Brief Information of the Compound and Protein
Compound Name
1-(4-(3-amino-1-(2-methoxyethoxy)-1H-indazol-4-yl)phenyl)-3-(3-chlorophenyl)urea
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PubChem ID
CID: 44420777
Canonical SMILES
COCCOn1nc(N)c2c(cccc12)-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1
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Compound Formula C23H22ClN5O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM