Brief Information of the Compound and Protein
Compound Name
1-[4-(7-Amino-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)phenyl]-3-m-tolylurea
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PubChem ID
CID: 24894506
SID: 53778714
Canonical SMILES
Cc1cccc(NC(=O)Nc2ccc(cc2)-c2c(C)nc3ccnn3c2N)c1
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Compound Formula C21H20N6O
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 39 nM