Brief Information of the Compound and Protein
Compound Name
3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methoxyphenyl)-1-(3-methylphenyl)urea
    Show/Hide
PubChem ID
CID: 6540023
SID: 16816031
Canonical SMILES
COc1cc(NC(=O)Nc2cccc(C)c2)ccc1-c1csc2ncnc(N)c12
    Show/Hide
Compound Formula C21H19N5O2S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100 nM