Brief Information of the Compound and Protein
Compound Name
1-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
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PubChem ID
CID: 24765042
SID: 49685047
Canonical SMILES
Nc1c(cnc2ccnn12)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1
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Compound Formula C20H15F3N6O
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM