Brief Information of the Compound and Protein
Compound Name
3-{4-[3-amino-7-(trifluoromethoxy)-1,2-benzoxazol-4-yl]phenyl}-1-(2-fluoro-5-methylphenyl)urea
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PubChem ID
CID: 11856735
SID: 17169466
Canonical SMILES
Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2ccc(OC(F)(F)F)c3onc(N)c23)c1
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Compound Formula C22H16F4N4O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 179 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 158 nM