Brief Information of the Compound and Protein
Compound Name
3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-3-methyl-1-(3-methylphenyl)urea
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PubChem ID
CID: 6539979
SID: 16648052
Canonical SMILES
CN(C(=O)Nc1cccc(C)c1)c1ccc(cc1)-c1c(C)sc2ncnc(N)c12
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Compound Formula C22H21N5OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 54.95 nM
2 IC50 = 55 nM