Brief Information of the Compound and Protein
Compound Name
1-[4-(7-Amino-3-thiophen-2-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea
    Show/Hide
PubChem ID
CID: 24894618
SID: 53778828
Canonical SMILES
Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cnc3c(cnn3c2N)-c2cccs2)c1
    Show/Hide
Compound Formula C24H20N6OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 49 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM