Brief Information of the Compound and Protein
Compound Name
(E)-3-[4-amino-3-[4-[(3-methylphenyl)carbamoylamino]phenyl]thieno[3,2-c]pyridin-7-yl]-N-methylprop-2-enamide
    Show/Hide
PubChem ID
CID: 18450585
SID: 92389800
Canonical SMILES
CNC(=O)\C=C\c1cnc(N)c2c(csc12)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1
    Show/Hide
Compound Formula C25H23N5O2S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM