Brief Information of the Compound and Protein
Compound Name
7-Amino-6-[4-(3-m-tolylureido)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid Ethyl Ester
    Show/Hide
PubChem ID
CID: 24894621
SID: 53778831
Canonical SMILES
CCOC(=O)c1cnn2c(N)c(cnc12)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1
    Show/Hide
Compound Formula C23H22N6O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25 nM