Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno-[1,2-c]pyrazol-3-yl)thiophen-2-yl)but-3-yn-1-ol
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 PubChem ID
CID: 16220281
SID: 24902692
Canonical SMILES
CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCCO)c2)CC1
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Compound Formula C24H26N4OS
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM