Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Aminopyrimidine (Scaffold VI)
    Show/Hide
 PubChem ID
CID: 11569967
SID: 16766075
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2ncc(F)c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(N)=O)n2)cc1C
    Show/Hide
Compound Formula C24H30FN7O
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 95 nM