Brief Information of the Compound and Protein
Compound Name
3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)thieno[2,3-d]pyrimidin-6-yl]-N-methylpropanamide
    Show/Hide
PubChem ID
CID: 6540007
SID: 16722457
Canonical SMILES
CNC(=O)CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1
    Show/Hide
Compound Formula C24H24N6O2S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 331.13 nM