0411542
|
US9079902, 28
Show/Hide
|
C18H15FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0411916
|
US9079902, 10
Show/Hide
|
C17H12F2N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413905
|
US9079902, 41
Show/Hide
|
C18H15ClN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413989
|
US9079902, 18
Show/Hide
|
C23H16F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0416408
|
US9079902, 57
Show/Hide
|
C18H13F3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0417853
|
US9079902, 9
Show/Hide
|
C16H13N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420191
|
US9079902, 38
Show/Hide
|
C20H15N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0425426
|
US9079902, 53
Show/Hide
|
C20H19N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0431793
|
US9079902, 20
Show/Hide
|
C25H19F6N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435052
|
US9079902, 2
Show/Hide
|
C21H17ClN6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435104
|
US9079902, 5
Show/Hide
|
C21H15F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435224
|
US9079902, 16
Show/Hide
|
C19H12F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0441443
|
US9079902, 48
Show/Hide
|
C18H13F3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0458972
|
US9079902, 46
Show/Hide
|
C19H15N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459014
|
US9079902, 55
Show/Hide
|
C17H16N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0464078
|
US9079902, 37
Show/Hide
|
C21H16N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0467510
|
US9079902, 17
Show/Hide
|
C18H12BrF3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470118
|
US9079902, 60
Show/Hide
|
C19H15N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470119
|
US9079902, 32
Show/Hide
|
C18H13F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470349
|
US9079902, 36
Show/Hide
|
C19H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470361
|
US9079902, 21
Show/Hide
|
C21H15F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472512
|
US9079902, 49
Show/Hide
|
C19H15F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472581
|
US9079902, 44
Show/Hide
|
C18H13F3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0474332
|
US9079902, 14
Show/Hide
|
C19H15N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0474738
|
US9079902, 65
Show/Hide
|
C24H21F3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0474781
|
US9079902, 51
Show/Hide
|
C16H12ClN5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0481987
|
US9079902, 4
Show/Hide
|
C23H17F3N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0486537
|
US9079902, 24
Show/Hide
|
C18H12ClF3N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0487169
|
US9079902, 59
Show/Hide
|
C19H14N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0487312
|
US9079902, 8
Show/Hide
|
C22H17F3N6O2S2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0491023
|
US9079902, 19
Show/Hide
|
C24H20F3N7O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0520357
|
US9079902, 6
Show/Hide
|
C23H17F3N6O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0525149
|
US9079902, 40
Show/Hide
|
C22H18N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0527422
|
US9079902, 58
Show/Hide
|
C18H13F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531140
|
US9079902, 11
Show/Hide
|
C23H18F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0538182
|
US9079902, 35
Show/Hide
|
C17H14N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0540802
|
US9079902, 42
Show/Hide
|
C16H15N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0541439
|
US9079902, 52
Show/Hide
|
C15H14N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0545746
|
US9079902, 7
Show/Hide
|
C22H17F3N6O4S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0546266
|
US9079902, 29
Show/Hide
|
C19H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0546279
|
US9079902, 45
Show/Hide
|
C17H16N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0546554
|
US9079902, 1
Show/Hide
|
C20H15ClN6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0546674
|
US9079902, 15
Show/Hide
|
C23H16F3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0547163
|
US9079902, 50
Show/Hide
|
C22H16BrF3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0547714
|
US9079902, 61
Show/Hide
|
C17H15N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0548063
|
US9079902, 27
Show/Hide
|
C22H16F3N7O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0550835
|
US9079902, 12
Show/Hide
|
C24H19F3N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385035
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19,36-tris(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C174H264N52O47S7
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 = 37900 nM
|
|
|
|
CP0385036
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-69-[3-[(N,N'-dimethylcarbamimidoyl)amino]propyl]-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C178H275N53O45S7
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0399105
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-33-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C178H272N52O45S7
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0399106
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-4,16,60-tris(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C174H266N54O46S7
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0407457
|
(3S)-3-amino-4-[[(1R,4S,7S,10S,13S,19S,22R,27R,30S,36S,39S,42S,45S,48R,51S,54S,57S,60S,63S,66S,69R,74R,77S,80S,83S,86S,89S,92S)-74-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-45,66,80-tris(4-aminobutyl)-10,60-bis(2-amino-2-oxoethyl)-36-benzyl-51-[(2S)-butan-2-yl]-19,42,89-tris(3-carbamimidamidopropyl)-54-(2-carboxyethyl)-57,63-bis(carboxymethyl)-86-[(1R)-1-hydroxyethyl]-92-(hydroxymethyl)-83-(1H-imidazol-5-ylmethyl)-77-(1H-indol-3-ylmethyl)-7,30-bis(2-methylpropyl)-39-(2-methylsulfanylethyl)-3,6,9,12,18,21,28,31,34,37,40,43,46,49,52,55,58,61,64,67,76,79,82,85,88,91,94,99-octacosaoxo-4-propan-2-yl-24,25,71,72,96,97-hexathia-a,2,5,8,11,17,20,29,32,35,38,41,44,47,50,53,56,59,62,65,68,75,78,81,84,87,90,93-octacosazatetracyclo[46.46.4.222,69.013,17]hectan-27-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C176H271N53O47S7
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0407479
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-4,13,19-tris(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C174H265N53O47S7
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
|
CP0414640
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-69-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C175H266N50O47S7
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
IC50 > 5000 nM
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CP0420127
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(3S)-3-acetamido-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H273N53O46S7
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
IC50 > 5000 nM
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CP0424606
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,66S,69R,74R,77S,83S,86S,89S,92S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,63,92-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-83-benzyl-4-[(2S)-butan-2-yl]-45,66,89-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,77-bis(2-methylpropyl)-86-(2-methylsulfanylethyl)-a,2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,65,68,75,78,81,84,87,90,93-octacosaoxo-54-propan-2-yl-27,28,71,72,96,97-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,64,67,76,79,82,85,88,91,94,99-octacosazatetracyclo[49.43.4.225,69.06,10]hectan-74-yl]amino]-4-oxobutanoic acid
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C177H276N54O45S7
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
IC50 > 5000 nM
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CP0428557
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-4-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H267N53O47S7
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2
|
| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 5000 nM
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CP0434636
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-69-[4-(dimethylamino)butyl]-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H275N51O45S7
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2
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| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 5000 nM
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CP0443464
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(3S)-3-amino-4-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
Show/Hide
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C176H270N52O46S7
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2
|
| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 5000 nM
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|
|
CP0447932
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-36-(3-amino-3-oxopropyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
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C175H267N53O46S7
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2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 = 22700 nM
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CP0447940
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-69-(1H-indol-2-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
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C181H269N51O45S7
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2
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| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 5000 nM
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CP0447945
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-69-[3-(carbamoylamino)propyl]-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
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C176H270N52O46S7
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2
|
| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 5000 nM
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CP0851084
|
(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,83S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-83-methyl-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C177H273N53O45S7
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2
|
| 1 |
IC50 > 10000 nM
|
|
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| 2 |
IC50 > 5000 nM
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CP0110199
|
4-[2-(2-amino-3H-benzimidazol-5-yl)-4-chlorophenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C21H13ClF2N6O3S2
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0133044
|
4-[2-(3H-benzimidazol-5-yl)-4-chlorophenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C21H12ClF2N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0191931
|
4-[2-(3-amino-1H-indazol-5-yl)-4-chlorophenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C21H13ClF2N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0204855
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4-(4-chloro-2-quinoxalin-6-ylphenoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C22H12ClF2N5O3S2
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1
|
| 1 |
IC50 > 10000 nM
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|
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CP0234231
|
4-(4-chloro-2-imidazo[1,2-a]pyridin-5-ylphenoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C21H12ClF2N5O3S2
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0234233
|
4-[4-chloro-2-(5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-3-yl)phenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C20H15ClF2N6O3S2
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0445157
|
4-[4-chloro-2-(2-oxo-1,3-dihydrobenzimidazol-5-yl)phenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C21H12ClF2N5O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
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|
CP0380324
|
2-[(1-methyl-1,2,4-triazol-3-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C17H13F3N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0398932
|
2-[(3-methyl-1,2-oxazol-5-yl)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C18H13F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0425500
|
US9212182, 924
Show/Hide
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C27H20ClFN4O5S
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0483990
|
US9212182, 698
Show/Hide
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C27H22FN3O6S
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0483991
|
US9212182, 628
Show/Hide
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C27H20ClFN4O5S
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0483992
|
US9212182, 685
Show/Hide
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C27H20ClFN4O5S
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0539145
|
US9212182, 1075
Show/Hide
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C25H18ClFN4O4S2
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0555567
|
US9212182, 581
Show/Hide
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C25H19FN4O6S
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0379742
|
US9346798, 219
Show/Hide
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C20H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0383586
|
US9346798, 166
Show/Hide
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C20H16N4O3S2
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0383587
|
US9346798, 187
Show/Hide
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C18H13FN4O3S2
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0383590
|
US9346798, 226
Show/Hide
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C19H16N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0383592
|
US9346798, 13
Show/Hide
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C18H13ClF3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0397878
|
US9346798, 222
Show/Hide
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C19H17N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0398958
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US9346798, 142
Show/Hide
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C18H13ClN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0402673
|
US9346798, 62
Show/Hide
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C25H23F3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0402675
|
US9346798, 73
Show/Hide
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C21H18N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406894
|
US9346798, 15
Show/Hide
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C19H16ClF3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406906
|
US9346798, 30
Show/Hide
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C16H14N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406907
|
US9346798, 36
Show/Hide
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C20H16N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406909
|
US9346798, 71
Show/Hide
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C18H14N4O3S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406910
|
US9346798, 105
Show/Hide
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C19H18ClN3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406911
|
US9346798, 143
Show/Hide
|
C17H17N5O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406912
|
US9346798, 148
Show/Hide
|
C21H19N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407364
|
US9346798, 106
Show/Hide
|
C20H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407365
|
US9346798, 109
Show/Hide
|
C18H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407366
|
US9346798, 112
Show/Hide
|
C20H21N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407367
|
US9346798, 118
Show/Hide
|
C19H16N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409372
|
US9346798, 167
Show/Hide
|
C19H13F3N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412300
|
US9346798, 18
Show/Hide
|
C17H13ClF3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412302
|
US9346798, 19
Show/Hide
|
C18H15ClF3N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412333
|
US9346798, 1
Show/Hide
|
C17H12BrF3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412523
|
US9346798, 191
Show/Hide
|
C18H13ClN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412632
|
US9346798, 55
Show/Hide
|
C18H13ClF3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412634
|
US9346798, 91
Show/Hide
|
C19H13F3N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412635
|
US9346798, 144
Show/Hide
|
C18H18N4O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412636
|
US9346798, 154
Show/Hide
|
C20H17N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412666
|
US9346798, 33
Show/Hide
|
C19H15N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412674
|
US9346798, 197
Show/Hide
|
C18H14N4O7S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413516
|
US9346798, 82
Show/Hide
|
C18H16FN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413518
|
US9346798, 88
Show/Hide
|
C24H22F3N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413550
|
US9346798, 104
Show/Hide
|
C19H18ClN3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413552
|
US9346798, 137
Show/Hide
|
C18H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413562
|
US9346798, 40
Show/Hide
|
C17H14ClN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414470
|
US9346798, 99
Show/Hide
|
C18H13ClF3N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414472
|
US9346798, 136
Show/Hide
|
C16H12F2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414653
|
US9346798, 133
Show/Hide
|
C18H18N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414654
|
US9346798, 153
Show/Hide
|
C19H16N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418144
|
US9346798, 28
Show/Hide
|
C17H12ClF3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418167
|
US9346798, 42
Show/Hide
|
C22H18F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418352
|
US9346798, 155
Show/Hide
|
C17H13ClFN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419500
|
US9346798, 39
Show/Hide
|
C19H20N4O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419523
|
US9346798, 117
Show/Hide
|
C17H13N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419526
|
US9346798, 151
Show/Hide
|
C18H16FN3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419529
|
US9346798, 157
Show/Hide
|
C18H14F3N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419531
|
US9346798, 170
Show/Hide
|
C17H13ClFN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419538
|
US9346798, 214
Show/Hide
|
C18H15F3N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419551
|
US9346798, 131
Show/Hide
|
C17H16N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419553
|
US9346798, 164
Show/Hide
|
C18H13FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419554
|
US9346798, 169
Show/Hide
|
C18H16ClN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419555
|
US9346798, 173
Show/Hide
|
C18H14F3N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419556
|
US9346798, 181
Show/Hide
|
C19H16N4O4S2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 = 14000 nM
|
|
|
|
CP0419842
|
US9346798, 132
Show/Hide
|
C18H18N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419843
|
US9346798, 176
Show/Hide
|
C17H13F2N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419915
|
US9346798, 221
Show/Hide
|
C22H20N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0441209
|
US9346798, 81
Show/Hide
|
C18H16FN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0442951
|
US9346798, 46
Show/Hide
|
C17H14ClN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0442953
|
US9346798, 70
Show/Hide
|
C18H14N4O3S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0442955
|
US9346798, 79
Show/Hide
|
C18H16FN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0443389
|
US9346798, 158
Show/Hide
|
C17H16N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0447653
|
US9346798, 223
Show/Hide
|
C19H14F3N3O5S2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0449945
|
US9346798, 24
Show/Hide
|
C18H13ClF3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0449950
|
US9346798, 147
Show/Hide
|
C22H18N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450584
|
US9346798, 134
Show/Hide
|
C18H18N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450590
|
US9346798, 72
Show/Hide
|
C18H14N4O3S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450592
|
US9346798, 108
Show/Hide
|
C20H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450594
|
US9346798, 127
Show/Hide
|
C18H13F2N3O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0464860
|
US9346798, 98
Show/Hide
|
C20H15F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0464861
|
US9346798, 110
Show/Hide
|
C17H15FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0464863
|
US9346798, 165
Show/Hide
|
C17H15N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0465559
|
US9346798, 129
Show/Hide
|
C18H13F2N3O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0470229
|
US9346798, 149
Show/Hide
|
C22H23N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0478286
|
US9346798, 2
Show/Hide
|
C17H12ClF3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0478742
|
US9346798, 61
Show/Hide
|
C18H13BrF3N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0479358
|
US9346798, 90
Show/Hide
|
C19H13F3N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0479362
|
US9346798, 120
Show/Hide
|
C19H19N3O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0481552
|
US9346798, 205
Show/Hide
|
C18H17N3O4S2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0482987
|
US9346798, 27
Show/Hide
|
C19H14ClF3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0484003
|
US9346798, 16
Show/Hide
|
C19H14ClF3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485509
|
US9346798, 119
Show/Hide
|
C19H19N3O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0490222
|
US9346798, 121
Show/Hide
|
C16H12Cl2N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0491614
|
US9346798, 168
Show/Hide
|
C21H23N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0491616
|
US9346798, 183
Show/Hide
|
C17H13F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0495509
|
US9346798, 77
Show/Hide
|
C18H17N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0495534
|
US9346798, 34
Show/Hide
|
C23H17F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0497896
|
US9346798, 78
Show/Hide
|
C18H16FN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0506727
|
US9346798, 35
Show/Hide
|
C17H13F3N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0506791
|
US9346798, 107
Show/Hide
|
C20H18N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0512307
|
US9346798, 10
Show/Hide
|
C18H14ClF3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0512330
|
US9346798, 220
Show/Hide
|
C18H17N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0512721
|
US9346798, 11
Show/Hide
|
C18H13ClF3N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0514965
|
US9346798, 48
Show/Hide
|
C22H22F3N5O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0515267
|
US9346798, 177
Show/Hide
|
C18H13FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0516378
|
US9346798, 162
Show/Hide
|
C19H19N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0516675
|
US9346798, 22
Show/Hide
|
C23H22F3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0518150
|
US9346798, 172
Show/Hide
|
C18H15F2N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519221
|
US9346798, 37
Show/Hide
|
C17H16N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519223
|
US9346798, 9
Show/Hide
|
C19H13Cl2F3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519227
|
US9346798, 126
Show/Hide
|
C18H13ClF3N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519228
|
US9346798, 190
Show/Hide
|
C17H16N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519231
|
US9346798, 64
Show/Hide
|
C17H13BrN6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519232
|
US9346798, 66
Show/Hide
|
C20H16N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519922
|
US9346798, 135
Show/Hide
|
C18H15N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0520488
|
US9346798, 60
Show/Hide
|
C20H15BrF3N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0521568
|
US9346798, 8
Show/Hide
|
C18H15ClF3N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0523359
|
US9346798, 85
Show/Hide
|
C23H21F3N4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0524615
|
US9346798, 159
Show/Hide
|
C18H13FN4O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0524616
|
US9346798, 160
Show/Hide
|
C21H19N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0525261
|
US9346798, 83
Show/Hide
|
C17H13F2N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0527357
|
US9346798, 51
Show/Hide
|
C25H24F3N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0527360
|
US9346798, 12
Show/Hide
|
C19H15ClF3N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531096
|
US9346798, 17
Show/Hide
|
C20H14ClF4N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0533752
|
US9346798, 92
Show/Hide
|
C16H11ClN4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0536819
|
US9346798, 228
Show/Hide
|
C17H22N4O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0547686
|
US9346798, 87
Show/Hide
|
C24H22F3N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0069424
|
1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-1,3-oxazol-2-yl-6-isoquinolinesulfonamide
Show/Hide
|
C25H17ClFN3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0081107
|
US9012443, 333
Show/Hide
|
C26H18ClFN4O3S
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 = 20300 nM
|
|
|
|
CP0081111
|
1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-2-pyrimidinyl-6-isoquinolinesulfonamide
Show/Hide
|
C26H18ClFN4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0081155
|
N-3-isoxazolyl-1-(2,3',5'-trifluoro-5-methoxy-4-biphenylyl)-6-isoquinolinesulfonamide
Show/Hide
|
C25H16F3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0081156
|
1-[5-fluoro-2-methoxy-4-(3-methylphenyl)phenyl]-N-(1,2-oxazol-3-yl)isoquinoline-6-sulfonamide
Show/Hide
|
C26H20FN3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0126401
|
1-(4'-chloro-2-fluoro-5-methoxy-3'-methyl-4-biphenylyl)-N-3-isoxazolyl-6-isoquinolinesulfonamide
Show/Hide
|
C26H19ClFN3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0323374
|
4-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-isoxazolyl-2-methyl-3-oxo-2,3-dihydro-7-isoquinolinesulfonamide
Show/Hide
|
C26H19ClFN3O5S
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0323375
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1-(3'-chloro-2-fluoro-5-methoxy-4-biphenylyl)-N-3-isoxazolyl-6-isoquinolinesulfonamide
Show/Hide
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C25H17ClFN3O4S
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0323807
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1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-pyridazinyl-6-isoquinolinesulfonamide
Show/Hide
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C26H18ClFN4O3S
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0365564
|
US9012443, 335
Show/Hide
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C25H17ClFN3O4S
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2
|
| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 30000 nM
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CP0387261
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4-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-isoxazolyl-7-quinazolinesulfonamide
Show/Hide
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C24H16ClFN4O4S
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0408069
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1-(2-fluoro-5-methoxy-4'-(trifluoromethyl)-4-biphenylyl)-N-3-isoxazolyl-6-isoquinolinesulfonamide
Show/Hide
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C26H17F4N3O4S
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0416952
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1-(5-fluoro-4-(5-fluoro-2-methoxy-3-pyridinyl)-2-methoxyphenyl)-N-3-isoxazolyl-6-isoquinolinesulfonamide
Show/Hide
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C25H18F2N4O5S
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0519591
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1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-isoxazolyl-3-methyl-4-oxo-3,4-dihydro-6-phthalazinesulfonamide
Show/Hide
|
C25H18ClFN4O5S
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0539218
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1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-1,2,4-oxadiazol-3-yl-6-isoquinolinesulfonamide
Show/Hide
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C24H16ClFN4O4S
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1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0548795
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1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-4-hydroxy-N-3-isoxazolyl-6-isoquinolinesulfonamide
Show/Hide
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C25H17ClFN3O5S
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0315694
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4-[[(1R,6R)-6-amino-2-(4-fluorophenyl)cyclohex-2-en-1-yl]methoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
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C22H20ClF2N3O3S2
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0566516
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5-chloro-2-fluoro-4-[[5-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-6-yl]methoxy]-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C21H18ClF2N3O3S2
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0095952
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3-cyano-4-[2-(2-methylpyrazol-3-yl)phenoxy]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C20H15N5O3S2
|
2
|
| 1 |
IC50 > 10000 nM
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|
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| 2 |
IC50 > 30000 nM
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|
|
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CP0153087
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4-[4-chloro-2-[2-(1-ethylazetidin-3-yl)pyrazol-3-yl]phenoxy]-2,5-difluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C23H20ClF2N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
|
CP0165599
|
5-chloro-4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-2-fluoro-N-pyrimidin-4-ylbenzenesulfonamide
Show/Hide
|
C20H14Cl2FN5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0169863
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5-chloro-4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-2-fluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamide
Show/Hide
|
C21H14Cl2F2N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0197731
|
4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-cyano-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C20H14ClN5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0247320
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4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C18H12ClN7O3S2
|
1
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| 1 |
IC50 > 10000 nM
|
|
|
|
CP0319124
|
4-[2-(2-aminopyridin-4-yl)-4-chlorophenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H13ClN6O3S2
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1
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| 1 |
IC50 > 10000 nM
|
|
|
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CP0334667
|
5-chloro-2-fluoro-4-[2-(oxolan-3-yl)ethylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C15H17ClFN3O3S2
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1
|
| 1 |
IC50 = 10000 nM
|
|
|
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CP0495068
|
3-chloro-5-[4-[5-(cyclopropylmethylsulfonyl)-1H-1,2,4-triazol-3-yl]-2,5-difluorophenyl]-2-(2-methylpropoxy)pyridine
Show/Hide
|
C21H21ClF2N4O3S
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1
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| 1 |
IC50 = 10000 nM
|
|
|
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CP0369848
|
5-chloro-4-[[(1R,6R)-6-(ethylamino)-2-(4-fluorophenyl)cyclohex-2-en-1-yl]methoxy]-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide;hydrochloride
Show/Hide
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C24H25Cl2F2N3O3S2
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0902832
|
(R)-N-Benzyl-2-(4-(3,5-difluorobenzoyl)piperazin-1-yl)-N-methyl-2-phenylacetamide
Show/Hide
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C27H27F2N3O2
|
1
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| 1 |
IC50 = 10000 nM
|
|
|
|
CP0428561
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,83S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,83,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C180H280N54O45S7
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2
|
| 1 |
IC50 = 10100 nM
|
|
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| 2 |
IC50 > 5000 nM
|
|
|
|
CP0515154
|
US9452986, 508
Show/Hide
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C19H12F5N3O2
|
1
|
| 1 |
IC50 = 10200 nM
|
|
|
|
CP0119710
|
4-[2-(5-amino-1H-pyrazol-4-yl)-4-(trifluoromethyl)phenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C19H12ClF4N5O3S2
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1
|
| 1 |
IC50 = 10549 nM
|
|
|
|
CP0572385
|
US9012443, 4
Show/Hide
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C19H11ClF3N3O3S2
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1
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| 1 |
IC50 = 10900 nM
|
|
|
|
CP0476323
|
4-[(3,4-dichlorophenoxy)methyl]-2,5-difluoro-N-methylsulfonylbenzamide
Show/Hide
|
C15H11Cl2F2NO4S
|
1
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| 1 |
IC50 = 11000 nM
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|
|
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CP0924347
|
(R)-2-(4-(2-Chloro-5-fluoronicotinoyl)piperazin-1-yl)-2-phenyl-N-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acetamide
Show/Hide
|
C25H22ClF4N5O3
|
1
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| 1 |
IC50 = 11000 nM
|
|
|
|
CP0423586
|
N-cyclopropylsulfonyl-5-fluoro-1-methyl-3-[6-(2-methylpropoxy)pyridin-3-yl]indazole-6-carboxamide
Show/Hide
|
C21H23FN4O4S
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
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CP0476224
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-N-(cyclopropylsulfonyl)-1-isobutyl-1H-indole-6-carboxamide
Show/Hide
|
C25H30ClN3O4S
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1
|
| 1 |
IC50 = 11000 nM
|
|
|
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CP0530170
|
4-[5-chloro-6-[(1-methylcyclopropyl)methoxy]pyridin-3-yl]-2-fluoro-5-methoxy-N-methylsulfonylbenzamide
Show/Hide
|
C19H20ClFN2O5S
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0235884
|
3-cyano-4-[2-(5-methyl-1H-pyrazol-4-yl)-4-(trifluoromethyl)phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H13F3N6O3S2
|
1
|
| 1 |
IC50 = 11102 nM
|
|
|
|
CP0412123
|
US9012443, 12
Show/Hide
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C20H14F3N3O3S2
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2
|
| 1 |
IC50 = 11600 nM
|
|
|
| 2 |
IC50 = 12000 nM
|
|
|
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CP0460604
|
4-[5-chloro-6-(5-chloro-2-methoxypyridin-3-yl)oxypyridin-3-yl]-3-methoxy-N-methylsulfonylbenzamide
Show/Hide
|
C20H17Cl2N3O6S
|
1
|
| 1 |
IC50 = 11600 nM
|
|
|
|
CP0189295
|
5-N-[4-(4-chlorophenoxy)phenyl]pyridine-3,5-diamine
Show/Hide
|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 11800 nM
|
|
|
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CP0109894
|
N-[6-amino-5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]-3-methyl-1,2-oxazole-4-carboxamide
Show/Hide
|
C17H13F3N4O3
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0323810
|
1-(2-fluoro-5-methoxy-3'-(trifluoromethyl)-4-biphenylyl)-N-3-isoxazolyl-6-isoquinolinesulfonamide
Show/Hide
|
C26H17F4N3O4S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0430557
|
3-chloro-5-[4-[5-(cyclopropylmethylsulfonyl)-1H-1,2,4-triazol-3-yl]-2,5-difluorophenyl]-2-(2,4-difluorophenoxy)pyridine
Show/Hide
|
C23H15ClF4N4O3S
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1
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| 1 |
IC50 = 12000 nM
|
|
|
|
CP0508327
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-N-(cyclopropylsulfonyl)-1-methyl-1H-indole-6-carboxamide
Show/Hide
|
C22H24ClN3O4S
|
1
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| 1 |
IC50 = 12000 nM
|
|
|
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CP0533512
|
3-[5-chloro-6-(2,2,2-trifluoroethoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindole-6-carboxamide
Show/Hide
|
C18H15ClF3N3O4S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0545736
|
US9012443, 276
Show/Hide
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C20H14F3N3O3S2
|
1
|
| 1 |
IC50 = 12300 nM
|
|
|
|
CP0334666
|
4-[[(3aS,7aR)-2,3,4,5,6,7a-hexahydrofuro[2,3-b]pyran-3a-yl]methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H19ClFN3O4S2
|
1
|
| 1 |
IC50 = 12800 nM
|
|
|
|
CP0414293
|
3-[(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-yl)methyl]benzonitrile
Show/Hide
|
C24H24N4O
|
1
|
| 1 |
IC50 = 12875 nM
|
|
|
|
CP0076327
|
1-(2,6-dimethylphenoxy)-2-propanolamine
Show/Hide
|
C11H17NO
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0447946
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-4-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C183H271N53O45S7
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2
|
| 1 |
IC50 = 13000 nM
|
|
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| 2 |
IC50 > 5000 nM
|
|
|
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CP0863975
|
(R)-1-(5-(4-chlorophenyl)-1H-imidazol-2-yl)-4-methylpentan-2-amine
Show/Hide
|
C15H20ClN3
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0952991
|
(S)-1-(4-(4-chlorophenyl)-1H-imidazol-2-yl)-4-methylpentan-2-amine
Show/Hide
|
C15H20ClN3
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0465220
|
N-[2-pyridin-4-yl-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)pyridin-2-yl]benzamide
Show/Hide
|
C25H15F6N3O
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
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CP0387326
|
3-chloro-5-[4-[5-(cyclopropylmethylsulfonyl)-1H-1,2,4-triazol-3-yl]-2,5-difluorophenyl]-2-[2-(trifluoromethyl)phenoxy]pyridine
Show/Hide
|
C24H16ClF5N4O3S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0401849
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-69-(pyridin-2-ylmethyl)-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C178H267N51O45S7
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2
|
| 1 |
IC50 = 13100 nM
|
|
|
| 2 |
IC50 > 5000 nM
|
|
|
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CP0483457
|
4-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carbonyl)benzonitrile
Show/Hide
|
C24H22N4O2
|
1
|
| 1 |
IC50 = 13770 nM
|
|
|
|
CP0849637
|
(R)-2-(4-(3-Cyano-5-fluorobenzoyl)piperazin-1-yl)-N-(2-cyclopropyl-2,2-difluoroethyl)-2-phenylacetamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0484822
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-N-(isopropylsulfonyl)-1-methyl-1H-indole-6-carboxamide
Show/Hide
|
C22H26ClN3O4S
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0490518
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxazol-2-ylmethyl)imidazolidin-2-one
Show/Hide
|
C20H16FN5O2
|
1
|
| 1 |
IC50 = 14200 nM
|
|
|
|
CP0557026
|
US9012443, 37
Show/Hide
|
C19H12F3N3O2S2
|
1
|
| 1 |
IC50 = 14400 nM
|
|
|
|
CP0463605
|
1-[4-chloro-3-(trifluoromethyl)phenoxy]-N-methylsulfonylisoquinoline-6-carboxamide
Show/Hide
|
C18H12ClF3N2O4S
|
1
|
| 1 |
IC50 = 14400 nM
|
|
|
|
CP0051988
|
4-[2-(5-amino-1H-pyrazol-4-yl)-4-(trifluoromethyl)phenoxy]-5-chloro-2-fluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Show/Hide
|
C18H11ClF4N6O3S2
|
1
|
| 1 |
IC50 = 14413 nM
|
|
|
|
CP0030226
|
4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide
Show/Hide
|
C23H29ClFN3O4
|
1
|
| 1 |
IC50 = 14700 nM
|
|
|
|
CP0519538
|
5-chloro-2-fluoro-4-[(3-methyloxetan-3-yl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C14H15ClFN3O3S2
|
1
|
| 1 |
IC50 = 14800 nM
|
|
|
|
CP0420263
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(4-methyl-2-oxopentyl)imidazolidin-2-one
Show/Hide
|
C22H23FN4O2
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0319111
|
4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C18H13ClFN5O3S2
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1
|
| 1 |
IC50 = 15060 nM
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|
|
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CP0557025
|
US9012443, 36
Show/Hide
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C19H11F4N3O2S2
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1
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| 1 |
IC50 = 15100 nM
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|
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CP0392347
|
3-[5-chloro-6-(cyclopropylmethoxy)pyridin-3-yl]-N-cyclopropylsulfonyl-1-methylindole-6-carboxamide
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C22H22ClN3O4S
|
1
|
| 1 |
IC50 = 15105 nM
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|
|
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CP0468437
|
US8952169, 281
Show/Hide
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C23H32N2O5S
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1
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| 1 |
IC50 = 15300 nM
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|
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CP0008168
|
CAS_136434-34-9
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C18H19NOS
|
1
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| 1 |
IC50 = 15848.93 nM
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CP0424604
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,69,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N51O45S7
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2
|
| 1 |
IC50 = 15900 nM
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|
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| 2 |
IC50 > 5000 nM
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|
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CP0348250
|
US9012443, 261
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C19H13F3N4O3S2
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2
|
| 1 |
IC50 = 16000 nM
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|
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| 2 |
IC50 > 30000 nM
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CP0253250
|
5-Fluoro-3-(6-isobutoxypyridin-3-yl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C20H22FN3O4S
|
1
|
| 1 |
IC50 = 16000 nM
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|
|
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CP0423590
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1-Methyl-N-(methylsulfonyl)-3-(4-(trifluoromethoxy)phenyl)-1H-indole-6-carboxamide
Show/Hide
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C18H15F3N2O4S
|
1
|
| 1 |
IC50 = 16000 nM
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|
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CP0460600
|
4-(5-cyano-6-(3,5- dichlorophenoxy)-3-pyridinyl)- 3-methoxy-N- (methylsulfonyl)benzamide
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C21H15Cl2N3O5S
|
1
|
| 1 |
IC50 = 16100 nM
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|
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CP0490523
|
(3aS,6aS)-5-[1-(2-fluorophenyl)indazol-4-yl]-1-(3-hydroxy-3-methylbutanoyl)-3,3a,4,6a-tetrahydro-2H-pyrrolo[2,3-c]pyrrol-6-one
Show/Hide
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C24H25FN4O3
|
1
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| 1 |
IC50 = 16400 nM
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|
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CP0034615
|
(6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
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C20H24N2O2
|
1
|
| 1 |
IC50 = 16600 nM
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|
|
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CP0040250
|
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
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C21H25N3O2S
|
1
|
| 1 |
IC50 = 16900 nM
|
|
|
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CP0550182
|
US9546164, 135
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C25H28F4N2O5S
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0130944
|
4-[4-chloro-2-(1H-pyrazol-4-yl)phenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C18H11ClN6O3S2
|
1
|
| 1 |
IC50 = 17060 nM
|
|
|
|
CP0508107
|
5-chloro-N-(5-chloro-1,3-thiazol-2-yl)-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)benzenesulfonamide
Show/Hide
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C17H19Cl2FN4O2S2
|
1
|
| 1 |
IC50 = 17600 nM
|
|
|
|
CP0536473
|
4-(5-chloro-6-cyclobutyloxypyridin-3-yl)-3-methoxy-N-methylsulfonylbenzamide
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C18H19ClN2O5S
|
1
|
| 1 |
IC50 = 17800 nM
|
|
|
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CP0419575
|
(3,5-dimethylphenyl)-spiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-ylmethanone
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C24H25N3O
|
1
|
| 1 |
IC50 = 17810 nM
|
|
|
|
CP0389791
|
4-[[(1R,2R,3aS,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
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C22H31N3O
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0508343
|
3-(4-Isobutoxyphenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C21H24N2O4S
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
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CP0543825
|
N-((3,4-difluorophenyl)sulfonyl)-1-methyl-3-(4-(trifluoromethyl)phenyl)-1H-indole-6-carboxamide
Show/Hide
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C23H15F5N2O3S
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0530168
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-2-fluoro-N-methylsulfonylbenzamide
Show/Hide
|
C17H18ClFN2O4S
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0550631
|
4-(5-chloro-6-(cyclobutyloxy)-3-pyridinyl)-2-fluoro-5-
Show/Hide
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C18H18ClFN2O5S
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0270492
|
CHEMBL4104727
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|
C16H17ClFN3O4S2
|
1
|
| 1 |
IC50 = 18300 nM
|
|
|
|
CP0253363
|
3-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindole-6-carboxamide
Show/Hide
|
C20H22ClN3O4S
|
2
|
| 1 |
IC50 = 18347 nM
|
|
|
| 2 |
IC50 = 19000 nM
|
|
|
|
CP0851203
|
VERNAKALANT HYDROCHLORIDE
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|
C20H32ClNO4
|
1
|
| 1 |
IC50 = 18600 nM
|
|
|
|
CP0460599
|
4-(6-(3,5-dichlorophenoxy)-5- (difluoromethyl)-3-pyridinyl)- 3-methoxy-N- (methylsulfonyl)benzamide
Show/Hide
|
C21H16Cl2F2N2O5S
|
1
|
| 1 |
IC50 = 18800 nM
|
|
|
|
CP0409811
|
2-{3-[1-(2-fluorophenyl)-1H-indazol-4-yl]-2-oxoimidazolidin-1-yl}acetamide
Show/Hide
|
C18H16FN5O2
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0448656
|
5-chloro-2-fluoro-N-(6-fluoropyridin-2-yl)-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)benzenesulfonamide
Show/Hide
|
C19H21ClF2N4O2S
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0432061
|
3-(4-(Difluoromethyl)phenyl)-N?N,N-dimethylsulfamoyl)-1-methyl-1H-indole-6-carboxamide
Show/Hide
|
C19H18F3N3O3S
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0559763
|
US9012443, 495
Show/Hide
|
C27H21ClN4O3S
|
1
|
| 1 |
IC50 = 19100 nM
|
|
|
|
CP0478421
|
5-chloro-2-fluoro-4-[(4-hydroxy-1-adamantyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C20H23ClFN3O3S2
|
1
|
| 1 |
IC50 = 19400 nM
|
|
|
|
CP0573302
|
US9012443, 30
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C19H14ClN3O3S2
|
1
|
| 1 |
IC50 = 19900 nM
|
|
|
|
CP0382877
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57-methyl-80-(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C173H265N53O45S7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0399113
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-69-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C173H264N50O45S7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0509138
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,66S,69R,74R,77S,83S,86S,89S,92S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,92-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-83-benzyl-4-[(2S)-butan-2-yl]-45,66,89-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-63-methyl-57,77-bis(2-methylpropyl)-86-(2-methylsulfanylethyl)-a,2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,65,68,75,78,81,84,87,90,93-octacosaoxo-54-propan-2-yl-27,28,71,72,96,97-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,64,67,76,79,82,85,88,91,94,99-octacosazatetracyclo[49.43.4.225,69.06,10]hectan-74-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C174H269N53O45S7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0484820
|
1-Methyl-N-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-1H-indole-6-carboxamide
Show/Hide
|
C18H15F3N2O3S
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0567828
|
US9012443, 232
Show/Hide
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C20H14F3N3O4S2
|
1
|
| 1 |
IC50 = 20400 nM
|
|
|
|
CP0528913
|
US9012443, 332
Show/Hide
|
C24H16ClFN4O3S2
|
1
|
| 1 |
IC50 = 20700 nM
|
|
|
|
CP0385064
|
5-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-4-yl)naphthalene-2-sulfonamide
Show/Hide
|
C21H15F3N2O3S2
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0446143
|
5-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)naphthalene-2-sulfonamide
Show/Hide
|
C21H15F3N2O3S2
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0519553
|
US9012443, 23
Show/Hide
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C19H11BrF3N3O2S2
|
2
|
| 1 |
IC50 = 21000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0508344
|
3-[5-cyano-6-(2-methylpropoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindole-6-carboxamide
Show/Hide
|
C21H22N4O4S
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0460605
|
4-(5-Chloro-6-((4-Chlorobenzyl)Oxy)Pyridin-3-yl)-3-Methoxy-N-(Methylsulfonyl)Benzamide
Show/Hide
|
C21H18Cl2N2O5S
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0560749
|
US9012443, 8
Show/Hide
|
C18H12ClN3O2S2
|
1
|
| 1 |
IC50 = 21300 nM
|
|
|
|
CP0406958
|
US8952169, 283
Show/Hide
|
C23H28ClFN2O4S
|
1
|
| 1 |
IC50 = 21600 nM
|
|
|
|
CP0014894
|
3,5-diamino-6-(1-benzofuran-2-yl)-N-(diaminomethylidene)pyrazine-2-carboxamide
Show/Hide
|
C14H13N7O2
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0153084
|
4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C18H12ClF2N5O3S2
|
1
|
| 1 |
IC50 = 22210 nM
|
|
|
|
CP0569881
|
3,5-diethyl-4-[(N'-ethylcarbamimidoyl)carbamoylamino]-N-propan-2-ylbenzamide
Show/Hide
|
C18H29N5O2
|
1
|
| 1 |
IC50 = 22400 nM
|
|
|
|
CP0119708
|
5-chloro-2-fluoro-4-[2-pyridazin-4-yl-4-(trifluoromethyl)phenoxy]-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C20H11ClF4N4O3S2
|
1
|
| 1 |
IC50 = 22451 nM
|
|
|
|
CP0548771
|
5-chloro-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-(4-methyl-1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C18H22ClFN4O2S2
|
1
|
| 1 |
IC50 = 22500 nM
|
|
|
|
CP0399326
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-3-fluoropiperidin-1-yl]-2-oxoethyl}imidazolidin-2-one
Show/Hide
|
C23H23F2N5O2
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0575059
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-3-fluoro-N-methylsulfonylbenzamide
Show/Hide
|
C17H18ClFN2O4S
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0460603
|
4-(5-chloro-6-(2,5- difluorophenoxy)-3-pyridinyl)- 3-methoxy-N- (methylsulfonyl)benzamide
Show/Hide
|
C20H15ClF2N2O5S
|
1
|
| 1 |
IC50 = 23700 nM
|
|
|
|
CP0557023
|
US9012443, 9
Show/Hide
|
C18H13N3O2S2
|
1
|
| 1 |
IC50 = 23800 nM
|
|
|
|
CP0573301
|
US9012443, 5
Show/Hide
|
C18H11ClFN3O2S2
|
1
|
| 1 |
IC50 = 23800 nM
|
|
|
|
CP0552640
|
3-(5-Chloro-6-isobutoxypyridin-3-yl)-1-isobutyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
|
C23H28ClN3O4S
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0528187
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-3-cyano-N-methylsulfonylbenzamide
Show/Hide
|
C18H18ClN3O4S
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0542508
|
N-benzyl-3,5-diethyl-4-[(N'-ethylcarbamimidoyl)carbamoylamino]benzamide
Show/Hide
|
C22H29N5O2
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0560748
|
US9012443, 3
Show/Hide
|
C18H11BrFN3O2S2
|
1
|
| 1 |
IC50 = 24200 nM
|
|
|
|
CP0404562
|
5-chloro-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-(5-methyl-1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C18H22ClFN4O2S2
|
1
|
| 1 |
IC50 = 24200 nM
|
|
|
|
CP0556178
|
5-chloro-2-fluoro-4-[2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)ethylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C18H22ClFN4O2S2
|
1
|
| 1 |
IC50 = 24200 nM
|
|
|
|
CP0052826
|
4-[[(1R,2R)-2-(4-chlorophenyl)cyclohexyl]methoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H20ClF2N3O3S2
|
1
|
| 1 |
IC50 = 24700 nM
|
|
|
|
CP0235883
|
4-[4-chloro-2-(1H-pyrazol-5-yl)phenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C18H11ClN6O3S2
|
1
|
| 1 |
IC50 = 25231 nM
|
|
|
|
CP0895639
|
(1R,2R)-2-[(3S)-Hydroxypyrrolidinyl]-1-(3,4-dimethoxyphenethoxy)cyclohexane monohydrochloride
Show/Hide
|
C20H32ClNO4
|
1
|
| 1 |
IC50 = 25400 nM
|
|
|
|
CP0051985
|
4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-cyano-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Show/Hide
|
C19H13ClN6O3S2
|
1
|
| 1 |
IC50 = 25448 nM
|
|
|
|
CP0186940
|
3-cyano-4-[2-pyrimidin-4-yl-4-(trifluoromethyl)phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H11F3N6O3S2
|
1
|
| 1 |
IC50 = 25578 nM
|
|
|
|
CP0185901
|
5-chloro-4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
|
C19H13Cl2FN4O3S2
|
1
|
| 1 |
IC50 = 25786 nM
|
|
|
|
CP0518622
|
US9012443, 351
Show/Hide
|
C27H19F3N4O3S
|
1
|
| 1 |
IC50 = 26600 nM
|
|
|
|
CP0676320
|
(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-86-methyl-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
Show/Hide
|
C170H267N53O45S7
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0864600
|
2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Show/Hide
|
C13H14F3N3O
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0456376
|
4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5,5-difluoro-7a-methyl-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H29F2N3O
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0908543
|
(R)-2-(4-(2-Chloro-5-fluorobenzoyl)piperazin-1-yl)-2-(4-cyanophenyl)-N-(2-cyclopropyl2,2-difluoroethyl)acetamide
Show/Hide
|
C25H24ClF3N4O2
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0460608
|
US9012443, 57
Show/Hide
|
C18H10ClF3N4O2S2
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0559521
|
US9546164, 104
Show/Hide
|
C24H28ClFN2O4S
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0530956
|
3-chloro-5-[4-(5-cyclobutylsulfonyl-1H-1,2,4-triazol-3-yl)-2-fluorophenyl]-2-(2-methylpropoxy)pyridine
Show/Hide
|
C21H22ClFN4O3S
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0482700
|
4-[[(1R,2R,3aS,5S,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-(difluoromethyl)-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C23H31F2N3O
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0008828
|
4-[4-chloro-2-[2-(1-methylazetidin-3-yl)pyrazol-3-yl]phenoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C21H17ClF2N6O3S2
|
1
|
| 1 |
IC50 = 29291 nM
|
|
|
|
CP0357679
|
N-[2-[(3R)-3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]-5-(trifluoromethyl)pyridin-4-yl]-6-(1-methylpyrazol-4-yl)pyridine-2-carboxamide
Show/Hide
|
C23H25F3N6O2
|
1
|
| 1 |
IC50 = 29900 nM
|
|
|
|
CP0399552
|
(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,3'-azetidine]-1'-yl)-quinolin-6-ylmethanone
Show/Hide
|
C24H20N4O2
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0401671
|
3-(dimethylamino)-4-methoxy-N-(7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-cyclohexane]-1'-yl)benzamide
Show/Hide
|
C27H32N4O3
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0427954
|
N-(4-cyanophenyl)-7-methoxyspiro[5H-pyrrolo[1,2-a]quinoxaline-4,4'-piperidine]-1'-carboxamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412125
|
US9012443, 51
Show/Hide
|
C19H11ClF3N3O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412126
|
US9012443, 27
Show/Hide
|
C21H14ClN5O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412160
|
US9012443, 199
Show/Hide
|
C26H19FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412168
|
US9012443, 259
Show/Hide
|
C19H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0424099
|
US9012443, 445
Show/Hide
|
C26H18F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0424101
|
US9012443, 471
Show/Hide
|
C27H21FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0424455
|
US9012443, 293
Show/Hide
|
C19H13F3N4O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0426470
|
US9012443, 341
Show/Hide
|
C25H16FN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0429143
|
US9012443, 392
Show/Hide
|
C19H12F4N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0429144
|
US9012443, 394
Show/Hide
|
C18H12F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0429145
|
US9012443, 443
Show/Hide
|
C27H22N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0429147
|
US9012443, 498
Show/Hide
|
C23H15ClFN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0429148
|
US9012443, 515
Show/Hide
|
C20H16F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0463394
|
US9012443, 441
Show/Hide
|
C27H22N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0463395
|
US9012443, 468
Show/Hide
|
C27H22N4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0463401
|
US9012443, 338
Show/Hide
|
C25H15F2N5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0463402
|
US9012443, 360
Show/Hide
|
C25H26N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0470632
|
US9012443, 469
Show/Hide
|
C28H24N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0472817
|
US9012443, 271
Show/Hide
|
C18H13FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0472818
|
US9012443, 346
Show/Hide
|
C18H13ClN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0472820
|
US9012443, 459
Show/Hide
|
C24H20F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0476893
|
US9012443, 363
Show/Hide
|
C25H18FN5O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0478181
|
US9012443, 25
Show/Hide
|
C22H16ClN5O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0478187
|
US9012443, 460
Show/Hide
|
C27H21ClN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0478199
|
US9012443, 512
Show/Hide
|
C19H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0481753
|
US9012443, 442
Show/Hide
|
C27H22N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0481755
|
US9012443, 490
Show/Hide
|
C26H18ClFN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0481756
|
US9012443, 448
Show/Hide
|
C26H18F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0481757
|
US9012443, 467
Show/Hide
|
C27H22N4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0481758
|
US9012443, 492
Show/Hide
|
C26H18ClFN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0482707
|
US9012443, 530
Show/Hide
|
C23H15F2N5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483072
|
US9012443, 529
Show/Hide
|
C23H16FN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483074
|
US9012443, 350
Show/Hide
|
C26H19FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483075
|
US9012443, 406
Show/Hide
|
C19H15N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483076
|
US9012443, 419
Show/Hide
|
C20H13ClF3N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483077
|
US9012443, 449
Show/Hide
|
C26H18F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483845
|
US9012443, 375
Show/Hide
|
C22H13F3N4O5S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483847
|
US9012443, 522
Show/Hide
|
C23H15ClFN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483848
|
US9012443, 343
Show/Hide
|
C26H16F2N4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483849
|
US9012443, 349
Show/Hide
|
C27H19F3N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483851
|
US9012443, 355
Show/Hide
|
C24H16F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483852
|
US9012443, 361
Show/Hide
|
C24H24N4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483853
|
US9012443, 398
Show/Hide
|
C20H13FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0490187
|
US9012443, 491
Show/Hide
|
C26H18ClFN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0494126
|
US9012443, 29
Show/Hide
|
C19H11ClF3N3O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0495039
|
US9012443, 511
Show/Hide
|
C20H15F3N4O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0495052
|
US9012443, 509
Show/Hide
|
C25H18FN5O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0495556
|
US9012443, 493
Show/Hide
|
C27H21ClN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512089
|
US9012443, 369
Show/Hide
|
C24H17FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512095
|
US9012443, 464
Show/Hide
|
C26H19FN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512096
|
US9012443, 472
Show/Hide
|
C27H21FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512625
|
US9012443, 528
Show/Hide
|
C26H18F3N5O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512626
|
US9012443, 532
Show/Hide
|
C17H12ClN5O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512670
|
US9012443, 366
Show/Hide
|
C24H16F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0512675
|
US9012443, 272
Show/Hide
|
C18H14N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516812
|
US9012443, 337
Show/Hide
|
C19H12ClN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516814
|
US9012443, 348
Show/Hide
|
C26H19FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516815
|
US9012443, 358
Show/Hide
|
C26H19FN4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516817
|
US9012443, 373
Show/Hide
|
C22H12ClF3N4O5S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516818
|
US9012443, 393
Show/Hide
|
C18H13FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516819
|
US9012443, 452
Show/Hide
|
C21H17F2N3O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516820
|
US9012443, 494
Show/Hide
|
C27H21ClN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516823
|
US9012443, 510
Show/Hide
|
C20H15F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0516827
|
US9012443, 507
Show/Hide
|
C18H12ClFN4O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0518595
|
US9012443, 531
Show/Hide
|
C23H15F2N5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0518920
|
US9012443, 53
Show/Hide
|
C23H14F3N5O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0518930
|
US9012443, 370
Show/Hide
|
C27H20F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0519516
|
US9012443, 444
Show/Hide
|
C26H18F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0519522
|
US9012443, 486
Show/Hide
|
C27H18FN5O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0519554
|
US9012443, 50
Show/Hide
|
C18H10BrF3N4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0519555
|
US9012443, 32
Show/Hide
|
C20H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0521520
|
US9012443, 192
Show/Hide
|
C20H13FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0522196
|
US9012443, 322
Show/Hide
|
C18H13ClN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0522199
|
US9012443, 320
Show/Hide
|
C18H14N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0522200
|
US9012443, 339
Show/Hide
|
C26H16F3N5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0525117
|
US9012443, 374
Show/Hide
|
C21H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0531784
|
US9012443, 497
Show/Hide
|
C20H14F3N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0536210
|
US9012443, 347
Show/Hide
|
C24H17FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0536214
|
US9012443, 525
Show/Hide
|
C23H16FN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0536217
|
US9012443, 289
Show/Hide
|
C19H15N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0536218
|
US9012443, 344
Show/Hide
|
C25H17F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0536219
|
US9012443, 368
Show/Hide
|
C18H13ClN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0542038
|
US9012443, 345
Show/Hide
|
C24H17FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0542061
|
US9012443, 31
Show/Hide
|
C18H13ClN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0542072
|
US9012443, 364
Show/Hide
|
C24H15F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0545656
|
US9012443, 488
Show/Hide
|
C27H21FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0550477
|
US9012443, 365
Show/Hide
|
C24H15F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0550478
|
US9012443, 371
Show/Hide
|
C27H20F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0550479
|
US9012443, 421
Show/Hide
|
C21H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0550481
|
US9012443, 501
Show/Hide
|
C18H13ClN4O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0556262
|
US9012443, 40
Show/Hide
|
C18H11Cl2N3O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0557024
|
US9012443, 14 (isomer 1)
Show/Hide
|
C22H20N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0557038
|
US9012443, 195
Show/Hide
|
C19H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0557733
|
US9012443, 446
Show/Hide
|
C26H18F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0557736
|
US9012443, 447
Show/Hide
|
C26H18F2N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0559729
|
US9012443, 321
Show/Hide
|
C26H19FN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0559758
|
US9012443, 330
Show/Hide
|
C20H14N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0559759
|
US9012443, 336
Show/Hide
|
C19H12ClN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0559760
|
US9012443, 354
Show/Hide
|
C24H17FN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0559761
|
US9012443, 405
Show/Hide
|
C19H14FN3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0559762
|
US9012443, 484
Show/Hide
|
C27H21FN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560750
|
US9012443, 54
Show/Hide
|
C22H15F3N6O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560751
|
US9012443, 55
Show/Hide
|
C21H13F3N6O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560752
|
US9012443, 22
Show/Hide
|
C20H11F3N4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560947
|
US9012443, 340
Show/Hide
|
C25H16FN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560948
|
US9012443, 342
Show/Hide
|
C26H17FN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560951
|
US9012443, 470
Show/Hide
|
C28H24N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560955
|
US9012443, 177
Show/Hide
|
C19H13Cl2N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560956
|
US9012443, 513
Show/Hide
|
C19H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560957
|
US9012443, 524
Show/Hide
|
C17H12ClN5O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0561420
|
US9012443, 487
Show/Hide
|
C27H18FN5O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0561481
|
US9012443, 324
Show/Hide
|
C20H14N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0562167
|
US9012443, 466
Show/Hide
|
C27H22N4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0564957
|
US9012443, 26
Show/Hide
|
C23H19ClN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0564958
|
US9012443, 28
Show/Hide
|
C23H15ClN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0564964
|
US9012443, 505
Show/Hide
|
C17H12ClN5O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0566233
|
US9012443, 485
Show/Hide
|
C27H21FN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0568286
|
US9012443, 462
Show/Hide
|
C26H19FN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0568287
|
US9012443, 514
Show/Hide
|
C20H15F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0572384
|
US9012443, 2
Show/Hide
|
C24H15F3N4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0572399
|
US9012443, 175
Show/Hide
|
C20H17N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0040824
|
US9067922, 1
Show/Hide
|
C19H10ClFN4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0040825
|
US9067922, 247
Show/Hide
|
C19H13ClFN3O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0657167
|
2-(Trifluoromethyl)-N-(5-(trifluoromethyl)pyridin-3-yl)-benzenesulfonamide
Show/Hide
|
C13H8F6N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0345285
|
3-cyano-4-[2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C19H11F3N6O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0385060
|
US9012443, 291
Show/Hide
|
C19H13F3N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0385061
|
US9012443, 196
Show/Hide
|
C20H14F3N3O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0385062
|
US9012443, 42
Show/Hide
|
C22H16F3N3O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0432747
|
5-[2-(1,2,3,6-tetrahydropyridin-4-yl)-4-(trifluoromethyl)phenyl]-N-(1,2,4-thiadiazol-5-yl)naphthalene-2-sulfonamide
Show/Hide
|
C24H19F3N4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0445967
|
5-[2-methoxy-4-(trifluoromethyl)phenyl]-N-pyrimidin-2-ylnaphthalene-2-sulfonamide
Show/Hide
|
C22H16F3N3O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0133600
|
US9212182, 469
Show/Hide
|
C26H19ClFN3O5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412026
|
US9212182, 467
Show/Hide
|
C26H18ClFN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0426228
|
US9212182, 465
Show/Hide
|
C26H18ClFN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0413347
|
US9212182, 461
Show/Hide
|
C25H16Cl2FN3O5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0419362
|
US9212182, 533
Show/Hide
|
C26H17ClF3N3O5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0426479
|
US9212182, 477
Show/Hide
|
C25H16ClF2N3O5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0483989
|
US9212182, 353
Show/Hide
|
C24H16ClFN4O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0525225
|
US9212182, 423
Show/Hide
|
C26H19F2N3O5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0526415
|
US9212182, 475
Show/Hide
|
C25H17ClFN3O5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0069378
|
4-[2-(4-amino-1-phenylcyclohexyl)ethoxy]-5-chloro-2-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H24ClFN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0069379
|
4-[2-(4-amino-1-phenylcyclohexyl)ethylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C23H26ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0102361
|
4-[(1-acetylpiperidin-3-yl)methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H20ClFN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0102362
|
5-chloro-2-fluoro-4-[(1,2,2,6,6-pentamethylpiperidin-4-yl)amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C19H26ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0103654
|
4-[2-(4-amino-1-phenylcyclohexyl)ethoxy]-5-chloro-2-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H24ClFN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0162104
|
4-[2-[4-amino-1-(4-chlorophenyl)cyclohexyl]ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H23ClF2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0162105
|
4-[2-(4-amino-1-phenylcyclohexyl)ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H24F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0162106
|
2,5-difluoro-4-[2-[4-(methylamino)-1-phenylcyclohexyl]ethoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C23H26F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0162107
|
CHEMBL4097237
Show/Hide
|
C16H20ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0162108
|
5-chloro-2-fluoro-4-[[(3S)-piperidin-3-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C15H18ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0162110
|
4-(azetidin-3-ylmethylamino)-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C13H14ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0196967
|
4-[2-(4-amino-1-methylcyclohexyl)ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C17H22F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0214917
|
5-chloro-2-fluoro-4-(morpholin-2-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C14H16ClFN4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0240373
|
5-chloro-2-fluoro-4-(2-piperidin-4-ylethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H20ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0311329
|
4-[2-[4-amino-1-(4-chlorophenyl)cyclohexyl]ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H23ClF2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0311330
|
4-[2-(azetidin-3-yl)ethylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C14H16ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0370031
|
4-[2-(4-amino-1-phenylcyclohexyl)ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C22H24F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0370032
|
CHEMBL4072007
Show/Hide
|
C23H26F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0370033
|
4-[2-[4-(cyclopropylamino)-1-phenylcyclohexyl]ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C25H28F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0370034
|
5-chloro-2-fluoro-4-[(1-methylpiperidin-3-yl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C16H20ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0394474
|
CHEMBL4063378
Show/Hide
|
C25H28F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0405257
|
4-[2-(4-amino-1-methylcyclohexyl)ethoxy]-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C17H22F2N4O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0477679
|
5-chloro-2-fluoro-4-[2-(1-methylpiperidin-4-yl)ethylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H22ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0546717
|
5-chloro-2-fluoro-4-(2-pyrrolidin-3-ylethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C15H18ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0555578
|
4-[2-(4-amino-1-phenylcyclohexyl)ethylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C23H26ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0323809
|
US9012443, 67
Show/Hide
|
C21H15F3N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0387258
|
US9212182, 463
Show/Hide
|
C20H14F3N3O4S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0387294
|
US9212182, 672
Show/Hide
|
C27H19F3N4O4S
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
IC50 > 42500 nM
|
|
|
|
CP0072598
|
5-chloro-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H20ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0102247
|
5-chloro-4-[[(8R)-6,6-dimethyl-2,3,5,7-tetrahydro-1H-pyrrolizin-8-yl]methylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C19H24ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0389265
|
5-chloro-2-fluoro-4-(1,2,3,4,6,7,8,9-octahydroquinolizin-9a-ylmethylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C19H24ClFN4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0389266
|
5-chloro-2-fluoro-4-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H19ClF2N4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0423143
|
5-chloro-4-[(6,6-difluoro-2,3,5,7-tetrahydro-1H-pyrrolizin-8-yl)methylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
|
C17H18ClF3N4O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0423144
|
5-chloro-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-pyrimidin-4-ylbenzenesulfonamide
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C18H21ClFN5O2S
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1
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| 1 |
IC50 > 30000 nM
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CP0423147
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2,5-difluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C16H19F2N5O2S2
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1
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| 1 |
IC50 > 30000 nM
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CP0448647
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5-chloro-2-fluoro-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
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C17H20ClFN4O2S2
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1
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| 1 |
IC50 > 30000 nM
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CP0519944
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5-chloro-4-[[(8S)-6,6-dimethyl-2,3,5,7-tetrahydro-1H-pyrrolizin-8-yl]methylamino]-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C19H24ClFN4O2S2
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1
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| 1 |
IC50 > 30000 nM
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CP0534239
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5-chloro-2-fluoro-N-(5-fluoro-4-methyl-1,3-thiazol-2-yl)-4-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethylamino)benzenesulfonamide
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C18H21ClF2N4O2S2
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1
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| 1 |
IC50 > 30000 nM
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CP0457129
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3-benzyl-2-oxo-N-(1,2,4-thiadiazol-5-yl)-1,3-benzothiazole-6-sulfonamide
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C16H12N4O3S3
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1
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| 1 |
IC50 > 30000 nM
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CP0507020
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3-benzyl-2-oxo-N-(1,2,4-thiadiazol-5-yl)-1,3-benzoxazole-6-sulfonamide
Show/Hide
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C16H12N4O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0535860
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4-benzyl-3-oxo-N-(1,2,4-thiadiazol-5-yl)-1,4-benzoxazine-7-sulfonamide
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C17H14N4O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0119705
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5-chloro-4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-2-fluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Show/Hide
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C18H12Cl2FN5O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0130941
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4-[4-chloro-2-[2-(1-methylazetidin-3-yl)pyrazol-3-yl]phenoxy]-2,5-difluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
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C22H18ClF2N5O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0168191
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4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C19H13ClN6O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0247315
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4-[4-chloro-2-[2-(1-ethylazetidin-3-yl)pyrazol-3-yl]phenoxy]-3-cyano-N-(1,3-thiazol-4-yl)benzenesulfonamide
Show/Hide
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C24H21ClN6O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0254953
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5-chloro-2-fluoro-4-[2-pyridazin-4-yl-4-(trifluoromethyl)phenoxy]-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
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C19H10ClF4N5O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0161800
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5-chloro-2-fluoro-4-[(3-hydroxy-1-adamantyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C20H23ClFN3O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0315132
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5-chloro-2-fluoro-4-(7-oxabicyclo[2.2.1]heptan-2-ylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C15H15ClFN3O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0315133
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4-[[(2R,3R)-2-tert-butyloxan-3-yl]methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C19H25ClFN3O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0315134
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5-chloro-2-fluoro-4-(2-oxaspiro[3.3]heptan-6-ylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
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C15H15ClFN3O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0326740
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4-[[(2S,3R)-2-tert-butyloxan-3-yl]methylamino]-5-chloro-2-fluoro-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C19H25ClFN3O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0334668
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5-chloro-2-fluoro-4-(oxan-4-ylamino)-N-(1,3-thiazol-2-yl)benzenesulfonamide
Show/Hide
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C14H15ClFN3O3S2
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1
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| 1 |
IC50 > 30000 nM
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CP0319375
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US9012443, 48
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C26H21F3N4O2S
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1
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| 1 |
IC50 > 30000 nM
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CP0478052
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4-[[(1R,2R,3aR,5E,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-methoxyimino-7a-methyl-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
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C23H32N4O2
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1
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| 1 |
IC50 > 30000 nM
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CP0480989
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4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-7a-methyl-1,2,3,3a,6,7-hexahydroinden-1-yl]oxy]benzonitrile
Show/Hide
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C22H28FN3O
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1
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| 1 |
IC50 > 30000 nM
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CP0482699
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4-[[(1R,2R,3aR,5R,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-methoxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
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C23H33N3O2
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1
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| 1 |
IC50 > 30000 nM
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CP0519974
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4-[[(1R,2R,3aR,5S,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-methoxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
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C23H33N3O2
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1
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| 1 |
IC50 > 30000 nM
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CP0390902
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2,5-difluoro-4-[3-(3-methoxyphenyl)morpholin-2-yl]oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C19H18F2N4O5S2
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1
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| 1 |
IC50 > 30000 nM
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CP0390903
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4-[3-(4-cyanophenyl)morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C19H15F2N5O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0390904
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4-[3-(6-chloropyridin-3-yl)morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C17H14ClF2N5O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0414931
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2,5-difluoro-4-(3-isoquinolin-6-ylmorpholin-2-yl)oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C21H17F2N5O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0414932
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2,5-difluoro-4-(3-quinolin-6-ylmorpholin-2-yl)oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C21H17F2N5O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0415574
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2,5-difluoro-4-(3-quinoxalin-5-ylmorpholin-2-yl)oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C20H16F2N6O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0427626
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4-[3-(3-cyanophenyl)morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C19H15F2N5O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0427627
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2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)-4-[3-[4-(trifluoromethyl)phenyl]morpholin-2-yl]oxybenzenesulfonamide
Show/Hide
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C19H15F5N4O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0427629
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2,5-difluoro-4-[3-(2-methoxyphenyl)morpholin-2-yl]oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C19H18F2N4O5S2
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1
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| 1 |
IC50 > 30000 nM
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CP0467754
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2,5-difluoro-4-[3-(4-methoxyphenyl)morpholin-2-yl]oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C19H18F2N4O5S2
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1
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| 1 |
IC50 > 30000 nM
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CP0467755
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2,5-difluoro-4-[3-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]morpholin-2-yl]oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C17H15F5N6O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0473789
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4-[3-(1,3-benzodioxol-5-yl)morpholin-2-yl]oxy-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C19H16F2N4O6S2
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1
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| 1 |
IC50 > 30000 nM
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CP0545889
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2,5-difluoro-4-[3-(2-methylpyrazol-3-yl)morpholin-2-yl]oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C16H16F2N6O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0549507
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2,5-difluoro-4-[3-(4-fluorophenyl)morpholin-2-yl]oxy-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
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C18H15F3N4O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0387389
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5-fluoro-1-methyl-N-methylsulfonyl-3-[4-(trifluoromethyl)phenyl]indole-6-carboxamide
Show/Hide
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C18H14F4N2O3S
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1
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| 1 |
IC50 = 30000 nM
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CP0423579
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3-[5-chloro-6-(2,2-difluoroethoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindole-6-carboxamide
Show/Hide
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C18H16ClF2N3O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0423584
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5-fluoro-1-methyl-3-[6-(2-methylpropoxy)pyridin-3-yl]-N-methylsulfonylindazole-6-carboxamide
Show/Hide
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C19H21FN4O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0431905
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1-methyl-3-[6-(2-methylpropoxy)pyridin-3-yl]-N-methylsulfonylindazole-6-carboxamide
Show/Hide
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C19H22N4O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0438674
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1-Methyl-N-(methylsulfonyl)-3-(p-tolyl)-1H-indole-6-carboxamide
Show/Hide
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C18H18N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0446677
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3-(3-Ethylphenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C19H20N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0451291
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N-cyclopropylsulfonyl-3-[5-methoxy-6-(2-methylpropoxy)pyridin-3-yl]-1-methylindole-6-carboxamide
Show/Hide
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C23H27N3O5S
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1
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| 1 |
IC50 > 30000 nM
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CP0482265
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1-Methyl-N-(methylsulfonyl)-3-(m-tolyl)-1H-indole-6-carboxamide
Show/Hide
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C18H18N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0482267
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1-methyl-N-methylsulfonyl-3-[4-(trifluoromethyl)phenyl]indazole-6-carboxamide
Show/Hide
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C17H14F3N3O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0482821
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N-(cyclopropylsulfonyl)-3-(4-(difluoromethyl)phenyl)-1-methyl-1H-indole-6-carboxamide
Show/Hide
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C20H18F2N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0484821
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3-[5-chloro-6-(2-hydroxy-2-methylpropoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindole-6-carboxamide
Show/Hide
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C20H22ClN3O5S
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1
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| 1 |
IC50 > 30000 nM
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CP0508342
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3-(4-Isobutylphenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C21H24N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0533510
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1-Methyl-N-(methylsulfonyl)-3-phenyl-1H-indole-6-carboxamide
Show/Hide
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C17H16N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0537941
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3-(2,3-Difluorophenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C17H14F2N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0537942
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3-[5-methoxy-6-(2-methylpropoxy)pyridin-3-yl]-1-methyl-N-methylsulfonylindole-6-carboxamide
Show/Hide
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C21H25N3O5S
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1
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| 1 |
IC50 > 30000 nM
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CP0538308
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5-fluoro-1-methyl-N-methylsulfonyl-3-[4-(trifluoromethyl)phenyl]indazole-6-carboxamide
Show/Hide
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C17H13F4N3O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0552687
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3-(4-Ethylphenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C19H20N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0561758
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3-(4-(Difluoromethyl)phenyl)-5-fluoro-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C18H15F3N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0569939
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3-(4-(Difluoromethyl)phenyl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C18H16F2N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0572702
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3-(6-Isobutoxypyridin-3-yl)-1-methyl-N-(methylsulfonyl)-1H-indole-6-carboxamide
Show/Hide
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C20H23N3O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0430201
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4-(3,4-dichlorophenoxy)-2,5-difluoro-N-methylsulfonylbenzamide
Show/Hide
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C14H9Cl2F2NO4S
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1
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| 1 |
IC50 > 30000 nM
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CP0460601
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1-[3-chloro-4-(trifluoromethyl)phenyl]-N-methylsulfonylisoquinoline-6-carboxamide
Show/Hide
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C18H12ClF3N2O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0483089
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4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-2,5-difluoro-N-methylsulfonylbenzamide
Show/Hide
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C17H17ClF2N2O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0555112
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4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-3-methoxy-N-methylsulfonylbenzamide
Show/Hide
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C18H21ClN2O5S
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1
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| 1 |
IC50 > 30000 nM
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CP0004656
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3,5-diamino-N-(diaminomethylidene)-6-(2-methoxypyrimidin-5-yl)pyrazine-2-carboxamide
Show/Hide
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C11H13N9O2
|
1
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| 1 |
IC50 > 30000 nM
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CP0083553
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3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride
Show/Hide
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C6H8ClN7O
|
1
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| 1 |
IC50 > 30000 nM
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CP0110087
|
CAS_1794
Show/Hide
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C12H18ClN7O
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1
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| 1 |
IC50 = 30000 nM
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CP0189395
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3-amino-5-(azepan-1-yl)-N-(diaminomethylidene)-6-(2-methoxypyrimidin-5-yl)pyrazine-2-carboxamide
Show/Hide
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C17H23N9O2
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1
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| 1 |
IC50 > 30000 nM
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CP0569879
|
Lidamidine
Show/Hide
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C11H16N4O
|
1
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| 1 |
IC50 > 30000 nM
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CP0569882
|
1-[2,6-diethyl-4-(ethylsulfamoyl)phenyl]-3-(N'-ethylcarbamimidoyl)urea
Show/Hide
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C16H27N5O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0574560
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1-[4-(benzenesulfonamido)-2,6-diethylphenyl]-3-(N'-ethylcarbamimidoyl)urea
Show/Hide
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C20H27N5O3S
|
1
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| 1 |
IC50 > 30000 nM
|
|
|
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CP0532839
|
BDBM70996
Show/Hide
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C24H29FN2O4S
|
1
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| 1 |
IC50 > 30000 nM
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|
|
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CP0543447
|
US9546164, 74
Show/Hide
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C22H25FN2O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0571036
|
N-[5-[(3R)-3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]-2-(trifluoromethyl)pyridin-3-yl]-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyridine-2-carboxamide
Show/Hide
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C24H24F6N6O2
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1
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| 1 |
IC50 = 30000 nM
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CP0875566
|
(1R,2R)/(1S,2S)-2-(3R)/(3S)-Hydroxypyrrolidinyl]-1-(3,4-dimethoxyphenethoxy)cyclohexane monohydrochloride
Show/Hide
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C20H32ClNO4
|
1
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| 1 |
IC50 = 30300 nM
|
|
|
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CP0456538
|
US9452986, 596
Show/Hide
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C20H16F3N3O2
|
1
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| 1 |
IC50 = 31300 nM
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|
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CP0007317
|
(+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol
Show/Hide
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C22H31NO
|
1
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| 1 |
IC50 = 31622.78 nM
|
|
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CP0528186
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-methylsulfonylbenzamide
Show/Hide
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C17H19ClN2O4S
|
1
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| 1 |
IC50 = 32000 nM
|
|
|
|
CP0380326
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C22H22FN5O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0399321
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethyl}imidazolidin-2-one
Show/Hide
|
C22H21F2N5O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0409746
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(6-methylpyrazin-2-yl)methyl]imidazolidin-2-one
Show/Hide
|
C22H19FN6O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0409748
|
(3aR,6aS)-5-[1-(2-fluorophenyl)indazol-4-yl]-2-(3-hydroxy-3-methylbutanoyl)-3,3a,6,6a-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-4-one
Show/Hide
|
C24H25FN4O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0409812
|
N-cyclopropyl-2-{3-[1-(2-fluorophenyl)-1H-indazol-4-yl]-2-oxoimidazolidin-1-yl}acetamide
Show/Hide
|
C21H20FN5O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0423888
|
US9452986, 597
Show/Hide
|
C19H14F3N3O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0423913
|
US9452986, 1
Show/Hide
|
C20H17F3N4O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0456547
|
US9452986, 52
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0478093
|
US9452986, 14
Show/Hide
|
C20H18F2N4O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0486238
|
US9452986, 59
Show/Hide
|
C20H14F5N3O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0488605
|
US9452986, 20
Show/Hide
|
C21H16F6N4O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0517253
|
US9452986, 149
Show/Hide
|
C20H16F3N3O3
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0519175
|
US9452986, 10
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0519487
|
US9452986, 604
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0531518
|
US9452986, 34
Show/Hide
|
C20H16F3N3O3
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0544395
|
US9452986, 181
Show/Hide
|
C22H18F6N4O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0545413
|
1-(4-methylpiperazin-1-yl)-2-(6-pyridin-2-yloxyquinolin-2-yl)oxyethanone
Show/Hide
|
C21H22N4O3
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0547422
|
US9452986, 251
Show/Hide
|
C19H16F3N3O4S
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0563172
|
US9452986, 51
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0563446
|
US9452986, 530
Show/Hide
|
C20H14F3N3O4
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0323607
|
3-cyano-4-[2-pyridazin-4-yl-4-(trifluoromethyl)phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H11F3N6O3S2
|
1
|
| 1 |
IC50 = 35118 nM
|
|
|
|
CP0658605
|
3-((5-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)methyl)oxetan-3-amine
Show/Hide
|
C14H14F3N3O2
|
1
|
| 1 |
IC50 = 36000 nM
|
|
|
|
CP0901759
|
(1S,2S)-2-[(3R)-Hydroxypyrrolidinyl]-1-(3,4-dimethoxyphenethoxy)-cyclohexane monohydrochloride
Show/Hide
|
C20H32ClNO4
|
1
|
| 1 |
IC50 = 36400 nM
|
|
|
|
CP0348995
|
N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C17H16ClN5O2
|
1
|
| 1 |
IC50 = 37000 nM
|
|
|
|
CP0872999
|
(1S,2S)-2-[(3S)-hydroxypyrrolidinyl]-l-(3,4-dimethoxyphenethoxy)cyclohexane monohydrochloride
Show/Hide
|
C20H32ClNO4
|
1
|
| 1 |
IC50 = 37200 nM
|
|
|
|
CP0048263
|
(1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime
Show/Hide
|
C15H21F3N2O2
|
1
|
| 1 |
IC50 = 39400 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C22H27FN4O2
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0002226
|
6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine
Show/Hide
|
C9H7Cl2N5
|
2
|
| 1 |
IC50 = 39810.72 nM
|
|
|
| 2 |
IC50 = 62000 nM
|
|
|
|
CP0056899
|
(2-Benzhydryloxy-ethyl)-dimethyl-amine
Show/Hide
|
C17H21NO
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
|
CP0036382
|
CAS_52-53-9
Show/Hide
|
C27H38N2O4
|
1
|
| 1 |
IC50 = 41500 nM
|
|
|
|
CP0958959
|
(R)-2-(4-Cyanophenyl)-N-(cyclopropylmethyl)-2-(8-(2,5-difluorobenzoyl)-3,8-diazabicyclo[3.2.1]octan-3-yl)acetamide
Show/Hide
|
C26H26F2N4O2
|
1
|
| 1 |
IC50 = 42000 nM
|
|
|
|
CP0966208
|
(R)-2-(4-Cyanophenyl)-N-(cyclopropylmethyl)-2-(8-(3,5-difluorobenzoyl)-3,8-diazabicyclo[3.2.1]octan-3-yl)acetamide
Show/Hide
|
C26H26F2N4O2
|
1
|
| 1 |
IC50 > 42000 nM
|
|
|
|
CP0430199
|
4-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-3-(2,5-dihydrofuran-3-yl)-N-methylsulfonylbenzamide
Show/Hide
|
C21H23ClN2O5S
|
1
|
| 1 |
IC50 > 42000 nM
|
|
|
|
CP0430202
|
4-(3,4-dichlorophenyl)-2,5-difluoro-N-methylsulfonylbenzamide
Show/Hide
|
C14H9Cl2F2NO3S
|
1
|
| 1 |
IC50 > 42000 nM
|
|
|
|
CP0483088
|
4-(3,4-dichlorophenyl)-N-methylsulfonylbenzamide
Show/Hide
|
C14H11Cl2NO3S
|
1
|
| 1 |
IC50 > 42000 nM
|
|
|
|
CP0193560
|
3-cyano-4-[2-pyridazin-3-yl-4-(trifluoromethyl)phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C20H11F3N6O3S2
|
1
|
| 1 |
IC50 = 43699 nM
|
|
|
|
CP0567642
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-2,5-bis(trifluoromethyl)benzamide
Show/Hide
|
C22H22F6N8O5
|
1
|
| 1 |
IC50 = 46000 nM
|
|
|
|
CP0036699
|
Phenytoin
Show/Hide
|
C15H12N2O2
|
1
|
| 1 |
IC50 = 49000 nM
|
|
|
|
CP0032416
|
7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methyl-2-oxoquinoline-3-carboxylic acid
Show/Hide
|
C20H24FN3O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0034173
|
7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methylquinolin-2-one
Show/Hide
|
C19H24FN3O
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0544060
|
(3aS,4R,9S,10aS)-2,6-diamino-9-benzoyloxy-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purine-4-carboxylic acid
Show/Hide
|
C16H18N6O6
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0571659
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxoimidazolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-4,4-dimethyl-2,3-dihydrochromene-8-carboxamide
Show/Hide
|
C24H31N9O6
|
1
|
| 1 |
IC50 = 77000 nM
|
|
|
|
CP0547806
|
7-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methyl-2-oxoquinoline-3-carboxylic acid
Show/Hide
|
C21H24FN3O3
|
1
|
| 1 |
IC50 = 92000 nM
|
|
|
|
CP0411708
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H23F3N8O5
|
1
|
| 1 |
IC50 = 95000 nM
|
|
|
|
CP0006743
|
4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
Show/Hide
|
C16H19NO3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0013112
|
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Show/Hide
|
C27H37N3O7S
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0648689
|
2-(Trifluoromethyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-benzenesulfonamide
Show/Hide
|
C13H8F6N2O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0390399
|
4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-hydroxy-5,7a-dimethyl-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
|
C23H33N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0390400
|
4-[[(1R,2R,3R,5R)-3-[(3R)-3-aminopiperidin-1-yl]-6-oxo-2-bicyclo[3.2.0]heptanyl]oxy]benzonitrile
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0390426
|
4-[[(1R,2R,3aS,7aR)-2-[(3R)-3-aminopiperidin-1-yl]-7a-methyl-5-oxo-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0475136
|
4-[[(1R,2R,3aR,6aR)-2-[(3R)-3-aminopiperidin-1-yl]-4-oxo-2,3,3a,5,6,6a-hexahydro-1H-pentalen-1-yl]oxy]benzonitrile
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0475137
|
4-[[(1R,2R,3aR,5R,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-hydroxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0475138
|
4-[[(1R,2R,3aR,5S,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-hydroxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0480990
|
(2E)-2-[(1R,2R,3aS,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-1-(4-cyanophenoxy)-7a-methyl-2,3,3a,4,6,7-hexahydro-1H-inden-5-ylidene]-N,N-dimethylacetamide
Show/Hide
|
C26H36N4O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0485521
|
4-[[(1S,2R,3R,4R,6R,7S)-4-[(3R)-3-aminopiperidin-1-yl]-9-oxo-3-tricyclo[5.2.1.02,6]decanyl]oxy]benzonitrile
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0567644
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Show/Hide
|
C24H30N8O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0569071
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-4,4-dimethyl-2,3-dihydrochromene-8-carboxamide
Show/Hide
|
C25H32N8O6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0569884
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-2,3-dihydro-1H-indene-4-carboxamide
Show/Hide
|
C23H28N8O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0579068
|
[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl] 2,5-bis(trifluoromethyl)benzoate
Show/Hide
|
C22H21F6N7O6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0572847
|
N-[(3aS,4S,9S,10aS)-2,6-diamino-10,10-dihydroxy-4-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-4,4-dimethyl-2,3-dihydrochromene-8-carboxamide
Show/Hide
|
C25H33N9O6
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0273514
|
2-N-[4-[4-(trifluoromethyl)phenoxy]phenyl]pyrimidine-2,4-diamine
Show/Hide
|
C17H13F3N4O
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0491026
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-4,48-bis(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C173H265N53O46S7
|
1
|
| 1 |
IC50 > 2700 nM
|
|
|
|
CP0474699
|
3-cyano-4-[2-[2-[[2-[1-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoyl]piperidin-4-yl]ethylamino]methyl]pyridin-4-yl]-4-[3-(trifluoromethyl)phenyl]phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
Show/Hide
|
C61H82F3N7O16S2
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0123962
|
3-amino-5-(azepan-1-yl)-6-(1-benzofuran-2-yl)-N-(diaminomethylidene)pyrazine-2-carboxamide
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 < 3000 nM
|
|
|
|
CP0447930
|
(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,83S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-83-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C187H279N53O45S7
|
1
|
| 1 |
IC50 > 4000 nM
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CP0377129
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-48-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N53O44S7
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1
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| 1 |
IC50 > 4700 nM
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CP0400883
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-13,22,36,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H278N54O43S7
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1
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| 1 |
IC50 > 4700 nM
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CP0408392
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-13,45,69,92-tetrakis(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H278N56O43S7
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1
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| 1 |
IC50 > 4800 nM
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|
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CP0545525
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4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-4-yl]methyl]benzoic acid
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C180H269N53O47S7
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1
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| 1 |
IC50 > 4800 nM
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|
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CP0382878
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,80,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57-(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H272N56O45S7
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1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0385025
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(3S)-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid
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C182H283N55O46S7
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1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0385026
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,54,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H274N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0385027
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-4-(1H-indol-2-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C181H270N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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|
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CP0385031
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2-[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-naphthalen-1-ylpropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-13-yl]acetic acid
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C185H277N53O43S7
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1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0385033
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-86-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C180H273N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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|
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CP0385034
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-80-(2-methylpropyl)-89-(2-methylsulfanylethyl)-57-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C183H271N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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|
|
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CP0386154
|
(3S)-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-3-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-4-oxobutanoic acid
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C182H283N57O46S7
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1
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| 1 |
IC50 > 5000 nM
|
|
|
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CP0399091
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,45,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-69,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N51O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0399103
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H272N54O44S7
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1
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IC50 > 5000 nM
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CP0399108
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-4,57,80-tris(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0399110
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C167H262N52O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0399111
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(3S)-3-amino-4-[[(1R,4S,7S,10S,13S,19S,22R,27R,30S,36S,39S,42S,45S,48R,51S,54S,57S,60S,63S,66S,69R,74R,77S,80S,83S,86S,89S,92S)-74-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-45,66,80-tris(4-aminobutyl)-10,60-bis(2-amino-2-oxoethyl)-36-benzyl-51-[(2S)-butan-2-yl]-19,42,89-tris(3-carbamimidamidopropyl)-57,63-bis(carboxymethyl)-86-[(1R)-1-hydroxyethyl]-92-(hydroxymethyl)-83-(1H-imidazol-5-ylmethyl)-77-(1H-indol-3-ylmethyl)-54-methyl-7,30-bis(2-methylpropyl)-39-(2-methylsulfanylethyl)-3,6,9,12,18,21,28,31,34,37,40,43,46,49,52,55,58,61,64,67,76,79,82,85,88,91,94,99-octacosaoxo-4-propan-2-yl-24,25,71,72,96,97-hexathia-a,2,5,8,11,17,20,29,32,35,38,41,44,47,50,53,56,59,62,65,68,75,78,81,84,87,90,93-octacosazatetracyclo[46.46.4.222,69.013,17]hectan-27-yl]amino]-4-oxobutanoic acid
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C174H269N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0399115
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(3S)-3-amino-4-[[(1S,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51S,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-33-(1H-indol-3-ylmethyl)-39-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H269N51O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0399116
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-95-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H266N52O47S7
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1
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IC50 > 5000 nM
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CP0399117
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-4-[(2S)-butan-2-yl]-45,69,86,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H274N56O45S7
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1
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IC50 > 5000 nM
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CP0399118
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-36,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-22,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N55O45S7
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1
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IC50 > 5000 nM
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CP0399119
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33,60-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C183H275N53O44S7
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1
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IC50 > 5000 nM
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CP0399120
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-36,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-22-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H264N52O45S7
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1
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IC50 > 5000 nM
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CP0399121
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(4S)-5-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-6-amino-2-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectane-30-carbonyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoic acid
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C176H269N53O47S7
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1
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IC50 > 5000 nM
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CP0400885
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H272N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0401789
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H273N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0401843
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-60-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-16,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H277N55O44S7
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1
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IC50 > 5000 nM
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CP0401844
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,60,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H277N55O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0401846
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(3S)-3-amino-4-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-30-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
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C176H271N55O45S7
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1
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IC50 > 5000 nM
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CP0401847
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H274N56O45S7
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1
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IC50 > 5000 nM
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CP0401848
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,42,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H276N54O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0402932
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(3S)-3-amino-4-[[(1R,4S,7S,10S,13S,19S,22R,27R,30S,36S,39S,42S,45S,48R,51S,54S,57S,60S,63S,66S,69R,74R,77S,80S,83S,86S,89S,92S)-74-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-45,66,80-tris(4-aminobutyl)-10,60-bis(2-amino-2-oxoethyl)-36-benzyl-51-[(2S)-butan-2-yl]-19,42,89-tris(3-carbamimidamidopropyl)-57,63-bis(carboxymethyl)-86-[(1R)-1-hydroxyethyl]-92-(hydroxymethyl)-83-(1H-imidazol-5-ylmethyl)-54,77-bis(1H-indol-3-ylmethyl)-7,30-bis(2-methylpropyl)-39-(2-methylsulfanylethyl)-3,6,9,12,18,21,28,31,34,37,40,43,46,49,52,55,58,61,64,67,76,79,82,85,88,91,94,99-octacosaoxo-4-propan-2-yl-24,25,71,72,96,97-hexathia-a,2,5,8,11,17,20,29,32,35,38,41,44,47,50,53,56,59,62,65,68,75,78,81,84,87,90,93-octacosazatetracyclo[46.46.4.222,69.013,17]hectan-27-yl]amino]-4-oxobutanoic acid
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C182H274N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0407477
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,83S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33,83-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C185H278N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0407478
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-13-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C185H277N53O43S7
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1
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| 1 |
IC50 > 5000 nM
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CP0407480
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-4,42-bis[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C174H267N53O46S7
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1
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| 1 |
IC50 > 5000 nM
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CP0407551
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-4,86-dibenzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C179H269N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0408752
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-16,22,36,95-tetrakis(4-aminobutyl)-60-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H277N53O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0414591
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H274N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0414593
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-60-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-16,33-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C183H275N53O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0414639
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C184H273N53O45S7
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1
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IC50 > 5000 nM
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CP0414647
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2-[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-13-yl]acetic acid
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C178H278N56O43S7
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1
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| 1 |
IC50 > 5000 nM
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CP0420070
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H274N56O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0420145
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-60-(naphthalen-1-ylmethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C185H276N52O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0420285
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,66S,69R,74R,77S,83S,86S,89S,92S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,92-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-83-benzyl-4-[(2S)-butan-2-yl]-45,63,66,89-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,77-bis(2-methylpropyl)-86-(2-methylsulfanylethyl)-a,2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,65,68,75,78,81,84,87,90,93-octacosaoxo-54-propan-2-yl-27,28,71,72,96,97-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,64,67,76,79,82,85,88,91,94,99-octacosazatetracyclo[49.43.4.225,69.06,10]hectan-74-yl]amino]-4-oxobutanoic acid
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C177H276N56O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0420633
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(3S)-3-amino-4-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
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C182H283N55O46S7
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1
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IC50 > 5000 nM
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CP0420674
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-42-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H269N53O44S7
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1
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IC50 > 5000 nM
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CP0424602
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-36,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-22-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H266N52O47S7
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1
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IC50 > 5000 nM
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CP0424603
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(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectane-30-carbonyl]amino]pentanoic acid
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C175H266N52O47S7
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1
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IC50 > 5000 nM
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CP0428556
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-69,92-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-45-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H264N50O45S7
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1
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IC50 > 5000 nM
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CP0428558
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-33-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C170H268N52O47S7
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1
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IC50 > 5000 nM
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CP0428559
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92,95-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N55O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0434632
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(3S)-3-amino-4-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
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C173H274N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0434633
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(3S)-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-3-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-4-oxobutanoic acid
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C187H281N55O46S7
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1
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| 1 |
IC50 > 5000 nM
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CP0434634
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33,86-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H272N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0434635
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-4,54-di(propan-2-yl)-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H269N53O45S7
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1
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IC50 > 5000 nM
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CP0434637
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(3S)-3-amino-4-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-30-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
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C153H244N50O41S7
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1
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IC50 > 5000 nM
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CP0434638
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-60-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-16-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H270N52O44S7
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1
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IC50 > 5000 nM
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CP0434639
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(4S)-4-amino-5-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-5-oxopentanoic acid
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C177H273N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0434640
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-89-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H269N53O47S6
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1
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| 1 |
IC50 > 5000 nM
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CP0434641
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-69,92-bis(3-carbamimidamidopropyl)-45-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H266N50O47S7
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1
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| 1 |
IC50 > 5000 nM
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CP0434642
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(4R)-5-amino-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectane-30-carbonyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoic acid
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C181H278N54O48S7
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1
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IC50 > 5000 nM
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CP0434643
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,54,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H274N56O45S7
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1
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IC50 > 5000 nM
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CP0434657
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,60,95-tetrakis(4-aminobutyl)-16-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H277N53O44S7
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1
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IC50 > 5000 nM
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CP0443463
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-86-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C172H269N53O47S7
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1
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| 1 |
IC50 > 5000 nM
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CP0443465
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-13-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H271N53O43S7
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1
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| 1 |
IC50 > 5000 nM
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CP0447927
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2-[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-13-yl]acetic acid
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C183H276N54O43S7
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1
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IC50 > 5000 nM
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CP0447935
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C162H253N51O43S7
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1
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IC50 > 5000 nM
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CP0448025
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-39-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H271N51O47S7
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1
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IC50 > 5000 nM
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CP0452636
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(4S)-4-amino-5-[[(2S)-1-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
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C181H278N54O48S7
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1
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IC50 > 5000 nM
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CP0452637
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-42-(2-carboxyethyl)-13,19-bis(carboxymethyl)-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H271N53O46S7
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1
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IC50 > 5000 nM
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CP0459525
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-33,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C171H273N55O45S7
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1
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IC50 > 5000 nM
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CP0459578
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,33,36,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C171H273N53O45S7
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1
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IC50 > 5000 nM
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CP0464416
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(4S)-5-amino-4-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectane-30-carbonyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoic acid
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C172H269N53O47S7
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1
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IC50 > 5000 nM
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CP0464419
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H274N54O44S7
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1
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IC50 > 5000 nM
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CP0467969
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25S,30R,33S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-36-[3-[(N,N'-dimethylcarbamimidoyl)amino]propyl]-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H275N55O45S7
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1
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IC50 > 5000 nM
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CP0469684
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-60-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H272N52O46S7
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1
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IC50 > 5000 nM
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CP0469685
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,80,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57-(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H272N54O45S7
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1
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IC50 > 5000 nM
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CP0473944
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C182H272N54O45S7
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1
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IC50 > 5000 nM
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CP0474141
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,83S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-83-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C179H275N53O47S7
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1
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IC50 > 5000 nM
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CP0474143
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(3S)-3-amino-4-oxo-4-[[(1S,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51S,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-30-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
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C173H264N52O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0474144
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-60-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H270N52O44S7
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1
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IC50 > 5000 nM
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CP0474145
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69-bis(3-carbamimidamidopropyl)-92-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H266N50O47S7
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1
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IC50 > 5000 nM
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CP0475944
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-33,39-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C181H274N52O45S7
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1
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IC50 > 5000 nM
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CP0477813
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,89,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H274N56O45S6
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1
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IC50 > 5000 nM
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CP0477814
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C182H283N57O46S7
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1
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IC50 > 5000 nM
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CP0483525
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-4-(pyridin-2-ylmethyl)-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H268N54O45S7
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1
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IC50 > 5000 nM
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CP0483541
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H272N56O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0483542
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,89,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H274N54O45S6
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1
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| 1 |
IC50 > 5000 nM
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CP0483543
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(4S)-5-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-6-amino-2-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-77-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectane-30-carbonyl]amino]hexanoyl]amino]-5-oxopentanoic acid
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C172H269N53O46S7
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1
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IC50 > 5000 nM
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CP0486515
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-4-[(4-hydroxyphenyl)methyl]-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C179H269N53O46S7
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1
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IC50 > 5000 nM
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CP0498084
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-4,39-bis(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H267N55O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0501212
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,92,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69-bis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H271N51O45S7
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1
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IC50 > 5000 nM
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CP0508928
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-4,22,36,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H272N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0510073
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2-[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-77-[[(2S)-2,6-diaminohexanoyl]amino]-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-13-yl]acetic acid
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C178H278N54O43S7
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1
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IC50 > 5000 nM
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CP0510124
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H274N56O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0510125
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(3S)-3-amino-4-oxo-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-30-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamoyl]-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-4-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]butanoic acid
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C181H269N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0510592
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-13,33-bis(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C183H276N54O43S7
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1
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| 1 |
IC50 > 5000 nM
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CP0510594
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-36-[4-(dimethylamino)butyl]-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H275N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0511179
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-60-(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C177H272N52O46S7
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1
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IC50 > 5000 nM
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CP0534549
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-54-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C174H267N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0534550
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-48-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C178H273N53O46S7
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1
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| 1 |
IC50 > 5000 nM
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CP0536407
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,39,95-tetrakis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H276N52O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0544913
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(3S)-3-amino-4-[[(1S,4S,10S,13S,16S,19S,22S,25S,30R,33S,36S,39S,42S,45S,48S,51S,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,95-bis(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-36-methyl-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H264N52O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0556967
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-54-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H269N53O47S7
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1
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| 1 |
IC50 > 5000 nM
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CP0556977
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(3S)-3-amino-4-[[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33,57-bis(1H-indol-3-ylmethyl)-80-(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C181H270N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0858338
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(3S)-3-amino-4-[[(1S,4R,10S,13S,16R,19S,22S,25S,30R,33R,36S,39S,42R,45R,48S,51R,54R,57S,60R,63S,69S,72R,77S,80R,86S,89R,92S,95S)-30-[[(2R)-6-amino-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2R)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-80-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57-(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C175H267N53O47S7
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1
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| 1 |
IC50 > 5000 nM
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CP0858686
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(3S)-3-amino-4-[[(1S,4R,10R,13S,16R,19R,22R,25R,30S,33S,36R,39R,42S,45S,48R,51S,54S,57R,60S,63R,69R,72S,77R,80S,86S,89R,92S,95R)-30-[[(2R)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2S)-butan-2-yl]-39,45,69,92-tetrakis(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1S)-1-hydroxyethyl]-48-(hydroxymethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C176H276N54O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0859571
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2-[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-77-[(2S)-2-aminopropanamido]-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-19-(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-13-yl]acetic acid
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C175H271N53O43S7
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1
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| 1 |
IC50 > 5000 nM
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CP0866660
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(3S)-3-amino-4-[[(1S,4R,10S,13S,16R,19S,22R,25S,30R,33R,36S,39S,42R,45R,48S,51R,54R,57S,60S,63S,69S,72R,77S,80R,86S,89R,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2R)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1S)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-80-methyl-57-(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-4-oxobutanoic acid
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C173H265N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0882806
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}ethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C174H267N53O45S7
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1
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IC50 > 5000 nM
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CP0888688
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69-bis(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-92-methyl-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C173H264N50O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0888695
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-methyl-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C168H266N52O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0897693
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(3R)-4-[[(1S,4R,10S,13S,16R,19S,22R,25S,30R,33R,36S,39S,42R,45R,48S,51R,54R,57S,60R,63S,69S,72R,77R,80S,86S,89R,92S,95S)-30-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-22,36,95-tris(4-aminobutyl)-16,60-bis(2-amino-2-oxoethyl)-86-benzyl-4-[(2R)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-13,19-bis(carboxymethyl)-42-[(1S)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-(2-methylsulfanylethyl)-2,3a,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96-octacosaoxo-54-propan-2-yl-a,27,28,74,75,99-hexathia-2a,3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97-octacosazapentacyclo[49.46.4.225,72.06,10.063,67]trihectan-77-yl]amino]-3-[[(2R)-2-aminopropanoyl]amino]-4-oxobutanoic acid
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C179H276N54O46S7
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1
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| 1 |
IC50 > 5000 nM
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CP0897695
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-4-methyl-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C173H265N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0902070
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C170H267N53O44S7
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1
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| 1 |
IC50 > 5000 nM
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CP0910284
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36-bis(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-95-methyl-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C173H264N52O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0921370
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,95-bis(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-36-(2-carboxyethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C175H266N52O47S7
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1
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| 1 |
IC50 > 5000 nM
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CP0921604
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-89-methyl-57,80-bis(2-methylpropyl)-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C174H267N53O45S6
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1
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| 1 |
IC50 > 5000 nM
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CP0944602
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoylethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C179H276N54O46S7
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1
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IC50 > 5000 nM
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CP0958427
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(3S)-3-amino-3-{[(1R,4S,10S,13S,16S,19S,22S,25R,30R,33S,36S,39S,42S,45S,48S,51R,54S,57S,60S,63S,69S,72R,77R,80S,86S,89S,92S,95S)-30-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl]carbamoyl}-22,36,95-tris(4-aminobutyl)-86-benzyl-4-[(2S)-butan-2-yl]-45,69,92-tris(3-carbamimidamidopropyl)-16,60-bis(carbamoylmethyl)-13,19-bis(carboxymethyl)-42-[(1R)-1-hydroxyethyl]-48-(hydroxymethyl)-39-(1H-imidazol-5-ylmethyl)-33-(1H-indol-3-ylmethyl)-57,80-bis(2-methylpropyl)-89-[2-(methylsulfanyl)ethyl]-2,5,11,14,17,20,23,32,35,38,41,44,47,50,53,56,59,62,68,71,78,81,84,87,90,93,96,103-octacosaoxo-54-(propan-2-yl)-27,28,74,75,99,100-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,46,49,52,55,58,61,67,70,79,82,85,88,91,94,97,102-octacosaazapentacyclo[49.46.4.2^{25,72}.0^{6,10}.0^{63,67}]103n-77-yl]carbamoyl}propanoic acid
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C170H267N53O45S7
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1
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| 1 |
IC50 > 5000 nM
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CP0472022
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(4S)-6-fluoro-4-[(2R,4S)-2-pyridin-2-yl-4-(trifluoromethyl)piperidin-1-yl]-N-pyrimidin-4-yl-3,4-dihydro-2H-chromene-7-sulfonamide
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C24H23F4N5O3S
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1
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Kd > 1000 nM
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