Brief Information of the Compound and Protein
Compound Name
1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-(4-fluoro-3-methylphenyl)urea
    Show/Hide
PubChem ID
CID: 11653702
SID: 16757217
Canonical SMILES
Cc1cc(NC(=O)Nc2ccc(cc2)-c2nccc3n[nH]c(N)c23)ccc1F
    Show/Hide
Compound Formula C20H17FN6O
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM