| Compound ID |
Compound Name |
Compound Formula |
|
CP0344034
|
1-[4-(3-amino-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0037312
|
1-[4-(3-amino-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(4-fluoro-3-methylphenyl)urea
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0089286
|
1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenyl}-3-(3-trifluoromethylphenyl)urea
Show/Hide
|
C25H23N7O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0074807
|
1-[4-(3-amino-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0251111
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0479962
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0048071
|
1-(4-(4-amino-7-(pyrimidin-5-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C25H20N6OS
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0224320
|
1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenyl}-3-m-tolyl-urea
Show/Hide
|
C24H22N8O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0147307
|
4-amino-N-methyl-3-[4-[(3-methylphenyl)carbamoylamino]phenyl]thieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C23H21N5O2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0150869
|
1-[4-[4-amino-7-(1H-pyrrol-3-yl)thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C25H21N5OS
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0090480
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3,5-dimethylphenyl)urea
Show/Hide
|
C21H20N6O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0319203
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(4-fluoro-3-methylphenyl)urea
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0201862
|
1-[4-(3-amino-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H14F4N6O
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0090484
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3-chlorophenyl)urea
Show/Hide
|
C19H15ClN6O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0079746
|
1-[4-(3-amino-1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C21H20N6O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0172762
|
4-methyl-1-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methyl)piperazin-2-one
Show/Hide
|
C29H26N4O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0050939
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(2-methylphenyl)urea
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0037304
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H15F3N6O
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0044728
|
3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C20H17N5OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0295040
|
3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-chlorophenyl)urea
Show/Hide
|
C19H14ClN5OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0037302
|
1-[4-(3-amino-1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C21H19FN6O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0091712
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3,5-dimethylphenyl)urea
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0182014
|
1-[4-[4-amino-7-(1H-pyrazol-5-yl)thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C24H20N6OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0120604
|
ABT-348
Show/Hide
|
C25H21FN6O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0050938
|
1-[4-(3-amino-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(3-chlorophenyl)urea
Show/Hide
|
C19H15ClN6O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0316028
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H14F4N6O
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0090482
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3-methoxyphenyl)urea
Show/Hide
|
C20H18N6O2
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0037305
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-phenylurea
Show/Hide
|
C19H16N6O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0036099
|
1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea
Show/Hide
|
C21H18FN5O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0133165
|
1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C26H21N5OS
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0236089
|
1-(4-(4-amino-7-(pyridin-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C26H21N5OS
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0155688
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-methylphenyl)urea
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0222662
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-bromophenyl)urea
Show/Hide
|
C20H15BrN4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0340194
|
N-[3-[4-[6-[(4-methylpiperazin-1-yl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-yl]thiophen-2-yl]prop-2-ynyl]benzamide
Show/Hide
|
C30H29N5OS
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0316030
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3-chloro-4-fluorophenyl)urea
Show/Hide
|
C19H14ClFN6O
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0044727
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C21H19N5OS
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0199080
|
1-[4-(7-Amino-3-pyridin-3-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
Show/Hide
|
C25H21N7O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0122563
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H14F4N6O
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0264334
|
3-(5-(3-methoxyprop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C24H26N4OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0304895
|
1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenyl}-3-(3-chlorophenyl)urea
Show/Hide
|
C24H20ClN7O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0176330
|
1-[4-[4-amino-7-[3-(dimethylamino)prop-1-ynyl]thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C26H25N5OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0341780
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[(1-ethylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C17H20ClN7O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0079747
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3,5-difluorophenyl)urea
Show/Hide
|
C19H14F2N6O
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0037309
|
1-[4-(3-amino-1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-(3-chlorophenyl)urea
Show/Hide
|
C20H17ClN6O
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0091493
|
1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(4-fluoro-3-methylphenyl)urea
Show/Hide
|
C21H18FN5O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0147551
|
(1S,2S,3R,4R)-3-[[5-bromo-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C16H18BrN7O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0210299
|
N,N-dimethyl-2-[[3-[5-(3-phenoxyprop-1-ynyl)thiophen-3-yl]-1,4-dihydroindeno[1,2-c]pyrazol-6-yl]oxy]acetamide
Show/Hide
|
C27H23N3O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0291429
|
3-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methyl)thiazolidine
Show/Hide
|
C27H23N3OS2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0386042
|
6-(4-methylpiperazin-1-yl)-3-(5-(3-phenoxyprop-1-ynyl)-thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C28H26N4OS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0152033
|
3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluorophenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C20H16FN5OS
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0037248
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-methoxyphenyl)urea
Show/Hide
|
C21H18N4O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0081848
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3,5-dimethylphenyl)urea
Show/Hide
|
C22H21N5OS
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0051872
|
1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-p-tolylurea
Show/Hide
|
C21H19N5O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0051888
|
1-(4-(3-amino-7-(2-(dimethylamino)ethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C25H28N6O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0157315
|
3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-methoxyphenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C21H19N5O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0153309
|
1-[4-(3-amino-1-methylpyrazolo[3,4-c]pyridin-4-yl)phenyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H16F4N6O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0059138
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C21H17FN4O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0210353
|
1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C21H19N5O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0172755
|
6-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-methoxyethoxy)-prop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C23H21N5O2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0083841
|
1-[4-[4-amino-7-(1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C24H20N6OS
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0113930
|
1-[4-[4-amino-7-(furan-3-yl)thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C25H20N4O2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0154076
|
1-[4-[4-amino-7-(1-methylpyrazol-4-yl)thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C25H22N6OS
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0152032
|
3-{4-[4-amino-6-(3-hydroxypropyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
|
C23H23N5O2S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0037247
|
3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-(3-bromophenyl)urea
Show/Hide
|
C21H17BrN4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0096108
|
1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C24H25N5O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0419608
|
1-(4-(3-amino-1-(2-(diethylamino)ethoxy)-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C27H31FN6O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0339687
|
1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(naphthalen-2-yl)urea
Show/Hide
|
C24H18N4OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0296437
|
1-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno-[1,2-c]pyrazol-3-yl)thiophen-2-yl)prop-2-ynyl)-3-phenylurea
Show/Hide
|
C30H30N6OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0268946
|
6-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)-thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C26H19N5OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0037313
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-(4-methylphenyl)urea
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0221111
|
1-(4-(3-amino-1-(2-methoxyethoxy)-1H-indazol-4-yl)phenyl)-3-(3-chlorophenyl)urea
Show/Hide
|
C23H22ClN5O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0021160
|
7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-methoxyethoxy)-prop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C23H21N5O2S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0096073
|
3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)thieno[2,3-d]pyrimidin-6-yl]propanamide
Show/Hide
|
C23H22N6O2S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0155684
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-nitrophenyl)urea
Show/Hide
|
C20H15N5O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0091128
|
1-[4-(7-Amino-3-phenyl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
Show/Hide
|
C26H22N6O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C22H27FN4O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0059152
|
3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-(3-chlorophenyl)urea
Show/Hide
|
C21H17ClN4O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0162815
|
1-methyl-4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methyl)piperazin-2-one
Show/Hide
|
C29H26N4O2S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0057693
|
3-{4-[4-amino-6-(2-hydroxyethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
|
C22H21N5O2S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0152035
|
3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluorophenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C20H16FN5OS
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0091721
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-chloro-4-fluorophenyl)urea
Show/Hide
|
C20H14ClFN4O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0115015
|
Aminopyrimidine (Scaffold VI)
Show/Hide
|
C24H30FN7O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0059149
|
3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C22H19FN4O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0210302
|
4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methyl)piperazine-1-carbaldehyde
Show/Hide
|
C29H27N5O2S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0139730
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C16H18ClN7O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0091717
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-fluorophenyl)urea
Show/Hide
|
C20H15FN4O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0140105
|
1-[4-(7-Amino-3-benzo[1,3]dioxol-5-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
Show/Hide
|
C27H22N6O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0103098
|
3-(4-{3-amino-7-[2-(morpholin-4-yl)ethoxy]-1,2-benzoxazol-4-yl}phenyl)-1-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C27H28FN5O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0091126
|
1-[4-(7-Amino-3-thiophen-3-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
Show/Hide
|
C24H20N6OS
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0163494
|
(E)-3-[4-amino-3-[4-[(3-methylphenyl)carbamoylamino]phenyl]thieno[3,2-c]pyridin-7-yl]-N-methylprop-2-enamide
Show/Hide
|
C25H23N5O2S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0091716
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-fluorophenyl)urea
Show/Hide
|
C20H15FN4O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0179704
|
1-[4-(3-amino-1-methylindazol-4-yl)phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C22H21N5O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0155689
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-phenylurea
Show/Hide
|
C20H16N4O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0346372
|
3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C26H30N4O2S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0063147
|
3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C22H21N5OS
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0254103
|
3-(4-{4-amino-6-propylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
|
C23H23N5OS
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0059142
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-chlorophenyl)urea
Show/Hide
|
C20H15ClN4O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0096496
|
1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-chlorophenyl)urea
Show/Hide
|
C20H16ClN5O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0203558
|
N-[3-[4-[6-[(4-methylpiperazin-1-yl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-yl]thiophen-2-yl]prop-2-ynyl]aniline
Show/Hide
|
C29H29N5S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0043245
|
1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]-pyrimidin-6-yl]phenyl}-3-(2-fluoro-5-trifluoromethylphenyl)-urea
Show/Hide
|
C25H19F4N7O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0168629
|
1-(4-(4-amino-7-(4-hydroxyphenyl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C27H22N4O2S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0442510
|
(4-methylpiperazin-1-yl)(3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methanone
Show/Hide
|
C29H26N4O2S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0199082
|
1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenyl}-3-(3-fluorophenyl)urea
Show/Hide
|
C24H20FN7O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0036978
|
3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H17F3N4O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0113932
|
1-[4-(4-amino-7-thiophen-3-ylthieno[3,2-c]pyridin-3-yl)phenyl]-3-(3-methylphenyl)urea
Show/Hide
|
C25H20N4OS2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0269871
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-chloro-4-methylphenyl)urea
Show/Hide
|
C21H17ClN4O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0051219
|
1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
Show/Hide
|
C21H16F3N5O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0121476
|
1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C21H18N4OS
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0162642
|
1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-ethylphenyl)urea
Show/Hide
|
C22H20N4OS
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0221112
|
1-(4-(3-amino-1-(2-methoxyethoxy)-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C24H24FN5O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0316461
|
1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
|
C27H22N4OS
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0279595
|
1-[4-(7-Amino-3-cyclopropyl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
Show/Hide
|
C23H22N6O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0081852
|
3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
|
C26H22N6OS
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0136506
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methoxyphenyl)urea
Show/Hide
|
C21H19N5O2S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0287750
|
1-[4-(4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C21H18FN5OS
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0122562
|
1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-(4-fluoro-3-methylphenyl)urea
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0352573
|
3-(5-(3-(3,4-dimethylphenoxy)prop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C31H32N4OS
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0045811
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-chlorophenyl)urea
Show/Hide
|
C20H16ClN5OS
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0043241
|
1-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
Show/Hide
|
C20H15F3N6O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0124051
|
(1S,2S,3R,4R)-3-[[2-[(1-methylpyrazol-4-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C17H18F3N7O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0034675
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-phenylurea
Show/Hide
|
C20H17N5OS
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0155685
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-chloro-4-methoxyphenyl)urea
Show/Hide
|
C21H17ClN4O3
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0307437
|
1-[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]-3-thiophen-3-ylurea
Show/Hide
|
C17H14N6OS
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0059139
|
3-[4-(3-amino-7-methyl-1,2-benzoxazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea
Show/Hide
|
C22H19FN4O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0211569
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3-fluoro-4-methylphenyl)urea
Show/Hide
|
C21H17FN4O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0021159
|
6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C29H28N4OS
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0291421
|
4-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno-[1,2-c]pyrazol-3-yl)thiophen-2-yl)but-3-yn-1-ol
Show/Hide
|
C24H26N4OS
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0133159
|
1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3,4-dimethylphenyl)urea
Show/Hide
|
C22H20N4OS
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0349470
|
(1S,2S,3R,4R)-3-[[2-[(1-benzylpyrazol-4-yl)amino]-5-chloropyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C22H22ClN7O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0059141
|
3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-methylphenyl)urea
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0346491
|
6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-(pyridin-3-yloxy)-prop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C28H27N5OS
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0127275
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[[1-[(3R)-piperidin-3-yl]pyrazol-4-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C20H25ClN8O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0081849
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H15F4N5OS
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0152002
|
-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -(3-bromophenyl)urea
Show/Hide
|
C20H16BrN5OS
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0202726
|
1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-(3-chlorophenyl)urea
Show/Hide
|
C19H15ClN6O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0045807
|
1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-4-methylphenyl)urea
Show/Hide
|
C21H18FN5O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0062418
|
1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(thiophen-2-yl)urea
Show/Hide
|
C18H14N4OS2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0307111
|
1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3,5-dimethylphenyl)urea
Show/Hide
|
C22H20N4OS
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0160815
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C17H20ClN7O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0162309
|
6-((1H-pyrazol-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C27H20N4OS
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0497835
|
1-[4-(7-Amino-3-thiophen-2-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
Show/Hide
|
C24H20N6OS
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0125381
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[[1-[[(2R)-pyrrolidin-2-yl]methyl]pyrazol-4-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C20H25ClN8O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0295966
|
3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H18F3N5OS
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0172766
|
phenyl N-[3-[4-[6-[(4-methylpiperazin-1-yl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-yl]thiophen-2-yl]prop-2-ynyl]carbamate
Show/Hide
|
C30H29N5O2S
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0036034
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C21H16F3N5OS
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0081841
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-fluorophenyl)urea
Show/Hide
|
C20H16FN5OS
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0081787
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-methylphenyl)urea
Show/Hide
|
C21H19N5OS
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0081854
|
3-{4-[4-amino-6-(pyridin-4-ylmethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
|
C26H22N6OS
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0160472
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-fluorophenyl)urea
Show/Hide
|
C20H16FN5OS
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0141536
|
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-3-methyl-1-(3-methylphenyl)urea
Show/Hide
|
C22H21N5OS
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0270482
|
1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenyl}-3-(4-fluoro-3-trifluoromethylphenyl)urea
Show/Hide
|
C25H19F4N7O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0114909
|
(1S,2S,3R,4R)-3-[[5-chloro-2-[(1-piperidin-4-ylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
|
C20H25ClN8O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0074037
|
1-(4-(3-amino-7-(2-morpholinoethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea
Show/Hide
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C27H30N6O3
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1
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| 1 |
IC50 = 56 nM
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CP0160366
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-chlorophenyl)urea
Show/Hide
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C20H15ClN4OS
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1
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| 1 |
IC50 = 56 nM
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CP0339686
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1-(4-(4-amino-7-(3-(methylcarbamoyl)phenyl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea
Show/Hide
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C29H25N5O2S
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1
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| 1 |
IC50 = 56 nM
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CP0340207
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6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C30H30N4OS
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1
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| 1 |
IC50 = 58 nM
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CP0297570
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1-[4-(4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl)phenyl]-3-[4-(trifluoromethyl)phenyl]urea
Show/Hide
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C21H16F3N5OS
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1
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| 1 |
IC50 = 61 nM
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CP0344032
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1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Show/Hide
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C20H17FN6O
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1
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| 1 |
IC50 = 61 nM
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CP0168630
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(thiophen-3-yl)urea
Show/Hide
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C18H14N4OS2
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1
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| 1 |
IC50 = 61 nM
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CP0124052
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(1R,2S,3R,4S)-3-[[2-[(1-methylpyrazol-4-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]bicyclo[2.2.1]heptane-2-carboxamide
Show/Hide
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C17H20F3N7O
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1
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| 1 |
IC50 = 61 nM
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CP0172756
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3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl)-7-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C26H30N4O2S
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1
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| 1 |
IC50 = 62 nM
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CP0089874
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3-{4-[4-amino-6-(2-methoxyethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
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C23H23N5O2S
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1
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| 1 |
IC50 = 64 nM
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CP0215870
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1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea
Show/Hide
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C30H34N6OS
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1
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| 1 |
IC50 = 64 nM
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CP0079745
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1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-(3,5-dimethylphenyl)urea
Show/Hide
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C21H20N6O
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1
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| 1 |
IC50 = 65 nM
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CP0059137
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-[3-(trifluoromethyl)phenyl]urea
Show/Hide
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C21H15F3N4O2
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1
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| 1 |
IC50 = 65 nM
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CP0208104
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-methoxyphenyl)urea
Show/Hide
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C21H19N5O2S
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1
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| 1 |
IC50 = 69 nM
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CP0254788
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1-[4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]-3-m-tolylurea
Show/Hide
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C20H18N6O
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1
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| 1 |
IC50 = 70 nM
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CP0375437
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1-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Show/Hide
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C20H14F4N6O
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1
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| 1 |
IC50 = 70 nM
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CP0305789
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6-((1-methylpiperidin-4-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3 -yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C30H29N3OS
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1
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| 1 |
IC50 = 71 nM
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CP0133164
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-phenylurea
Show/Hide
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C20H16N4OS
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1
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| 1 |
IC50 = 72 nM
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CP0114908
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(1S,2S,3R,4R)-3-[[5-chloro-2-[[1-(2-morpholin-4-ylethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
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C21H27ClN8O2
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1
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| 1 |
IC50 = 78 nM
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CP0059140
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Show/Hide
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C21H14F4N4O2
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1
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| 1 |
IC50 = 80 nM
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CP0104536
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1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylurea
Show/Hide
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C21H19N5O
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1
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| 1 |
IC50 = 80 nM
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CP0288709
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(3,5-difluorophenyl)urea
Show/Hide
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C20H14F2N4O2
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1
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| 1 |
IC50 = 81 nM
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CP0093659
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3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-chlorophenyl)-1-(3-methylphenyl)urea
Show/Hide
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C20H16ClN5OS
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1
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| 1 |
IC50 = 83 nM
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CP0152876
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(1R,2S,3R,4S)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]heptane-2-carboxamide
Show/Hide
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C16H20ClN7O
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1
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| 1 |
IC50 = 84 nM
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CP0270478
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1-(4-(7-Amino-3-bromopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-m-tolylurea
Show/Hide
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C20H17BrN6O
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1
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| 1 |
IC50 = 86 nM
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CP0341781
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(1S,2S,3R,4R)-3-[[5-chloro-2-[[1-[2-(methylamino)-2-oxoethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
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C18H21ClN8O2
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1
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| 1 |
IC50 = 89 nM
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CP0210300
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6-(2-methoxyethoxy)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C26H22N2O3S
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1
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| 1 |
IC50 = 92 nM
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CP0091711
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-[4-fluoro-3-(trifluoromethyl)phenyl]urea
Show/Hide
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C21H14F4N4O2
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1
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| 1 |
IC50 = 94 nM
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CP0074035
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-chlorophenyl)urea
Show/Hide
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C20H16ClN5OS
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1
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| 1 |
IC50 = 96 nM
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CP0037307
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1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
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C20H15F3N6O
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1
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| 1 |
IC50 = 99 nM
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CP0296360
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6-((4-methylpiperazin-1-yl)methyl)-3-(4-(3-phenoxyprop-1-ynyl)thiophen-2 -yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C29H28N4OS
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1
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| 1 |
IC50 = 99 nM
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CP0057695
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3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methoxyphenyl)-1-(3-methylphenyl)urea
Show/Hide
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C21H19N5O2S
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1
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| 1 |
IC50 = 100 nM
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CP0160595
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3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-chlorophenyl)-1-(3-methylphenyl)urea
Show/Hide
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C20H16ClN5OS
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1
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| 1 |
IC50 = 100 nM
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CP0155687
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-methoxyphenyl)urea
Show/Hide
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C21H18N4O3
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1
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| 1 |
IC50 = 106 nM
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CP0210306
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N-[3-[4-[6-[(4-methylpiperazin-1-yl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-yl]thiophen-2-yl]prop-2-ynyl]benzenesulfonamide
Show/Hide
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C29H29N5O2S2
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1
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| 1 |
IC50 = 109 nM
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CP0063670
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(2-methoxyphenyl)urea
Show/Hide
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C21H19N5O2S
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1
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| 1 |
IC50 = 110 nM
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CP0141555
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(2-fluorophenyl)urea
Show/Hide
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C20H16FN5OS
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1
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| 1 |
IC50 = 110 nM
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CP0296435
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6-((4-methylpiperidin-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C30H29N3OS
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1
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| 1 |
IC50 = 112 nM
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CP0179895
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1-((5-(7-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea
Show/Hide
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C29H32N6OS
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1
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| 1 |
IC50 = 115 nM
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CP0063671
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-bromophenyl)urea
Show/Hide
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C20H16BrN5OS
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1
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| 1 |
IC50 = 120 nM
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CP0155686
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-[4-(trifluoromethoxy)phenyl]urea
Show/Hide
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C21H15F3N4O3
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1
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| 1 |
IC50 = 123 nM
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CP0152031
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3-{4-[4-amino-6-(propan-2-yl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
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C23H23N5OS
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1
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| 1 |
IC50 = 130 nM
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CP0339688
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p-tolylurea
Show/Hide
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C21H18N4OS
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1
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| 1 |
IC50 = 141 nM
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CP0167328
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1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea
Show/Hide
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C30H34N6OS
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1
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| 1 |
IC50 = 146 nM
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CP0215864
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1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea
Show/Hide
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C29H32N6OS
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1
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| 1 |
IC50 = 146 nM
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CP0475124
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea
Show/Hide
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C20H15FN4OS
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1
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| 1 |
IC50 = 147 nM
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CP0305788
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6-((1H-1,2,3-triazol-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)-thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C26H19N5OS
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1
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| 1 |
IC50 = 148 nM
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CP0806700
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1-(11-Amino-5,6,6a,11b-tetrahydro-7-thia-8,10-diaza-benzo[c]fluoren-3-yl)-3-m-tolyl-urea
Show/Hide
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C22H21N5OS
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1
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| 1 |
IC50 = 150 nM
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CP0210359
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1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Show/Hide
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C21H15F4N5O
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1
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| 1 |
IC50 = 151 nM
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CP0061594
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3,5-dichlorophenyl)urea
Show/Hide
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C20H15Cl2N5OS
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1
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| 1 |
IC50 = 160 nM
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CP0152879
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(1S,2S,3R,4R)-3-[[2-[[1-(2-amino-2-oxoethyl)pyrazol-4-yl]amino]-5-chloropyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
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C17H19ClN8O2
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1
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| 1 |
IC50 = 167 nM
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CP0325803
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5-[4-(1,3-Benzoxazol-2-ylamino)phenyl]-6-methylthieno-[2,3-d]pyrimidin-4-amine
Show/Hide
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C20H15N5OS
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1
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| 1 |
IC50 = 170 nM
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CP0325810
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3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-cyclohexylurea
Show/Hide
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C21H25N5OS
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1
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| 1 |
IC50 = 170 nM
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CP0255323
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1-cyclopropyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea
Show/Hide
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C32H36N6OS
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1
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| 1 |
IC50 = 171 nM
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CP0037245
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-[4-(trifluoromethyl)phenyl]urea
Show/Hide
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C21H15F3N4O2
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1
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| 1 |
IC50 = 173 nM
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CP0162801
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3-(5-(3-(3-chlorophenoxy)prop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C29H27ClN4OS
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1
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| 1 |
IC50 = 178 nM
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CP0104550
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3-(5-(3-(2-chlorophenoxy)prop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C29H27ClN4OS
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1
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| 1 |
IC50 = 178 nM
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CP0059136
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3-{4-[3-amino-7-(trifluoromethoxy)-1,2-benzoxazol-4-yl]phenyl}-1-(2-fluoro-5-methylphenyl)urea
Show/Hide
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C22H16F4N4O3
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1
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| 1 |
IC50 = 179 nM
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CP0254105
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3-(4-{4-amino-6-[(dimethylamino)methyl]thieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
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C23H24N6OS
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1
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| 1 |
IC50 = 180 nM
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CP0288566
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1-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-3-butylurea
Show/Hide
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C17H19N5OS
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1
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| 1 |
IC50 = 180 nM
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CP0039476
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1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-(3-(trifluoromethyl)phenyl)urea
Show/Hide
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C30H31F3N6OS
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1
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| 1 |
IC50 = 195 nM
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CP0276193
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7-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C29H28N4OS
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1
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| 1 |
IC50 = 197 nM
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CP0284909
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-cyanophenyl)urea
Show/Hide
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C21H15N5OS
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1
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| 1 |
IC50 = 198 nM
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CP0215867
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1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-1-propyl-3-m-tolylurea
Show/Hide
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C32H38N6OS
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1
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| 1 |
IC50 = 198 nM
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CP0034665
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3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)thieno[2,3-d]pyrimidin-6-yl]-N,N-dimethylpropanamide
Show/Hide
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C25H26N6O2S
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1
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| 1 |
IC50 = 210 nM
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CP0141531
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3-{4-[4-amino-6-(morpholin-4-ylmethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea
Show/Hide
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C25H26N6O2S
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1
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| 1 |
IC50 = 210 nM
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CP0179927
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1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)urea
Show/Hide
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C30H31F3N6O2S
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1
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| 1 |
IC50 = 218 nM
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CP0224319
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7-Amino-6-[4-(3-m-tolylureido)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid Ethyl Ester
Show/Hide
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C23H22N6O3
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1
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| 1 |
IC50 = 220 nM
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CP0081855
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3-(4-{4-amino-6-[2-(dimethylamino)ethyl]thieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
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C24H26N6OS
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1
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| 1 |
IC50 = 230 nM
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CP0186693
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3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)urea
Show/Hide
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C30H30F4N6OS
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1
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| 1 |
IC50 = 233 nM
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CP0043240
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1-[4-(7-Amino-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)phenyl]-3-m-tolylurea
Show/Hide
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C21H20N6O
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1
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| 1 |
IC50 = 250 nM
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CP0089852
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(2-methylphenyl)urea
Show/Hide
|
C21H19N5OS
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1
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| 1 |
IC50 = 260 nM
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CP0081851
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3-(4-{4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
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C27H23N5OS
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1
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| 1 |
IC50 = 280 nM
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CP0073847
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3-{3-[4-(4-Amino-6-methyl-thieno[2,3-d]pyrimidin-5-yl)-phenyl]-ureido}-benzoic acid ethyl ester
Show/Hide
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C23H21N5O3S
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1
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| 1 |
IC50 = 290 nM
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CP0296427
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6-((4-methylpiperazin-1-yl)methyl)-3-(5-(4-phenoxybut-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C30H30N4OS
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1
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| 1 |
IC50 = 313 nM
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CP0352622
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6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-2 -yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C29H28N4OS
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1
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| 1 |
IC50 = 316 nM
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CP0057689
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3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)thieno[2,3-d]pyrimidin-6-yl]-N-methylpropanamide
Show/Hide
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C24H24N6O2S
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1
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| 1 |
IC50 = 330 nM
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CP0297574
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-benzylurea
Show/Hide
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C21H19N5OS
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1
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| 1 |
IC50 = 330 nM
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CP0152001
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(2-chlorophenyl)urea
Show/Hide
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C20H16ClN5OS
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1
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| 1 |
IC50 = 340 nM
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CP0162295
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3-(5-(3-(4-chlorophenoxy)prop-1-ynyl)thiophen-3-yl)-6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C29H27ClN4OS
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1
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| 1 |
IC50 = 419 nM
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CP0036948
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(2-fluorophenyl)urea
Show/Hide
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C20H15FN4O2
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1
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| 1 |
IC50 = 497 nM
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CP0172746
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6-((4-methylpiperazin-1-yl)methyl)-3-(5-(pent-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C25H28N4S
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1
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| 1 |
IC50 = 503 nM
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CP0344465
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6-((4-methylpiperazin-1-yl)methyl)-3-(5-(4-phenylbut-1-ynyl)-thiophen-3-yl) -1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
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C30H30N4S
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1
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| 1 |
IC50 = 542 nM
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CP0096109
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3-(4-{4-amino-6-[(4-methylpiperazin-1-yl)methyl]thieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea
Show/Hide
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C26H29N7OS
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1
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| 1 |
IC50 = 590 nM
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CP0141554
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N-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-2-(3-methylphenyl)acetamide
Show/Hide
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C22H20N4OS
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1
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| 1 |
IC50 = 760 nM
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CP0192406
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(cyclohexylmethyl)urea
Show/Hide
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C21H25N5OS
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1
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| 1 |
IC50 = 790 nM
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CP0062440
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1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(naphthalen-1-yl)urea
Show/Hide
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C24H18N4OS
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1
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| 1 |
IC50 = 895 nM
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CP0036947
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3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-[2-(trifluoromethoxy)phenyl]urea
Show/Hide
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C21H15F3N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0325802
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1-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-2-cyano-3-methylbenzene-1-guanidine
Show/Hide
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C22H19N7S
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1
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| 1 |
IC50 = 1100 nM
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CP0142463
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1-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-3-(2-methylpropyl)urea
Show/Hide
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C17H19N5OS
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1
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| 1 |
IC50 = 1700 nM
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CP0331981
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-methyl-1-(3-methylphenyl)urea
Show/Hide
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C22H21N5OS
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1
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| 1 |
IC50 = 1900 nM
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CP0276794
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(5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl m-tolylcarbamate
Show/Hide
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C29H31N5O2S
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1
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| 1 |
IC50 = 2000 nM
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CP0305787
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4-(4-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)prop-2-ynyloxy)benzyl)-morpholine
Show/Hide
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C34H37N5O2S
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1
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| 1 |
IC50 = 2140 nM
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CP0309905
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3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)thiourea
Show/Hide
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C21H19N5S2
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1
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| 1 |
IC50 = 2800 nM
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CP0217164
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5-(4-Aminophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine
Show/Hide
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C13H12N4S
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1
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| 1 |
IC50 = 4600 nM
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CP0287748
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N-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-3-methylbenzamide
Show/Hide
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C21H18N4OS
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1
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| 1 |
IC50 = 4600 nM
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CP0498107
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4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-N-phenylbenzamide
Show/Hide
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C21H18N4OS
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1
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| 1 |
IC50 > 50000 nM
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CP0498108
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N-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1H-indole-2-carboxamide
Show/Hide
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C22H17N5OS
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1
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| 1 |
IC50 > 50000 nM
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CP0512344
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N-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)benzenesulfonamide
Show/Hide
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C19H16N4O2S2
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1
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| 1 |
IC50 > 50000 nM
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CP0047886
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2-[4-[[4-[[(1R,2R,3S,4S)-3-carbamoyl-2-bicyclo[2.2.1]hept-5-enyl]amino]-5-chloropyrimidin-2-yl]amino]pyrazol-1-yl]acetic acid
Show/Hide
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C17H18ClN7O3
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1
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| 1 |
IC50 > 316 nM
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CP0124050
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(1S,2S,3R,4R)-3-[[2-[(1-methylpyrazol-4-yl)amino]-5-nitropyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
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C16H18N8O3
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1
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| 1 |
IC50 > 316 nM
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CP0125378
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(1R,2R,3S,4S)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]heptane-2-carboxamide
Show/Hide
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C16H20ClN7O
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1
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| 1 |
IC50 > 316 nM
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CP0152875
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(1S,2S,3R,4R)-N-methyl-3-[[2-[(1-methylpyrazol-4-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Show/Hide
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C18H20F3N7O
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1
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| 1 |
IC50 > 316 nM
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