Brief Information of the Compound and Protein
Compound Name
1-[4-(3-amino-1H-pyrazolo[4,3-c]pyridin-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
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PubChem ID
CID: 11653701
SID: 16757216
Canonical SMILES
Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nccc3n[nH]c(N)c23)c1
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Compound Formula C20H17FN6O
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 61 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM