Brief Information of the Compound and Protein
Compound Name
2-N-[4-[4-(trifluoromethoxy)phenoxy]phenyl]pyrazine-2,6-diamine
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PubChem ID
CID: 57328465
SID: 136330622
Canonical SMILES
Nc1cncc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1
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Compound Formula C17H13F3N4O2
Compound Structure
Protein Name
Sodium channel protein type 5 subunit alpha
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated sodium channel
Uniprot ID
Q14524
Gene Name
SCN5A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 1260 nM
   TI
   LI
   LO
   TS
2
IC50 = 1500 nM
   TI
   LI
   LO
   TS
3
IC50 = 10000 nM
   TI
   LI
   LO
   TS